Alport Syndrome Quiz

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Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Alport syndrome

Content updated on Nov 2, 2022

What is alport syndrome?

A rare genetic disorder characterized by progressive kidney disease and abnormalities of the inner ear and the eye.

Symptoms of alport syndrome

  • Bloody or red urine

Questions your doctor may ask to check for alport syndrome

Your doctor may ask these questions to diagnose alport syndrome

  • Have you ever had red or brown urine (hematuria)?

Treatment for alport syndrome

The treatment is directed toward the specific symptoms that are apparent in each individual. Angiotensin-converting enzyme (ACE inhibitor) therapy or angiotensin receptor blockers (ARB) therapy may reduce protein in urine and the progression of kidney disease.

View the symptoms of Alport syndrome

  • Blood in urine

References

  • Kashtan CE. Alport Syndrome: Achieving Early Diagnosis and Treatment. Am J Kidney Dis. 2021 Feb;77(2):272-279. doi: 10.1053/j.ajkd.2020.03.026. Epub 2020 Jul 22. PMID: 32712016.

    https://www.ajkd.org/article/S0272-6386(20)30734-4/fulltext

  • Nozu K, Nakanishi K, Abe Y, Udagawa T, Okada S, Okamoto T, Kaito H, Kanemoto K, Kobayashi A, Tanaka E, Tanaka K, Hama T, Fujimaru R, Miwa S, Yamamura T, Yamamura N, Horinouchi T, Minamikawa S, Nagata M, Iijima K. A review of clinical characteristics and genetic backgrounds in Alport syndrome. Clin Exp Nephrol. 2019 Feb;23(2):158-168. doi: 10.1007/s10157-018-1629-4. Epub 2018 Aug 20. PMID: 30128941; PMCID: PMC6510800.

    https://link.springer.com/article/10.1007/s10157-018-1629-4

  • Savige J, Ariani F, Mari F, Bruttini M, Renieri A, Gross O, Deltas C, Flinter F, Ding J, Gale DP, Nagel M, Yau M, Shagam L, Torra R, Ars E, Hoefele J, Garosi G, Storey H. Expert consensus guidelines for the genetic diagnosis of Alport syndrome. Pediatr Nephrol. 2019 Jul;34(7):1175-1189. doi: 10.1007/s00467-018-3985-4. Epub 2018 Jul 9. PMID: 29987460.

    https://link.springer.com/article/10.1007/s00467-018-3985-4

  • Torra R, Furlano M. New therapeutic options for Alport syndrome. Nephrol Dial Transplant. 2019 Aug 1;34(8):1272-1279. doi: 10.1093/ndt/gfz131. PMID: 31190059.

    https://academic.oup.com/ndt/article/34/8/1272/5514265

Reviewed By:

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD

Neurology

Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD

Psychiatry

Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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