Nephrotic Syndrome Quiz

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Yoshinori Abe, MD (Internal medicine)

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Learn more about Nephrotic syndrome

Content updated on Sep 20, 2022

What is nephrotic syndrome?

A condition in which the kidneys are damaged and leak protein. Common causes are autoimmune (body's immune system attacks itself) and diabetic kidney disease.

Symptoms of nephrotic syndrome

  • Facial swelling

  • Swelling of any body part

  • Swollen eyelids

  • Swollen legs / fluid retention in the legs

  • Swelling of the arms or hands

  • Frothy urine

  • Unintentional weight gain of more than 2 kg/month

  • Feeling breathless

Questions your doctor may ask to check for nephrotic syndrome

Your doctor may ask these questions to diagnose nephrotic syndrome

  • Do you have facial swelling?

  • Do you have any swelling in any part of your body?

  • Do you have puffy eyelids?

  • Do you have swollen legs?

  • Do you have swelling in your hands or arms?

Treatment for nephrotic syndrome

Treatment depends on the cause and degree of kidney damage. If this is caused by the immune system, the specialist may prescribe immune-suppressing medications. Medications to protect the kidneys and reduce water retention may also be given.

View the symptoms of Nephrotic syndrome


  • Wang CS, Greenbaum LA. Nephrotic Syndrome. Pediatr Clin North Am. 2019 Feb;66(1):73-85. doi: 10.1016/j.pcl.2018.08.006. PMID: 30454752.

  • Politano SA, Colbert GB, Hamiduzzaman N. Nephrotic Syndrome. Prim Care. 2020 Dec;47(4):597-613. doi: 10.1016/j.pop.2020.08.002. Epub 2020 Sep 26. PMID: 33121631.

  • Downie ML, Gallibois C, Parekh RS, Noone DG. Nephrotic syndrome in infants and children: pathophysiology and management. Paediatr Int Child Health. 2017 Nov;37(4):248-258. doi: 10.1080/20469047.2017.1374003. Epub 2017 Sep 15. PMID: 28914167.

  • Liebeskind DS. Nephrotic syndrome. Handb Clin Neurol. 2014;119:405-15. doi: 10.1016/B978-0-7020-4086-3.00026-6. PMID: 24365309.

  • Shin JI, Kronbichler A, Oh J, Meijers B. Nephrotic Syndrome: Genetics, Mechanism, and Therapies. Biomed Res Int. 2018 Jan 28;2018:6215946. doi: 10.1155/2018/6215946. PMID: 29670902; PMCID: PMC5833294.

Reviewed By:

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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