Hereditary Nephritis (Alport Syndrome) Quiz
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Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Apr 22, 2024
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Blood in urine
Eye problems
Blood in pee
My eyesight is deteriorating
Hematuria
My eyesight is getting worse
Urine is red-brown
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With an easy 3-min questionnaire , Ubie's AI-powered system will generate a free report on possible causes.
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Age - adjusts our guidance based on any age-related health factors.
History - considers past illnesses, surgeries, family history, and lifestyle choices.
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Gross hematuria
- Abdominal pain
- Ear problems
- Cloudy urine
- Frequent urination
- Hearing loss worse on the right
- Lower abdominal pain
- Foamy urine
- Blood clots in urine
- Hearing issues
- Burning sensation when urinating
- Bleeding from the urethra
- Hard of hearing in both ears but more on one side
- Red brown urine
- Pee mixed with blood
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Try Free Symptom QuizWhat is Hereditary Nephritis (Alport Syndrome)?
A rare genetic disorder characterized by progressive kidney disease and abnormalities of the inner ear and the eye. It usually presents as blood in the urine, high blood pressure and swelling (edema).
Typical Symptoms of Hereditary Nephritis (Alport Syndrome)
- Bloody or red urine
- Swelling of the arms or hands
- Kidney failure on dialysis
- Hearing difficulty
- Poor vision
- Facial swelling
- Fever
- Family history of kidney disease
Diagnostic Questions for Hereditary Nephritis (Alport Syndrome)
Your doctor may ask these questions to check for this disease:
- Have you ever had red or brown urine?
- Are your hands or arms swollen?
- Are you currently on dialysis?
- Do you have trouble hearing?
- Is your eyesight getting worse lately?
Treatment of Hereditary Nephritis (Alport Syndrome)
The treatment is directed toward the specific symptoms that are apparent in each individual. Angiotensin-converting enzyme (ACE inhibitor) therapy or angiotensin receptor blockers (ARB) therapy may reduce protein in urine and the progression of kidney disease.
Think you might have
Hereditary Nephritis (Alport Syndrome)?
Try a symptom check testSymptoms Related to Hereditary Nephritis (Alport Syndrome)
Diseases Related to Hereditary Nephritis (Alport Syndrome)
References
Kashtan CE. Alport Syndrome: Achieving Early Diagnosis and Treatment. Am J Kidney Dis. 2021 Feb;77(2):272-279. doi: 10.1053/j.ajkd.2020.03.026. Epub 2020 Jul 22. PMID: 32712016.
https://www.ajkd.org/article/S0272-6386(20)30734-4/fulltextNozu K, Nakanishi K, Abe Y, Udagawa T, Okada S, Okamoto T, Kaito H, Kanemoto K, Kobayashi A, Tanaka E, Tanaka K, Hama T, Fujimaru R, Miwa S, Yamamura T, Yamamura N, Horinouchi T, Minamikawa S, Nagata M, Iijima K. A review of clinical characteristics and genetic backgrounds in Alport syndrome. Clin Exp Nephrol. 2019 Feb;23(2):158-168. doi: 10.1007/s10157-018-1629-4. Epub 2018 Aug 20. PMID: 30128941; PMCID: PMC6510800.
https://link.springer.com/article/10.1007/s10157-018-1629-4Savige J, Ariani F, Mari F, Bruttini M, Renieri A, Gross O, Deltas C, Flinter F, Ding J, Gale DP, Nagel M, Yau M, Shagam L, Torra R, Ars E, Hoefele J, Garosi G, Storey H. Expert consensus guidelines for the genetic diagnosis of Alport syndrome. Pediatr Nephrol. 2019 Jul;34(7):1175-1189. doi: 10.1007/s00467-018-3985-4. Epub 2018 Jul 9. PMID: 29987460.
https://link.springer.com/article/10.1007/s00467-018-3985-4Torra R, Furlano M. New therapeutic options for Alport syndrome. Nephrol Dial Transplant. 2019 Aug 1;34(8):1272-1279. doi: 10.1093/ndt/gfz131. PMID: 31190059.
https://academic.oup.com/ndt/article/34/8/1272/5514265Watson S, Padala SA, Hashmi MF, et al. Alport Syndrome. [Updated 2023 Aug 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470419/
https://www.ncbi.nlm.nih.gov/books/NBK470419/#:~:text=Alport%20syndrome%20is%20a%20genetic,hematuria%2C%20edema%2C%20and%20hypertension.
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This symptom checker site is a great resource to either get an idea of what is happening inside your body or even get a second opinion without incurring another huge bill. It also provides a way to connect with a professional if needed. I really enjoy this site.
Aug 30, 2024 (Female, 40s)
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
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