Myasthenia Gravis Quiz
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Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Learn more about Myasthenia gravis
Content updated on Sep 20, 2022
What is myasthenia gravis?
A condition where there is a breakdown in the normal communication between nerves and muscles, resulting in muscle weakness and easy fatigability. It is caused by abnormal immune reaction where your immune system produces antibodies that mistakenly attacks healthy parts of the body.
Symptoms of myasthenia gravis
Muscle weakness that is worse at the end of the day
Repeated motions causes weakness which improves after rest
Drooping eyelids
Fatigue
Double vision
Numbness or abnormal sensation
Hoarseness of voice worst in the evenings and nights
Poor vision
Questions your doctor may ask to check for myasthenia gravis
Your doctor may ask these questions to diagnose myasthenia gravis
Do you feel more fatigued and unable to move your muscles in the evenings compared to the mornings?
Have you ever felt gradually unable to move after a repetitive action such as brushing your teeth, then being able to move again after some rest?
Do you have drooping of the eyelid(s) that sometimes cover part of the eye?
Do you feel fatigued?
Do you have double vision?
Treatment for myasthenia gravis
There is no cure for myasthenia gravis, but various treatments, used alone or in combination are available to relieve symptoms . Medications to reduce symptoms, suppress the abnormal immune reaction and improve muscle contraction are prescribed, as well as physiotherapy. Myasthenia gravis is also associated with tumors in the thymus gland, which can be surgically removed.
View the symptoms of Myasthenia gravis
Diseases related to Myasthenia gravis
References
Gilhus NE, Verschuuren JJ. Myasthenia gravis: subgroup classification and therapeutic strategies. Lancet Neurol. 2015 Oct;14(10):1023-36. doi: 10.1016/S1474-4422(15)00145-3. PMID: 26376969.
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(15)00145-3/fulltext
Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol. 2014 Mar;175(3):408-18. doi: 10.1111/cei.12217. PMID: 24117026; PMCID: PMC3927901.
https://academic.oup.com/cei/article/175/3/408/6421208
Gilhus NE. Myasthenia Gravis. N Engl J Med. 2016 Dec 29;375(26):2570-2581. doi: 10.1056/NEJMra1602678. PMID: 28029925.
https://www.nejm.org/doi/10.1056/NEJMra1602678
Peragallo JH. Pediatric Myasthenia Gravis. Semin Pediatr Neurol. 2017 May;24(2):116-121. doi: 10.1016/j.spen.2017.04.003. Epub 2017 Apr 7. PMID: 28941526.
https://www.sciencedirect.com/science/article/abs/pii/S1071909117300633?via%3Dihub
Mantegazza R, Bernasconi P, Cavalcante P. Myasthenia gravis: from autoantibodies to therapy. Curr Opin Neurol. 2018 Oct;31(5):517-525. doi: 10.1097/WCO.0000000000000596. PMID: 30156572.
https://journals.lww.com/co-neurology/Abstract/2018/10000/Myasthenia_gravis__from_autoantibodies_to_therapy.3.aspx
Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan