Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Tatsuya Shiraishi, MD (Cardiology)
Dr. Shiraishi graduated from the Kyoto University School of Medicine. He worked as a cardiologist at Edogawa Hospital, and after joining Ubie, he became the Director of East Nihonbashi Internal Medicine Clinic.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Rashes
Have a fever
Intensely red eye
Redness of the skin
Fingers are red and swollen
Lymph swollen
Pain in the mouth
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Kawasaki disease causes swelling, called inflammation, in the walls of small to medium-sized blood vessels that carry blood throughout the body. Kawasaki disease most often affects the heart arteries in children. Those arteries supply oxygen-rich blood to the heart. It also causes swelling in glands, called lymph nodes, and mucous membranes inside the mouth, nose, eyes and throat. Symptoms include a fever greater than 102.2 degrees Fahrenheit (39 degrees Celsius) for five or more days, a rash on the main part of the body or in the genital area, an enlarged lymph node in the neck, very red eyes without a thick discharge, red, dry, cracked lips and a red, swollen tongue, swollen, red skin on the palms of the hands and the soles of the feet. Later the skin on fingers and toes peels.
Your doctor may ask these questions to check for this disease:
The standard treatment is with anti-inflammatory drugs. The doctor may recommend IVIG, a mixture of antibodies that will reduce heart inflammation. If there is damage to the heart's blood vessels, lifelong follow-up with a heart specialist may be needed.
Rife E, Gedalia A. Kawasaki Disease: an Update. Curr Rheumatol Rep. 2020 Sep 13;22(10):75. doi: 10.1007/s11926-020-00941-4. PMID: 32924089; PMCID: PMC7487199.
https://link.springer.com/article/10.1007/s11926-020-00941-4Agarwal S, Agrawal DK. Kawasaki disease: etiopathogenesis and novel treatment strategies. Expert Rev Clin Immunol. 2017 Mar;13(3):247-258. doi: 10.1080/1744666X.2017.1232165. Epub 2016 Sep 13. PMID: 27590181; PMCID: PMC5542821.
https://www.tandfonline.com/doi/full/10.1080/1744666X.2017.1232165Singh S, Jindal AK, Pilania RK. Diagnosis of Kawasaki disease. Int J Rheum Dis. 2018 Jan;21(1):36-44. doi: 10.1111/1756-185X.13224. Epub 2017 Nov 13. PMID: 29131549; PMCID: PMC7159575.
https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.13224Sundel RP. Kawasaki disease. Rheum Dis Clin North Am. 2015;41(1):63-73, viii. doi: 10.1016/j.rdc.2014.09.010. PMID: 25399940.
https://rheumatic.theclinics.com//retrieve/pii/S0889857X14000994Kawasaki Disease - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/kawasaki-disease/symptoms-causes/syc-20354598#:~:text=Kawasaki%20disease%20causes%20swelling%2C%20called,rich%20blood%20to%20the%20heartMale, 30s
I got more answers in one minute through your site than I did in three hours with Google.
(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
(Sep 27, 2024)
Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
(Sep 26, 2024)
Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Tatsuya Shiraishi, MD (Cardiology)
Dr. Shiraishi graduated from the Kyoto University School of Medicine. He worked as a cardiologist at Edogawa Hospital, and after joining Ubie, he became the Director of East Nihonbashi Internal Medicine Clinic.
Our symptom checker AI is continuously refined with input from experienced physicians, empowering them to make more accurate diagnoses.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1