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Lymph swollen
Swelling of the affected area
Swollen lymph nodes
The problem area has swollen
Affected area is swollen
Swollen lymph nodes in the neck
Affected area has swelled up
Not seeing your symptoms? No worries!
What is Kimura's Disease?
Kimura disease is a rare, non-cancerous chronic inflammatory disease characterized by lymph node enlargement in the head and neck, often accompanied by eosinophilia (high level of disease-fighting white blood cells called eosinophils in the blood) and increased serum IgE (a type of antibody). The cause is unknown but could be due to allergic reactions, trauma, or immune system problems. It's more common in young Asian men.
Typical Symptoms of Kimura's Disease
- Swollen lymph nodes or lumps in the neck, armpits, groin, or behind the ears
- Hard or stiff skin
- Skin lumps
- Soft lump/s on skin
- Neck lump
- Swelling in the affected area
- Dark spots on skin
- Itchy skin
Diagnostic Questions for Kimura's Disease
Your doctor may ask these questions to check for this disease:
- Do you have any swollen lymph nodes or lumps in your neck, armpits, groin, or behind your ears?
- Have you noticed any hard or stiff areas on your skin?
- Have you noticed any lumps on your skin?
- Do you have a soft lump under your skin?
- Do you have a neck lump?
Treatment of Kimura's Disease
Because the disease is so rare, there is no standard protocol for management of this condition. However, a combination of surgery, radiation therapy, and medications can be used to remove or shrink the masses.
Reviewed By:
Caroline M. Doan, DO (Internal Medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Feb 13, 2025
Following the Medical Content Editorial Policy
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With a free 3-min Kimura's Disease quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.
This questionnaire is customized to your situation and symptoms, including the following personal information:
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Scars or marks from the rash/wound
- Swollen lymph nodes above collar bone
- Lumps under skin
- Swollen armpit
- Hard fingertips
- Swollen lymph nodes continue to grow larger
- Lump behind the neck
- It moves when I touch the lump
- Reddish skin lumps
- Tightening of the skin of the fingers
- Multiple lymph nodes swollen in my groin
- Lymph nodes in the groin are swollen
- Scar formation after the rash
- Bumps on my arm
- Swollen lymph nodes in the armpit
See full list
Symptoms Related to Kimura's Disease
Diseases Related to Kimura's Disease
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Shetty AK, Beaty MW, McGuirt WF Jr, Woods CR, Givner LB. Kimura's disease: a diagnostic challenge. Pediatrics. 2002 Sep;110(3):e39. doi: 10.1542/peds.110.3.e39. PMID: 12205289.
https://pubmed.ncbi.nlm.nih.gov/12205289/Thomas J, Jayachandran NV, Chandrasekhara PK, Rajasekhar L, Narsimulu G. Kimura's disease--an unusual cause of lymphadenopathy in children. Clin Rheumatol. 2008 May;27(5):675-7. doi: 10.1007/s10067-007-0821-9. Epub 2008 Feb 2. PMID: 18246382.
https://pubmed.ncbi.nlm.nih.gov/18246382/Mrówka-Kata K, Kata D, Kyrcz-Krzemień S, Helbig G. Kikuchi-Fujimoto and Kimura diseases: the selected, rare causes of neck lymphadenopathy. Eur Arch Otorhinolaryngol. 2010 Jan;267(1):5-11. doi: 10.1007/s00405-009-1120-7. Epub 2009 Oct 16. PMID: 19834725.
https://pubmed.ncbi.nlm.nih.gov/19834725/