Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yuta Sasaoka, MD (Pediatrics)
Dr. Sasaoka graduated from the Sapporo Medical University School of Medicine. After working in the Department of Pediatrics at Hakodate Municipal Hospital, the Emergency Center at Hakodate Municipal Hospital, and the Department of Emergency Medicine at Tokyo Metropolitan Children's General Medical Center, he joined the Sapporo Medical University Advanced Emergency Medical Center in April 2020. Dr. Sasaoka is well versed in pediatric emergency medicine, covering a wide range of pediatrics and emergency medicine. He is also a certified AHA-PALS instructor and focuses on pediatric secondary life support education at the Hokkaido Training Site.
Content updated on Mar 31, 2024
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A condition in which a baby is born with abnormally narrow or even absent bile ducts in the liver. It can cause rapid liver failure, so prompt medical attention is needed. The exact cause is unclear, but genetics and exposure to certain toxins may play a role.
Your doctor may ask these questions to check for this disease:
This condition cannot be cured. Treatment options include the Kasai procedure, which reconnects bile drainage systems from the liver to the intestines. Some patients will require a liver transplant as well. Regular follow-ups with a dietitian are advised to ensure the child grows well.
Zhou Y, Ji H, Xu Q, Zhang X, Cao X, Chen Y, Shao M, Wu Z, Zhang J, Lu C, Yang J, Shi Y, Bu H. Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver. Theranostics. 2021 May 24;11(15):7262-7275. doi: 10.7150/thno.49116. PMID: 34158849; PMCID: PMC8210598.
https://www.thno.org/v11p7262.htmSTOWENS D. CONGENITAL BILIARY ATRESIA. Ann N Y Acad Sci. 1963 Dec 30;111:337-57. doi: 10.1111/j.1749-6632.1963.tb36976.x. PMID: 14085860.
https://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.1963.tb36976.xBiliary Atresia - Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/biliary-atresia#:~:text=Biliary%20atresia%20is%20a%20blockage,system%20fails%20to%20develop%20normallyMale, 30s
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Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yuta Sasaoka, MD (Pediatrics)
Dr. Sasaoka graduated from the Sapporo Medical University School of Medicine. After working in the Department of Pediatrics at Hakodate Municipal Hospital, the Emergency Center at Hakodate Municipal Hospital, and the Department of Emergency Medicine at Tokyo Metropolitan Children's General Medical Center, he joined the Sapporo Medical University Advanced Emergency Medical Center in April 2020. Dr. Sasaoka is well versed in pediatric emergency medicine, covering a wide range of pediatrics and emergency medicine. He is also a certified AHA-PALS instructor and focuses on pediatric secondary life support education at the Hokkaido Training Site.
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