Chronic Fatigue Syndrome Quiz
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Easily tired
Constant fatigue
Headache
Malaise
Fatigue throughout the day
Unrefreshing sleep
Muscle pain
Brain fog
Sore muscles
Insomnia
Feeling depressed for no reason
Not seeing your symptoms? No worries!
What is Chronic Fatigue Syndrome?
A condition in which fatigue and low energy levels last for an extended period (months to years). It can greatly impair patients' daily activities. The physical causes are currently not well understood.
Typical Symptoms of Chronic Fatigue Syndrome
- Stressed over daily life
- Episodes of sudden, overwhelming daytime sleepiness
- Fatigue or low energy that is worse in the morning
- Dizziness
- Difficulty concentrating
- Forehead pain
- Decreased motivation
- Persistent fatigue and lack of motivation
Diagnostic Questions for Chronic Fatigue Syndrome
Your doctor may ask these questions to check for this disease:
- Do you feel stressed or unhappy about going to work or school?
- Do you have episodes of sudden, overwhelming daytime sleepiness?
- Do you experience fatigue or low energy that is worse in the morning?
- Do you feel dizzy?
- Do you have difficulty concentrating?
Treatment of Chronic Fatigue Syndrome
There is no specific cure for this condition. Often, patients find relief with lifestyle changes such as ensuring adequate sleep, spacing out activities, and avoiding alcohol, smoking, and caffeine.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yu Shirai, MD (Psychiatry)
Dr. Shirai works at the Yotsuya Yui Clinic for mental health treatment for English and Portuguese-speaking patients. He treats a wide range of patients from neurodevelopmental disorders to dementia in children and participates in knowledge sharing through the Diversity Clinic.
Content updated on Jan 14, 2025
Following the Medical Content Editorial Policy
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This questionnaire is customized to your situation and symptoms, including the following personal information:
Biological Sex - helps us provide relevant suggestions for male vs. female conditions.
Age - adjusts our guidance based on any age-related health factors.
History - considers past illnesses, surgeries, family history, and lifestyle choices.
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Dizziness
- Can't focus
- Dizziness multiple times
- Easily distracted
- Off-balance like floating
- I can not concentrate on my work
- Spinning feeling
- Unable to sit for a long time
- A sense of motion or spinning (vertigo)
- Feeling faint
- My brain is not functioning
- Dizzy when standing up
- Less willpower to do things
- Dizzy in the morning
- Making careless mistakes
See full list
Symptoms Related to Chronic Fatigue Syndrome
Diseases Related to Chronic Fatigue Syndrome
FAQs
Q.
Creatine for Women 30-45: Solve Fatigue & Your Next Steps
A.
Creatine can help some women ages 30 to 45 feel less fatigued by boosting muscle and brain energy, improving strength and recovery, and sometimes sharpening mental clarity; creatine monohydrate is generally safe at 3 to 5 g daily for healthy adults. There are several factors to consider, since creatine is not a cure for medical fatigue and you may need to rule out causes like low iron, thyroid issues, poor sleep, or depression; see below for dosing details, side effects, who should avoid it, and the step by step plan to decide whether to start and when to see a doctor.
References:
* Mondo H, Bizzarri M, Foti F, Scoglio M, Mancuso M. Brain creatine levels and creatine supplementation: A comprehensive review. Nutrients. 2022 Aug 23;14(17):3481. doi: 10.3390/nu14173481. PMID: 36077587; PMCID: PMC9459521.
* Smith-Ryan AE, Cabre HE, Varanoske AN, Egan B, Harvey A,3, Stegen S, Campbell Z, Doyle L, Ryan ED, Stout JR, Roschel H, Gualano B, Trexler ET. Creatine Supplementation in Women: A Review of the Literature. Nutrients. 2021 Mar 8;13(3):877. doi: 10.3390/nu13030877. PMID: 33800627; PMCID: PMC8004513.
* Brosnan ME, da Silva RP, Brosnan JT. Creatine and its implications for women. Amino Acids. 2018 Jul;50(7):869-877. doi: 10.1007/s00726-018-2561-1. Epub 2018 Apr 18. PMID: 29670942; PMCID: PMC6019060.
* Wang X, Liu C, Ren F, Ren X, Liu Y, Li G, Li C, Wang Y. Creatine supplementation and muscle strength in older adults: A meta-analysis of randomized controlled trials. Exp Gerontol. 2022 May;161:111771. doi: 10.1016/j.exger.2022.111771. Epub 2022 Mar 15. PMID: 35306354.
