Alport Syndrome Quiz
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Learn more about Alport syndrome
Content updated on Nov 2, 2022
What is alport syndrome?
A rare genetic disorder characterized by progressive kidney disease and abnormalities of the inner ear and the eye.
Symptoms of alport syndrome
Bloody or red urine
Questions your doctor may ask to check for alport syndrome
Your doctor may ask these questions to diagnose alport syndrome
Have you ever had red or brown urine (hematuria)?
Treatment for alport syndrome
The treatment is directed toward the specific symptoms that are apparent in each individual. Angiotensin-converting enzyme (ACE inhibitor) therapy or angiotensin receptor blockers (ARB) therapy may reduce protein in urine and the progression of kidney disease.
View the symptoms of Alport syndrome
Diseases related to Alport syndrome
References
Kashtan CE. Alport Syndrome: Achieving Early Diagnosis and Treatment. Am J Kidney Dis. 2021 Feb;77(2):272-279. doi: 10.1053/j.ajkd.2020.03.026. Epub 2020 Jul 22. PMID: 32712016.
https://www.ajkd.org/article/S0272-6386(20)30734-4/fulltext
Nozu K, Nakanishi K, Abe Y, Udagawa T, Okada S, Okamoto T, Kaito H, Kanemoto K, Kobayashi A, Tanaka E, Tanaka K, Hama T, Fujimaru R, Miwa S, Yamamura T, Yamamura N, Horinouchi T, Minamikawa S, Nagata M, Iijima K. A review of clinical characteristics and genetic backgrounds in Alport syndrome. Clin Exp Nephrol. 2019 Feb;23(2):158-168. doi: 10.1007/s10157-018-1629-4. Epub 2018 Aug 20. PMID: 30128941; PMCID: PMC6510800.
https://link.springer.com/article/10.1007/s10157-018-1629-4
Savige J, Ariani F, Mari F, Bruttini M, Renieri A, Gross O, Deltas C, Flinter F, Ding J, Gale DP, Nagel M, Yau M, Shagam L, Torra R, Ars E, Hoefele J, Garosi G, Storey H. Expert consensus guidelines for the genetic diagnosis of Alport syndrome. Pediatr Nephrol. 2019 Jul;34(7):1175-1189. doi: 10.1007/s00467-018-3985-4. Epub 2018 Jul 9. PMID: 29987460.
https://link.springer.com/article/10.1007/s00467-018-3985-4
Torra R, Furlano M. New therapeutic options for Alport syndrome. Nephrol Dial Transplant. 2019 Aug 1;34(8):1272-1279. doi: 10.1093/ndt/gfz131. PMID: 31190059.
https://academic.oup.com/ndt/article/34/8/1272/5514265
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan