Mycosis Fungoides / Sézary Syndrome Quiz
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Redness of the skin
Hard reddish-brown lumps
Swelling
Itchy
My skin is dry
Red spots on skin
Hard reddish-brown bumps
Not seeing your symptoms? No worries!
What is Mycosis Fungoides / Sézary Syndrome?
Mycosis fungoides and Sezary syndrome are types of cutaneous (skin) T-cell lymphoma. These are cancers of lymphocytes, a type of white blood cell in the immune system, go onto affect the skin. In Sézary syndrome specifically, cancer cells are also found in the blood. Both men and women can be affected, and those over 50 years of age are at higher risk as are people with HIV infections.
Typical Symptoms of Mycosis Fungoides / Sézary Syndrome
- Skin over the entire body is red
- Hair loss
- Reddish-brown hard lumps or bumps on the skin
- Itchy skin
- Swollen lymph nodes or lumps in the neck, armpits, groin, or behind the ears
- Dry and flaky skin
- Skin problem on the chest, tummy or back
- Multiple areas of skin redness or red spots
Diagnostic Questions for Mycosis Fungoides / Sézary Syndrome
Your doctor may ask these questions to check for this disease:
- Is your whole body red?
- Are you experiencing increased hair loss?
- Do you have hard, reddish-brown skin lumps or bumps?
- Do you have itchy skin?
- Do you have any swollen lymph nodes or lumps in your neck, armpits, groin, or behind your ears?
Treatment of Mycosis Fungoides / Sézary Syndrome
Treatment depends on the disease subtype, extent, stage, and other factors. Options include a form of light therapy called photodynamic therapy, specialized radiotherapy aimed either at individual spots or the whole body, chemotherapy, immunotherapies, surgery, and new targeted drug therapies.
Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Dec 5, 2025
Following the Medical Content Editorial Policy
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Mycosis Fungoides / Sézary Syndrome?
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Loss of hair
- Thinning hair
- Lymph swollen
- Bald spots
- The skin is itchy and has scratches
- Patchy hair loss
- Swollen lymph nodes above collar bone
- Receding hairline
- Skin itching that worsens at night
- Before the hair loss, the scalp was itchy
- No new hair growth
- Swollen armpit
- Itch is mild
- Scalp itch or discomfort, followed by hair falling out
- Front part of the hairline is moving back
See full list
Symptoms Related to Mycosis Fungoides / Sézary Syndrome
Diseases Related to Mycosis Fungoides / Sézary Syndrome
FAQs
Q.
Is it Carcinoma? Why Your Cells are Mutating and Medically Approved Next Steps to Take Now
A.
Carcinoma is a common cancer that starts in epithelial cells of the skin, organs, and glands; DNA mutations from aging, UV exposure, tobacco, infections, chemicals, chronic inflammation, hormones, or inherited changes can drive it, though many suspicious findings turn out to be benign. The only way to know is prompt medical evaluation and often a biopsy, along with documenting symptoms, following screening, and reducing risks now. There are several factors to consider, and critical details that could change your next steps, including red flags and treatment pathways, are explained below.
References:
* Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013. PMID: 22114187.
* Negrini S, Gorgoulis VG, Halazonetis TD. Genomic instability in cancer: Insights into its causes and consequences. Nat Rev Mol Cell Biol. 2020 Dec;21(12):737-752. doi: 10.1038/s41580-020-0288-5. PMID: 32943729.
* Patel M, Kim H, Marini R, Senger K, Li A, Park H, Zhang S, Hu J. Early detection of cancer: current challenges and future directions. Transl Res. 2021 Jul;233:23-41. doi: 10.1016/j.trsl.2021.03.003. Epub 2021 Mar 18. PMID: 34211139.
* Smith RA, Andrews KS, Brooks D, DeSantis CE, Fedewa SA, Wolf AMD, Wender RC. Cancer screening in the United States, 2019: A review of current guideline-based recommendations and issues in personalized screening. CA Cancer J Clin. 2019 Jul;69(4):279-299. doi: 10.3322/caac.21559. Epub 2019 Jun 26. PMID: 31338505.
* Vilar E, Mullamitha S, Stamp G. Molecular diagnostics in cancer: a review. Future Oncol. 2018 Apr;14(8):799-813. doi: 10.2217/fon-2017-0628. Epub 2018 Mar 28. PMID: 29598270.
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Mycosis Fungoides (Including Sézary Syndrome) Treatment (PDQ®) – Patient Version
https://www.cancer.gov/types/lymphoma/patient/mycosis-fungoides-treatment-pdq#:~:text=Key%20Points,red%20rash%20on%20the%20skin.MYCOSIS FUNGOIDES - Cutaneous Lymphoma Foundation
https://www.clfoundation.org/mycosis-fungoides