Mixed Connective Tissue Disease Quiz
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Reviewed By:
Kaito Nakamura, MD (Rheumatology & Allergy)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
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With an easy 3-min questionnaire, Ubie's AI-powered system will generate a free report on possible causes.
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Mixed connective tissue disease as well as similar diseases can be checked at the same time.
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People with these symptoms also use Ubie's symptom checker to find possible causes
Raynaud's
Discoloration of the fingers
My hands turned white then purple
The fingers/toes turning white
Eye strain
Hand color changes in cold places
Hand turns pale in cold places
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Learn more about Mixed connective tissue disease
Content updated on Sep 20, 2022
What is mixed connective tissue disease?
Mixed connective tissue disease (MCTD) is a rare autoimmune disorder where the immune system mistakenly attacks the body's own tissues. Risk factors include family history of connective tissue disease and exposure to certain viruses or chemicals. It's most common in women in their 20s and 30s, but children may also be affected.
Symptoms of mixed connective tissue disease
Fingers and toes turn from pale blue to purplish-red when in the cold
Upper jaw pain
Facial pain
Joints feel warm
Feeling breathless
Skin over my fingers are hardened
Fever
Questions your doctor may ask to check for mixed connective tissue disease
Your doctor may ask these questions to diagnose mixed connective tissue disease
Have you ever experienced your fingers and toes turning from blue to purple or red in a cold environment?
Do you have upper jaw pain?
Do you have pain in the face?
Are your joints hot to touch?
Are you breathless or having hard time breathing?
Treatment for mixed connective tissue disease
There is no cure for mixed connective tissue disease (MCTD). However, it can be controlled with medication to suppress the immune cells, which is effective especially if diagnosed early.
View the symptoms of Mixed connective tissue disease
Diseases related to Mixed connective tissue disease
References
Alves MR, Isenberg DA. "Mixed connective tissue disease": a condition in search of an identity. Clin Exp Med. 2020 May;20(2):159-166. doi: 10.1007/s10238-020-00606-7. Epub 2020 Mar 4. PMID: 32130548; PMCID: PMC7181542.
https://link.springer.com/article/10.1007/s10238-020-00606-7
Pepmueller PH. Undifferentiated Connective Tissue Disease, Mixed Connective Tissue Disease, and Overlap Syndromes in Rheumatology. Mo Med. 2016 Mar-Apr;113(2):136-40. PMID: 27311225; PMCID: PMC6139943.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139943/
Ortega-Hernandez OD, Shoenfeld Y. Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment. Best Pract Res Clin Rheumatol. 2012 Feb;26(1):61-72. doi: 10.1016/j.berh.2012.01.009. PMID: 22424193.
https://www.sciencedirect.com/science/article/abs/pii/S1521694212000101?via%3Dihub
Perelas A, Arrossi AV, Highland KB. Pulmonary Manifestations of Systemic Sclerosis and Mixed Connective Tissue Disease. Clin Chest Med. 2019 Sep;40(3):501-518. doi: 10.1016/j.ccm.2019.05.001. Epub 2019 Jul 6. PMID: 31376887.
https://www.sciencedirect.com/science/article/abs/pii/S0272523119300292?via%3Dihub
Berard RA, Laxer RM. Pediatric Mixed Connective Tissue Disease. Curr Rheumatol Rep. 2016 May;18(5):28. doi: 10.1007/s11926-016-0576-x. PMID: 27032791.
https://link.springer.com/article/10.1007/s11926-016-0576-x
User testimonials
Reviewed By:
Kaito Nakamura, MD (Rheumatology & Allergy)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Just 3 minutes.
Developed by doctors.
Ubie is supervised by 50+ medical experts worldwide
Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan