Amyloidosis Quiz

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Caroline M. Doan

Caroline M. Doan, DO (Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Amyloidosis

Content updated on Sep 20, 2022

What is amyloidosis?

A disease where "amyloid", an abnormal type of protein, is deposited and builds up in various organs and damages them. The affected areas can include the heart, kidneys, and gastrointestinal tract. The causes are diverse.

Symptoms of amyloidosis

  • Constipation

  • Pain across the entire body

  • Nausea or vomiting

  • Numbness of the fingers

  • Fatigue

  • Stomach feels bloated

Questions your doctor may ask to check for amyloidosis

Your doctor may ask these questions to diagnose amyloidosis

  • Do you have hard stools or constipation recently?

  • Do you have pain all over the body?

  • Do you have nausea or vomiting?

  • Do you have numbness from your wrist down?

  • Do you feel fatigued?

Treatment for amyloidosis

There is currently no cure for amyloidosis, hence treatment focuses on slowing the disease and managing any symptoms. As organs become damaged, treatments like dialysis or organ transplants may be needed.

View the symptoms of Amyloidosis

References

  • Wechalekar AD, Gillmore JD, Hawkins PN. Systemic amyloidosis. Lancet. 2016 Jun 25;387(10038):2641-2654. doi: 10.1016/S0140-6736(15)01274-X. Epub 2015 Dec 21. PMID: 26719234.

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01274-X/fulltext

  • Falk RH, Alexander KM, Liao R, Dorbala S. AL (Light-Chain) Cardiac Amyloidosis: A Review of Diagnosis and Therapy. J Am Coll Cardiol. 2016 Sep 20;68(12):1323-41. doi: 10.1016/j.jacc.2016.06.053. PMID: 27634125.

    https://www.sciencedirect.com/science/article/pii/S0735109716346046?via%3Dihub

  • Vaxman I, Gertz M. When to Suspect a Diagnosis of Amyloidosis. Acta Haematol. 2020;143(4):304-311. doi: 10.1159/000506617. Epub 2020 Apr 27. PMID: 32340017.

    https://www.karger.com/Article/FullText/506617

  • Khoor A, Colby TV. Amyloidosis of the Lung. Arch Pathol Lab Med. 2017 Feb;141(2):247-254. doi: 10.5858/arpa.2016-0102-RA. PMID: 28134587.

    https://meridian.allenpress.com/aplm/article/141/2/247/132695/Amyloidosis-of-the-Lung

  • Ihne S, Morbach C, Sommer C, Geier A, Knop S, Störk S. Amyloidosis-the Diagnosis and Treatment of an Underdiagnosed Disease. Dtsch Arztebl Int. 2020 Mar 6;117(10):159-166. doi: 10.3238/arztebl.2020.0159. PMID: 32295695; PMCID: PMC7171477.

    https://www.aerzteblatt.de/int/archive/article/212836

Reviewed By:

Caroline M. Doan

Caroline M. Doan, DO (Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

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