Palmoplantar Pustulosis Quiz

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Yukiko Ueda, MD (Dermatology)

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Learn more about Palmoplantar pustulosis

Content updated on Sep 20, 2022

What is palmoplantar pustulosis?

In this condition, small blisters filled with pus repeatedly appear on the palms and soles. The exact cause is unknown.

Symptoms of palmoplantar pustulosis

  • Skin abnormality

  • New bumps appearing while some bumps are healing already

  • Rash that affects my left and right side equally

  • Bumps containing pus

  • Skin Itching

  • Skin problem on the feet, beyond the ankle

  • Skin problem over the back of the hand

  • Previous allergic reaction to metals

Questions your doctor may ask to check for palmoplantar pustulosis

Your doctor may ask these questions to diagnose palmoplantar pustulosis

  • Do you have any skin problems?

  • Is there a mix of improving and new rashes?

  • Do you have similar skin symptoms on both sides of the body (symmetric)?

  • Do you have bumps on your skin with pus?

  • Do you have itchy skin?

Treatment for palmoplantar pustulosis

Treatment of this condition does not cure it, but aims to shorten and decrease flare-ups. The doctor may recommend moisturizers, creams or oral medications. In some cases, phototherapy (shining the areas with UV light) may be helpful.

View the symptoms of Palmoplantar pustulosis


  • Raposo I, Torres T. Palmoplantar Psoriasis and Palmoplantar Pustulosis: Current Treatment and Future Prospects. Am J Clin Dermatol. 2016 Aug;17(4):349-58. doi: 10.1007/s40257-016-0191-7. PMID: 27113059.

  • Murakami M, Terui T. Palmoplantar pustulosis: Current understanding of disease definition and pathomechanism. J Dermatol Sci. 2020 Apr;98(1):13-19. doi: 10.1016/j.jdermsci.2020.03.003. Epub 2020 Mar 14. PMID: 32201085.

  • Misiak-Galazka M, Zozula J, Rudnicka L. Palmoplantar Pustulosis: Recent Advances in Etiopathogenesis and Emerging Treatments. Am J Clin Dermatol. 2020 Jun;21(3):355-370. doi: 10.1007/s40257-020-00503-5. PMID: 32008176; PMCID: PMC7275027.

  • Yamamoto T. Similarity and difference between palmoplantar pustulosis and pustular psoriasis. J Dermatol. 2021 Jun;48(6):750-760. doi: 10.1111/1346-8138.15826. Epub 2021 Mar 2. PMID: 33650702.

  • Murakami M. Guselkumab for the treatment of palmoplantar pustulosis. Expert Opin Biol Ther. 2020 Aug;20(8):841-852. doi: 10.1080/14712598.2020.1760244. Epub 2020 May 12. PMID: 32321322.

Reviewed By:

Yukiko Ueda

Yukiko Ueda, MD (Dermatology)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

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Kameda Medical Center, Japan

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