Subacute Cerebellar Degeneration Quiz
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Hard to walk
My hands and feet are clumsy
Speech not fluent
Have nausea
Difficulty rising from the sitting position
Spinning feeling
Tingling
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What is Subacute Cerebellar Degeneration?
Subacute cerebellar degeneration (SCD) is characterized by loss of brain cells from the cerebellum, which controls balance and coordination of movements. SCD can be caused by inherited genetic mutations, alcohol abuse, vitamin deficiencies, certain brain infections, brain tumors, or autoimmune disorders such as mutiple sclerosis, celiac disease, Sjogren syndrome, and paraneoplastic syndromes, which are rare, abnormal immune responses to cancerous tumors.
Typical Symptoms of Subacute Cerebellar Degeneration
- Difficulty walking normally
- Difficulty speaking clearly
- Difficulty with fine motor control or coordination in hands and feet
- Difficulty standing up from sitting position
- I feel like I'm spinning around / vertigo
- Unable to speak or using incorrect words
- Uncontrollable movements
- History of cancer
Diagnostic Questions for Subacute Cerebellar Degeneration
Your doctor may ask these questions to check for this disease:
- Do you have difficulty walking normally?
- Are you having difficulty speaking clearly?
- Do you have difficulty with fine motor control or coordination in your hands and feet?
- Is it hard for you to get up from a chair by yourself?
- Do you feel like your surroundings are spinning?
Treatment of Subacute Cerebellar Degeneration
There is no cure for most forms of SCD, although medications to reduce immune system activity can be given in cases of SCD due to autoimmune causes. Treatment is otherwise typically supportive, and includes physical and occupational therapy tailored to individual symptoms.
Reviewed By:
Benjamin Kummer, MD (Neurology)
Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
Content updated on Jan 14, 2025
Following the Medical Content Editorial Policy
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- Walking difficulties
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- Can't get up from chair
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- Abnormal gait
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- Shuffle when I walk
- Difficulty walking in a straight line with one foot directly in front of the other
- Difficulty standing up from sitting position
- Slurred speech
- Gait is too unstable to walk following a straight line (e.g. like a tightrope)
- Waddling gait
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Symptoms Related to Subacute Cerebellar Degeneration
Diseases Related to Subacute Cerebellar Degeneration
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Jones AL, Flanagan EP, Pittock SJ, Mandrekar JN, Eggers SD, Ahlskog JE, McKeon A. Responses to and Outcomes of Treatment of Autoimmune Cerebellar Ataxia in Adults. JAMA Neurol. 2015 Nov;72(11):1304-12. doi: 10.1001/jamaneurol.2015.2378. PMID: 26414229.
https://jamanetwork.com/journals/jamaneurology/fullarticle/2444311Bolla L, Palmer RM. Paraneoplastic cerebellar degeneration. Case report and literature review. Arch Intern Med. 1997 Jun 9;157(11):1258-62. doi: 10.1001/archinte.157.11.1258. PMID: 9183238.
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/623396Ilg W, Synofzik M, Brötz D, Burkard S, Giese MA, Schöls L. Intensive coordinative training improves motor performance in degenerative cerebellar disease. Neurology. 2009 Dec 1;73(22):1823-30. doi: 10.1212/WNL.0b013e3181c33adf. Epub 2009 Oct 28. PMID: 19864636.
https://n.neurology.org/content/73/22/1823