Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis Quiz
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There is a lump
I have left lower abdominal pain
Lumps under skin
Pain specific to the lower left side of the abdomen
Cysts under skin
Pain in the lower left stomach
There is a nodule in the groin
Not seeing your symptoms? No worries!
What is Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis?
Pancreatic panniculitis is a rare type of inflammation of the deepest fat layer of the skin, causing cell death. The exact cause is unknown, but it could be due to an excess of enzymes produced by the pancreas as a result of pancreatic disease.
Typical Symptoms of Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis
- Skin lumps
- Pain in the lower left abdomen
- Fever
- Greasy stools that float, associated with problems with digestion
- Pain on one side of the abdomen
- Skin problems
- Stomach or abdominal pain
- Joint pain, swelling, or discomfort
Diagnostic Questions for Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis
Your doctor may ask these questions to check for this disease:
- Have you noticed any lumps on your skin?
- Do you feel pain in your lower left abdomen?
- Do you have a fever?
- Are your stools greasy and smelly?
- Do you feel pain on one side of your abdomen?
Treatment of Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis
Treating pancreatic panniculitis involves addressing the underlying pancreatic disease, which may require surgical or medical management. The lesions typically heal on their own afterward.
Reviewed By:
Sarita Nori, MD (Dermatology)
Dr. Sarita Nori was drawn to dermatology because of the intersection of science and medicine that is at the heart of dermatology. She feels this is what really allows her to help her patients. “There is a lot of problem-solving in dermatology and I like that,” she explains. “It’s also a profession where you can help people quickly and really make a difference in their lives.” | Some of the typical skin problems that Dr. Nori treats include skin cancers, psoriasis, acne, eczema, rashes, and contact dermatitis. Dr Nori believes in using all possible avenues of treatment, such as biologics, especially in patients with chronic diseases such as eczema and psoriasis. “These medications can work superbly, and they are really life-changing for many patients.” | Dr. Nori feels it’s important for patients to have a good understanding of the disease or condition that is affecting them. “I like to educate my patients on their problem and have them really understand it so they can take the best course of action. Patients always do better when they understand their skin condition, and how to treat it.”
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Feb 19, 2025
Following the Medical Content Editorial Policy
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Pancreatic Panniculitis / Subcutaneous Nodular Fat Necrosis?
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Seguí M, Rodríguez-Jiménez P, Fraga J, Navas J, Ríos JJ, Revilla D, Santos-Briz Á, Lluch JJ, Fernández Figueras MT, Luque M, Llamas Velasco M (2021). Pancreatic panniculitis revisited: A series of 34 patients. Journal of cutaneous pathology.
https://pubmed.ncbi.nlm.nih.gov/37605438/Kasamatsu H, Oyama N, Hasegawa M, Oku Y, Inoue G, Kimura M, Kanno M, Kawakami T, Ohta H, Yoneshima M (2020). Fatal case of pancreatic panniculitis caused by occult neuroendocrine tumor in the corresponding organ: A case report and review of the published work. The Journal of dermatology.
https://pubmed.ncbi.nlm.nih.gov/33073392/Bernacka M, Kosztowny K, Schwartz RA, Hogendorf P, Bogaczewicz J, Woźniacka A (2021). The Pancreatitis, Panniculitis, and Polyarthritis (PPP) Syndrome: Subcutaneous Nodular Fat Necrosis, a Cutaneous Marker of Pancreatic Neoplasia. Acta dermatovenerologica Croatica : ADC.
https://pubmed.ncbi.nlm.nih.gov/34477064/