Mixed Connective Tissue Disease Quiz
Check your symptoms and
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Reviewed By:
Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.
Kaito Nakamura, MD (Rheumatology)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Cold fingers/toes
Upper jaw hurts
Have facial pain
Burning sensation in the joints
Shortness of breath
Hard fingertips
Have a fever
Not seeing your symptoms? No worries!
How Ubie Can Help You
With a free 3-min Mixed Connective Tissue Disease quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.
This questionnaire is customized to your situation and symptoms, including the following personal information:
Biological Sex - helps us provide relevant suggestions for male vs. female conditions.
Age - adjusts our guidance based on any age-related health factors.
History - considers past illnesses, surgeries, family history, and lifestyle choices.
Your symptoms
Our AI
Your report
Your personal report will tell you
✔ When to see a doctor
✔︎ What causes your symptoms
✔︎ Treatment information etc.
People with similar symptoms also use Ubie's symptom checker to find possible causes
- Raynaud's
- Eye strain
- Discoloration of the fingers
- One or more joints feel warm
- Hand color changes in cold places
- Hand turns pale in cold places
- Pain in cheek
- Raynaud syndrome
- White finger
- Knees hot, no pain
- Raynaud's phenomenon
- Pain in my sinuses below the eyes
- Joint pain and redness
- Pain in the upper jaw
- Face pain when I look down
See full list
Just 3 minutes.
Developed by doctors.
Try Free Symptom QuizWhat is Mixed Connective Tissue Disease?
Mixed connective tissue disease (MCTD) is a rare autoimmune disorder where the immune system mistakenly attacks the body's own tissues. Risk factors include family history of connective tissue disease and exposure to certain viruses or chemicals. It's most common in women in their 20s and 30s, but children may also be affected.
Typical Symptoms of Mixed Connective Tissue Disease
- Fingers and toes turn from pale blue to purplish-red when in the cold
- Upper jaw pain
- Facial pain
- Joints feel warm
- Skin over my fingers are hardened
- Fever
- Feels a hard lump in upper right abdomen
- Feeling breathless
Diagnostic Questions for Mixed Connective Tissue Disease
Your doctor may ask these questions to check for this disease:
- Do your fingers and toes turn from pale blue to purplish-red color in the cold?
- Do you have pain in your upper jaw?
- Do you have facial pain?
- Are your joints hot?
- Is your skin getting harder from fingertip to back of your hand?
Treatment of Mixed Connective Tissue Disease
There is no cure for mixed connective tissue disease (MCTD). However, disease progression and symptoms can be controlled with medication to suppress the immune cells and block inflammation.
Think you might have
Mixed Connective Tissue Disease?
Try a symptom check testSymptoms Related to Mixed Connective Tissue Disease
Diseases Related to Mixed Connective Tissue Disease
References
Alves MR, Isenberg DA. "Mixed connective tissue disease": a condition in search of an identity. Clin Exp Med. 2020 May;20(2):159-166. doi: 10.1007/s10238-020-00606-7. Epub 2020 Mar 4. PMID: 32130548; PMCID: PMC7181542.
https://link.springer.com/article/10.1007/s10238-020-00606-7Pepmueller PH. Undifferentiated Connective Tissue Disease, Mixed Connective Tissue Disease, and Overlap Syndromes in Rheumatology. Mo Med. 2016 Mar-Apr;113(2):136-40. PMID: 27311225; PMCID: PMC6139943.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139943/Ortega-Hernandez OD, Shoenfeld Y. Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment. Best Pract Res Clin Rheumatol. 2012 Feb;26(1):61-72. doi: 10.1016/j.berh.2012.01.009. PMID: 22424193.
https://www.sciencedirect.com/science/article/abs/pii/S1521694212000101?via%3DihubPerelas A, Arrossi AV, Highland KB. Pulmonary Manifestations of Systemic Sclerosis and Mixed Connective Tissue Disease. Clin Chest Med. 2019 Sep;40(3):501-518. doi: 10.1016/j.ccm.2019.05.001. Epub 2019 Jul 6. PMID: 31376887.
https://www.sciencedirect.com/science/article/abs/pii/S0272523119300292?via%3DihubBerard RA, Laxer RM. Pediatric Mixed Connective Tissue Disease. Curr Rheumatol Rep. 2016 May;18(5):28. doi: 10.1007/s11926-016-0576-x. PMID: 27032791.
https://link.springer.com/article/10.1007/s11926-016-0576-x
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Male, 30s
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(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
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Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
(Sep 26, 2024)
Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.
Kaito Nakamura, MD (Rheumatology)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Think you might have
Mixed Connective Tissue Disease?
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Link to full study:
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