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Published on: 3/5/2025

What Conditions Should Be Considered If Heavy Menstrual Bleeding Persists?

Heavy menstrual bleeding, also known as menorrhagia, can be a significant concern for many women. If this condition persists, it is essential to consider various underlying causes to ensure appropriate diagnosis and management.

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Explanation

Uterine Causes

  • Uterine Fibroids: These benign tumors can cause heavy bleeding due to their size and location within the uterus.
  • Endometrial Polyps: These growths on the inner lining of the uterus can lead to abnormal bleeding.
  • Adenomyosis: This condition occurs when the endometrial tissue grows into the muscular wall of the uterus, often resulting in heavy and painful periods.
  • Endometrial Hyperplasia: Thickening of the uterine lining can lead to heavy bleeding and may be a precursor to endometrial cancer.

Hormonal Imbalances

  • Polycystic Ovary Syndrome (PCOS): This condition can cause irregular menstrual cycles and heavy bleeding due to hormonal imbalances.
  • Thyroid Disorders: Both hyperthyroidism and hypothyroidism can affect menstrual patterns and lead to heavy bleeding.

Coagulation Disorders

  • Von Willebrand Disease: This genetic disorder affects blood clotting and can lead to heavy menstrual bleeding.
  • Other Bleeding Disorders: Conditions such as platelet function disorders or clotting factor deficiencies can also result in abnormal bleeding.

Infections

  • Pelvic Inflammatory Disease (PID): Infections of the reproductive organs can cause abnormal bleeding and should be considered, especially if accompanied by pain or fever.

Malignancies

  • Endometrial Cancer: Persistent heavy bleeding, especially in women over 40 or those with risk factors, should raise suspicion for endometrial cancer.
  • Cervical Cancer: Abnormal bleeding can also be a symptom of cervical cancer, particularly if there are other concerning signs.

When to Seek Medical Attention

If heavy menstrual bleeding persists, it is crucial to consult a healthcare provider, especially if:

  • The bleeding is soaking through one or more pads or tampons every hour for several hours.
  • There are accompanying symptoms such as severe pain, dizziness, or fatigue.
  • There are changes in menstrual patterns or bleeding between periods.

What to Expect at the Appointment

During your visit, the healthcare provider will likely:

  • Take a Detailed Medical History: Discuss your menstrual cycle, any associated symptoms, and medical history.
  • Perform a Physical Examination: This may include a pelvic exam to assess for any abnormalities.
  • Order Diagnostic Tests: Blood tests, ultrasound, or endometrial biopsy may be necessary to determine the underlying cause of heavy bleeding.

(References)

  • Brenner PF. Differential diagnosis of abnormal uterine bleeding. Am J Obstet Gynecol. 1996 Sep;175(3 Pt 2):766-9. doi: 10.1016/s0002-9378(96)80082-2. PMID: 8828559.

  • Borzutzky C, Jaffray J. Diagnosis and Management of Heavy Menstrual Bleeding and Bleeding Disorders in Adolescents. JAMA Pediatr. 2020 Feb 1;174(2):186-194. doi: 10.1001/jamapediatrics.2019.5040. PMID: 31886837.

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