Benign Familial Pemphigus (Hailey-Hailey Disease) Quiz

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Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Family Medicine)

Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.

Yukiko Ueda, MD

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

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Content updated on Apr 4, 2024

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With an easy 3-min questionnaire , Ubie's AI-powered system will generate a free report on possible causes.

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People with similar symptoms also use Ubie's symptom checker to find possible causes

  • Bulging patch of skin

  • Healing skin lesion

  • Pus in the breast

  • Smelly bumps

  • Red rash

  • Black scabs

  • Pus in the chest

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What is Benign Familial Pemphigus (Hailey-Hailey Disease)?

This rare, inherited, lifelong condition causes blistering rashes on the skin, particularly in skin folds like armpits or genitals. It results from a gene defect in cells that help skin cells stick together. Factors that worsen the condition include sunlight, sweat, heat, and friction. It can develop at any age but typically appears in the second or third decade of life.

Typical Symptoms of Benign Familial Pemphigus (Hailey-Hailey Disease)

  • Bumps containing pus

  • Scab

  • Skin redness or red bumpy rashes

Doctor's Diagnostic Questionson Benign Familial Pemphigus (Hailey-Hailey Disease)

Your doctor may ask these questions to check for this disease:

  • Do you have pus-filled bumps on your skin?

  • Do you have a scab?

  • Do you have red skin or red spots?

Treatmentof Benign Familial Pemphigus (Hailey-Hailey Disease)

Treatment depends on an individual's specific symptoms and their severity. Mild cases may not need medical treatment. Creams, ointments, and oral medications are commonly prescribed. Avoiding triggers like sweating and friction is recommended when possible.

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Benign Familial Pemphigus (Hailey-Hailey Disease)

View the symptoms of Benign Familial Pemphigus (Hailey-Hailey Disease)

  • Pustule

  • Scab

  • Red skin

Diseases related to Benign Familial Pemphigus (Hailey-Hailey Disease)

References

  • Rogner DF, Lammer J, Zink A, Hamm H. Darier and Hailey-Hailey disease: update 2021. J Dtsch Dermatol Ges. 2021 Oct;19(10):1478-1501. doi: 10.1111/ddg.14619. PMID: 34661345.

  • Konstantinou MP, Krasagakis K. Benign Familial Pemphigus (Hailey-Hailey Disease) [Updated 2023 Aug 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK585136/

    https://www.ncbi.nlm.nih.gov/books/NBK585136/#:~:text=Hailey%2DHailey%20disease%20(HHD),%E2%80%9Crhagades%E2%80%9D%20in%20flexural%20areas

User Testimonials

Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Family Medicine)

Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.

Yukiko Ueda, MD

Yukiko Ueda, MD (Dermatology)

Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.

From our team of 50+ doctors

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