Acute HIV Infection Quiz

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Saqib Baig

Saqib Baig, MD, MS (Respiratory medicine, Critical Care, Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Acute HIV infection

Content updated on Sep 20, 2022

What is acute HIV infection?

Acute HIV infection occurs in some individuals during the first 4 weeks after contracting the HIV virus. The virus rapidly attacks the immune cells and causes fevers, headaches, and sometimes a rash. The patient is highly contagious during this time as the viral load is high. Risk factors for transmitting HIV include unprotected sexual activity and contaminated needle stick injuries(e.g., via tattoos or sharing needles). Rarely, it is transmitted through the transfusion of blood products.

Symptoms of acute HIV infection

  • Repeated episodes of fever above 100.4°F / 38°C

  • Fever

  • Joint pain even when resting

  • History of HIV or AIDS

  • Headache

  • Dry cough

  • My brain is not functioning right now

Questions your doctor may ask to check for acute HIV infection

Your doctor may ask these questions to diagnose acute HIV infection

  • Have you had repeated fevers of 100.4°F / 38°C or higher?

  • Do you have a fever?

  • Do you have joint pain even when you are at rest?

  • Have you been diagnosed with HIV or AIDS?

  • Do you have headaches or does your head feel heavy?

Treatment for acute HIV infection

Lifelong antiretroviral therapy is effective in controlling HIV, reducing the viral load, preventing transmission, and suppressing viral multiplication. Early diagnosis and treatment are highly beneficial.

View the symptoms of Acute HIV infection


  • Robb ML, Ananworanich J. Lessons from acute HIV infection. Curr Opin HIV AIDS. 2016 Nov;11(6):555-560. doi: 10.1097/COH.0000000000000316. PMID: 27716734; PMCID: PMC5642316.

  • Qadir MI, Abid A. Acute HIV Infection: Advances in Mechanisms and Prophylactic Therapeutic Management. Crit Rev Eukaryot Gene Expr. 2017;27(1):79-90. doi: 10.1615/CritRevEukaryotGeneExpr.2017019467. PMID: 28436334.,7963fdcd2773abac,0b34160b534116b0.html

Reviewed By:

Saqib Baig

Saqib Baig, MD, MS (Respiratory medicine, Critical Care, Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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