Subacute Cerebellar Degeneration (Note the Presence of Malignant Tumors) Quiz

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Benjamin Kummer, MD

Benjamin Kummer, MD (Neurology)

Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

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Content updated on Apr 4, 2024

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People with similar symptoms also use Ubie's symptom checker to find possible causes

  • Abnormal gait

  • Shuffle when I walk

  • Difficulty walking in a straight line with one foot directly in front of the other

  • Trouble standing

  • Transient gait disturbance

  • Walking difficulties

  • Can't speak clearly

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What is Subacute Cerebellar Degeneration (Note the Presence of Malignant Tumors)?

Subacute cerebellar degeneration (SCD) is characterized by loss of brain cells from the cerebellum, which controls balance and coordination of movements. SCD can be caused by inherited genetic mutations, alcohol abuse, vitamin deficiencies, certain brain infections, brain tumors, or autoimmune disorders such as mutiple sclerosis, celiac disease, Sjogren syndrome, and paraneoplastic syndromes, which are rare, abnormal immune responses to cancerous tumors.

Typical Symptoms of Subacute Cerebellar Degeneration (Note the Presence of Malignant Tumors)

  • Difficulty in walking

  • Hands and legs became clumsy - I cannot do fine work with them

  • Slurred speech

  • Difficulty standing up from sitting position

  • I feel like I'm spinning around / vertigo

  • Unable to speak or using incorrect words

  • Uncontrollable movements

  • History of cancer

Doctor's Diagnostic Questionson Subacute Cerebellar Degeneration (Note the Presence of Malignant Tumors)

Your doctor may ask these questions to check for this disease:

  • Is walking difficult for you?

  • Are your movements and coordination feeling more difficult or clumsy lately?

  • Is your speech slurred?

  • Is it hard for you to get up from a chair by yourself?

  • Do you feel like your surroundings are spinning?

Treatmentof Subacute Cerebellar Degeneration (Note the Presence of Malignant Tumors)

There is no cure for most forms of SCD, although medications to reduce immune system activity can be given in cases of SCD due to autoimmune causes. Treatment is otherwise typically supportive, and includes physical and occupational therapy tailored to individual symptoms.

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References

  • Jones AL, Flanagan EP, Pittock SJ, Mandrekar JN, Eggers SD, Ahlskog JE, McKeon A. Responses to and Outcomes of Treatment of Autoimmune Cerebellar Ataxia in Adults. JAMA Neurol. 2015 Nov;72(11):1304-12. doi: 10.1001/jamaneurol.2015.2378. PMID: 26414229.

    https://jamanetwork.com/journals/jamaneurology/fullarticle/2444311

  • Bolla L, Palmer RM. Paraneoplastic cerebellar degeneration. Case report and literature review. Arch Intern Med. 1997 Jun 9;157(11):1258-62. doi: 10.1001/archinte.157.11.1258. PMID: 9183238.

    https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/623396

  • Ilg W, Synofzik M, Brötz D, Burkard S, Giese MA, Schöls L. Intensive coordinative training improves motor performance in degenerative cerebellar disease. Neurology. 2009 Dec 1;73(22):1823-30. doi: 10.1212/WNL.0b013e3181c33adf. Epub 2009 Oct 28. PMID: 19864636.

    https://n.neurology.org/content/73/22/1823

User Testimonials

Reviewed By:

Benjamin Kummer, MD

Benjamin Kummer, MD (Neurology)

Dr Kummer is Assistant Professor of Neurology at the Icahn School of Medicine at Mount Sinai (ISMMS), with joint appointment in Digital and Technology Partners (DTP) at the Mount Sinai Health System (MSHS) as Director of Clinical Informatics in Neurology. As a triple-board certified practicing stroke neurologist and informaticist, he has successfully improved clinical operations at the point of care by acting as a central liaison between clinical neurology faculty and DTP teams to implement targeted EHR configuration changes and workflows, as well as providing subject matter expertise on health information technology projects across MSHS. | Dr Kummer also has several years’ experience building and implementing several informatics tools, presenting scientific posters, and generating a body of peer-reviewed work in “clinical neuro-informatics” – i.e., the intersection of clinical neurology, digital health, and informatics – much of which is centered on digital/tele-health, artificial intelligence, and machine learning. He has spearheaded the Clinical Neuro-Informatics Center in the Department of Neurology at ISMMS, a new research institute that seeks to establish the field of clinical neuro-informatics and disseminate knowledge to the neurological community on the effects and benefits of clinical informatics tools at the point of care.

Shohei Harase, MD

Shohei Harase, MD (Neurology)

Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.

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