* Kandilarov E, Sabotinov K, Nikolov M, Velikova S. Creatine for the Treatment of Depression: A Systematic Review and Meta-Analysis. J Affect Disord. 2020 Feb 1;262:239-247. doi: 10.1016/j.jad.2019.09.088. Epub 2019 Oct 14. PMID: 31756534.
Q.
Ginger for Women 30-45: Relieve Chronic Symptoms & Your Next Steps
A.
Ginger can help women 30 to 45 relieve ongoing bloating and nausea, menstrual cramps, low-grade inflammation, headaches, and related fatigue when used consistently in tea, fresh root, or capsule form. There are several factors to consider; see below for evidence-backed amounts, how it works, and ways to combine it with simple habits for better results. It is supportive, not a cure, and certain people should use caution such as those on blood thinners, pregnant or with gallbladder issues, and anyone with severe or worsening symptoms should speak with a doctor, so review the details below to guide your safest next steps.
References:
* Mazidi M, et al. The effect of ginger (Zingiber officinale) on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. J Ethnopharmacol. 2021 May 23;272:113943. doi: 10.1016/j.jep.2021.113943. Epub 2021 Feb 18. PMID: 33609805.
* Moini Jazani A, et al. The Efficacy of Ginger in the Treatment of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Complement Ther Med. 2022 Dec;71:102874. doi: 10.1016/j.ctim.2022.102874. Epub 2022 Oct 26. PMID: 36306509.
* Chen Y, et al. Efficacy of ginger in the treatment of migraine headache: a systematic review and meta-analysis. J Headache Pain. 2021 Jun 26;22(1):71. doi: 10.1186/s10194-021-01281-2. PMID: 34172088; PMCID: PMC8234390.
* Hani M, et al. A systematic review and meta-analysis of the effect of ginger on nausea and vomiting in adults with chronic conditions. Complement Ther Med. 2023 Dec;79:102970. doi: 10.1016/j.ctim.2023.102970. Epub 2023 Nov 2. PMID: 37923481.
* Bodagh MN, et al. The Potential Role of Ginger (Zingiber officinale Roscoe) in the Management of Oxidative Stress and Inflammation: A Narrative Review. J Complement Integr Med. 2023 Apr 19;20(2):645-667. doi: 10.1515/jcim-2022-0391. PMID: 36728080.
Q.
Healthy Breakfast for Women 30-45: Fix Fatigue & Next Steps
A.
For women 30 to 45 with fatigue, a balanced breakfast can steady energy: aim for 20 to 30 g protein with fiber-rich carbs and healthy fats, eat within 1 to 2 hours of waking, and avoid coffee-only or sugary starts. Try this for 2 to 3 weeks, track mood and focus, adjust as needed, and address nutrient gaps like iron, B12, and magnesium; see a clinician if fatigue persists or you have shortness of breath, chest pain, unexplained weight loss, dizziness, or fainting. There are several factors to consider, including meal ideas, hormone and stress tips, and when to test for thyroid or anemia, all explained below.
References:
* Al-Dujaili A, Dinc A, Hiller J, Singh T, Kordowicz A, Zdzieblik D, Köhnen E, König D. Dietary patterns and fatigue in women: a systematic review. Nutrients. 2021 Jul 20;13(7):2454. doi: 10.3390/nu13072454. PMID: 34371946; PMCID: PMC8308801.
* Leidy HJ, Bossingham MJ, Mattes RD, Campbell WW. Impact of a high-protein breakfast on satiety, energy intake, and postprandial glucose regulation in healthy women. Obesity (Silver Spring). 2011 Oct;19(10):1982-9. doi: 10.1038/oby.2011.167. PMID: 21778942; PMCID: PMC3207865.
* Biesalski HK, Tinz J. Micronutrient deficiencies in women: Implications for health and well-being. Nutrients. 2018 Jul 11;10(7):858. doi: 10.3390/nu10070858. PMID: 29997328; PMCID: PMC6073752.
* Adolphs P, Kreutzmann I, Seppelt C, Nothlings U. The role of breakfast on the nutritional and health status of adults. Nutrients. 2019 Mar 16;11(3):643. doi: 10.3390/nu11030643. PMID: 30884976; PMCID: PMC6471691.
* Al-Dujaili A, Singh T, König D. Dietary Approaches to Managing Fatigue: A Narrative Review. J Nutr Sci. 2021 Mar 15;10:e18. doi: 10.1017/jns.2021.9. PMID: 33903960; PMCID: PMC8069695.
Q.
Introvert Burnout or Health Issue? A Woman’s Guide & Next Steps
A.
There are several factors to consider: for many women, introvert burnout improves with quiet recovery and consistent sleep, while fatigue that lasts weeks, unrefreshing sleep, or new physical symptoms can point to medical causes such as iron deficiency, thyroid or sleep disorders, depression or anxiety, ME/CFS, or autoimmune disease. Next steps include briefly tracking symptoms, trying targeted introvert recovery, considering a symptom check, and contacting a doctor if symptoms persist, worsen, or feel urgent like chest pain or fainting; important details that can shape your choices are outlined below.
References:
* Ahmadi S, Zohra H. Burnout and health among working women: a systematic review. J Community Psychol. 2022 Mar;50(3):1398-1420. doi: 10.1002/jcop.22822. Epub 2021 Sep 20. PMID: 34549887.
* Sorkin H, Sheppes G, Shvartzvald A, Mintz M. Burnout, well-being and personality traits: The moderating role of work-life balance satisfaction among university academic and professional staff. PLoS One. 2023 Jul 20;18(7):e0288860. doi: 10.1371/journal.pone.0288860. PMID: 37471676; PMCID: PMC10359052.
* Slater E, Alpert M, Elovitz M, Alpert SH. Chronic Stress and Health in Women: A Systematic Review. J Womens Health (Larchmt). 2024 Jan;33(1):3-16. doi: 10.1089/jwh.2023.0189. Epub 2023 Oct 17. PMID: 37843817.
* Charkos ZK, Wintner H. Gender Differences in Burnout and Associated Psychological Distress: A Systematic Review. Int J Environ Res Public Health. 2023 Jan 26;20(3):2148. doi: 10.3390/ijerph20032148. PMID: 36767272; PMCID: PMC9914717.
* Eskelinen JJ, Järvi H, Pirkola S, Törnwall-Virk J, Tikkala A, Pihlajavesi M, Suvisaari J, Väänänen JM, Poutanen O. A Systematic Review on Psychosomatic Interventions to Reduce Burnout. Int J Environ Res Public Health. 2023 May 10;20(10):5844. doi: 10.3390/ijerph20105844. PMID: 37239556; PMCID: PMC10218764.
Q.
Ketamine for Women: Healing Chronic Symptoms & Your Next Steps
A.
Ketamine can be a fast-acting option for women with treatment-resistant depression, acute suicidal thoughts, PTSD, and some chronic pain by targeting glutamate pathways, with strongest support in depression and limited evidence for chronic fatigue. There are several factors to consider. See below for who is a good candidate and who should avoid it, safety and side effects, treatment formats and schedules, female-specific considerations like hormonal timing and integration therapy, and step-by-step next moves such as clarifying your diagnosis, speaking with a qualified doctor, and choosing a reputable clinic.
References:
* Soni M, Gupta A, Bista SR. Sex Differences in the Effects of Ketamine on Pain and Mood. *Pain Rep*. 2020 Jan 23;5(1):e809. pubmed.ncbi.nlm.nih.gov/32095627/
* Koutsouleris N, O'Day D, Stone JM. Sex Differences in Depression and Antidepressant Effects: Ketamine and Beyond. *Curr Top Behav Neurosci*. 2019;42:251-274. pubmed.ncbi.nlm.nih.gov/31346746/
* Abdallah CG, Averill LA, Krystal JH. Ketamine for Posttraumatic Stress Disorder: A Systematic Review. *J Clin Psychopharmacol*. 2020 Jan/Feb;40(1):16-24. pubmed.ncbi.nlm.nih.gov/31904797/
* Niesters M, Kim YC, Dahan A. Ketamine and Its Role in the Treatment of Chronic Pain: A Review. *Pain Res Manag*. 2021 Jun 25;2021:6651913. pubmed.ncbi.nlm.nih.gov/34220556/
* Fava M, Saccà F, Rossi M, Fornaro M. Safety and Tolerability of Ketamine for Psychiatric Disorders: A Systematic Review and Meta-Analysis. *J Clin Psychiatry*. 2020 Jan 28;81(1):19r12833. pubmed.ncbi.nlm.nih.gov/32017366/
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Yancey JR, Thomas SM. Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician. 2012 Oct 15;86(8):741-6. PMID: 23062157.
https://www.aafp.org/pubs/afp/issues/2012/1015/p741.htmlTurner-Stokes L, Wade DT. Updated NICE guidance on chronic fatigue syndrome. BMJ. 2020 Dec 16;371:m4774. doi: 10.1136/bmj.m4774. PMID: 33328173.
https://www.bmj.com/content/371/bmj.m4774Bested AC, Marshall LM. Review of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: an evidence-based approach to diagnosis and management by clinicians. Rev Environ Health. 2015;30(4):223-49. doi: 10.1515/reveh-2015-0026. PMID: 26613325.
https://www.degruyter.com/document/doi/10.1515/reveh-2015-0026/html