Congenital Biliary Atresia Quiz

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Reviewed By:

Yuta Sasaoka, MD

Yuta Sasaoka, MD (Pediatrics)

Dr. Sasaoka graduated from the Sapporo Medical University School of Medicine. After working in the Department of Pediatrics at Hakodate Municipal Hospital, the Emergency Center at Hakodate Municipal Hospital, and the Department of Emergency Medicine at Tokyo Metropolitan Children's General Medical Center, he joined the Sapporo Medical University Advanced Emergency Medical Center in April 2020. Dr. Sasaoka is well versed in pediatric emergency medicine, covering a wide range of pediatrics and emergency medicine. He is also a certified AHA-PALS instructor and focuses on pediatric secondary life support education at the Hokkaido Training Site.

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Learn more about Congenital biliary atresia

Content updated on Nov 2, 2022

What is congenital biliary atresia?

A condition in which a baby is born with abnormally narrow or even absent bile ducts in the liver. It can cause rapid liver failure, so prompt medical attention is needed. The exact cause is unclear, but genetics and exposure to certain toxins may play a role.

Symptoms of congenital biliary atresia

  • Stools became cream or white colored at 1 month of age

  • Skin or eyes turning yellow

  • Intensely yellow urine

  • Nausea or vomiting

  • My brain is not functioning right now

  • Unable to gain weight

Questions your doctor may ask to check for congenital biliary atresia

Your doctor may ask these questions to diagnose congenital biliary atresia

  • Has the stool been gradually getting lighter after 1 month of age? (e.g. from pale yellow/green to grey/white)

  • Have you noticed your eyes or skin are turning yellow?

  • Is your urine dark yellow in color?

  • Do you have nausea or vomiting?

  • Do you have problems focusing or a reduced sense of awareness in your surroundings?

Treatment for congenital biliary atresia

This condition cannot be cured. Treatment options include the Kasai procedure, which reconnects bile drainage systems from the liver to the intestines. Some patients will require a liver transplant as well. Regular follow-ups with a dietitian are advised to ensure the child grows well.

View the symptoms of Congenital biliary atresia

References

  • Zhou Y, Ji H, Xu Q, Zhang X, Cao X, Chen Y, Shao M, Wu Z, Zhang J, Lu C, Yang J, Shi Y, Bu H. Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver. Theranostics. 2021 May 24;11(15):7262-7275. doi: 10.7150/thno.49116. PMID: 34158849; PMCID: PMC8210598.

    https://www.thno.org/v11p7262.htm

  • STOWENS D. CONGENITAL BILIARY ATRESIA. Ann N Y Acad Sci. 1963 Dec 30;111:337-57. doi: 10.1111/j.1749-6632.1963.tb36976.x. PMID: 14085860.

    https://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1963.tb36976.x

  • Herbst DA, Vella MA, Cannon JW. Abdominal pain in an adult with congenital biliary atresia. J Trauma Acute Care Surg. 2021 Dec 1;91(6):e166-e167. doi: 10.1097/TA.0000000000002408. PMID: 31233443.

    https://lww.com/pages/results.aspx?txtKeywords=01586154-900000000-98217

User testimonials

Reviewed By:

Yuta Sasaoka, MD

Yuta Sasaoka, MD (Pediatrics)

Dr. Sasaoka graduated from the Sapporo Medical University School of Medicine. After working in the Department of Pediatrics at Hakodate Municipal Hospital, the Emergency Center at Hakodate Municipal Hospital, and the Department of Emergency Medicine at Tokyo Metropolitan Children's General Medical Center, he joined the Sapporo Medical University Advanced Emergency Medical Center in April 2020. Dr. Sasaoka is well versed in pediatric emergency medicine, covering a wide range of pediatrics and emergency medicine. He is also a certified AHA-PALS instructor and focuses on pediatric secondary life support education at the Hokkaido Training Site.

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