Amyloidosis quiz
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Learn more about Amyloidosis
Content updated on Jun 1, 2022
What is amyloidosis?
A disease where "amyloid", a type of protein, is deposited in various organs and damages them. The affected areas include the heart, kidneys and gastrointestinal tract. The causes are diverse.
Symptoms related to amyloidosis
Facial swelling
Red or yellow skin lumps
Smooth, shiny lump on the skin
Constipation
Pain across the entire body
History of kidney failure
Swollen legs / fluid retention in the legs
Nausea or vomiting
Questions your doctor may ask to check for amyloidosis
Your doctor may ask these questions to diagnose amyloidosis
Do you have facial swelling?
Do you have yellow or red lumps/bumps on your skin?
Is there a shiny or waxy, pearl-like lump on the skin?
Do you have hard stools or constipation recently?
Do you have pain all over the body?
Treatment for amyloidosis
There is currently no cure for amyloidosis, hence treatment focuses on slowing the disease and managing any symptoms. As organs become damaged, treatments like dialysis or organ transplants may be needed.
View the symptoms of Amyloidosis
Diseases related to Amyloidosis
References
Wechalekar AD, Gillmore JD, Hawkins PN. Systemic amyloidosis. Lancet. 2016 Jun 25;387(10038):2641-2654. doi: 10.1016/S0140-6736(15)01274-X. Epub 2015 Dec 21. PMID: 26719234.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01274-X/fulltext
Falk RH, Alexander KM, Liao R, Dorbala S. AL (Light-Chain) Cardiac Amyloidosis: A Review of Diagnosis and Therapy. J Am Coll Cardiol. 2016 Sep 20;68(12):1323-41. doi: 10.1016/j.jacc.2016.06.053. PMID: 27634125.
https://www.sciencedirect.com/science/article/pii/S0735109716346046?via%3Dihub
Vaxman I, Gertz M. When to Suspect a Diagnosis of Amyloidosis. Acta Haematol. 2020;143(4):304-311. doi: 10.1159/000506617. Epub 2020 Apr 27. PMID: 32340017.
https://www.karger.com/Article/FullText/506617
Khoor A, Colby TV. Amyloidosis of the Lung. Arch Pathol Lab Med. 2017 Feb;141(2):247-254. doi: 10.5858/arpa.2016-0102-RA. PMID: 28134587.
https://meridian.allenpress.com/aplm/article/141/2/247/132695/Amyloidosis-of-the-Lung
Ihne S, Morbach C, Sommer C, Geier A, Knop S, Störk S. Amyloidosis-the Diagnosis and Treatment of an Underdiagnosed Disease. Dtsch Arztebl Int. 2020 Mar 6;117(10):159-166. doi: 10.3238/arztebl.2020.0159. PMID: 32295695; PMCID: PMC7171477.
https://www.aerzteblatt.de/int/archive/article/212836
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan