Erythema Multiforme Quiz
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Redness of the skin
Bumpy rash spread quickly to the rest of the body
Red spots on skin
The eczema spread quickly to the whole body
Skin is red
Rapidly spreading eczema like rash over the whole body
My feet are red
Not seeing your symptoms? No worries!
What is Erythema Multiforme?
Erythema multiforme is a condition that affects the skin and/or mucous membranes, usually caused by an excessive immune reaction triggered by an infection (often herpes simplex virus) or certain medications. It typically involves red, raised lesions that resemble a target or "bullseye" and may also include blisters. It can affect anyone but is more common in men and adults between ages 20-40 years.
Typical Symptoms of Erythema Multiforme
- Bumpy rash that appeared, then rapidly spread to the rest of the body
- Blisters on the skin
- Rough patches in the mouth or genitals
- Skin problems
- Redness, bumps, or irritation on the skin
- A lump or bump in the mouth
Diagnostic Questions for Erythema Multiforme
Your doctor may ask these questions to check for this disease:
- Did a small skin bump spread all over your body?
- Do you have any blisters on your skin?
- Do you have any rough patches in your mouth or genital area?
- Do you have any skin problems
- Have you noticed any redness, bumps, or irritation on your skin?
Treatment of Erythema Multiforme
Most cases are mild and don't require further treatment. Medications to reduce inflammation and relieve symptoms are prescribed. In some serious cases, hospital admission may be necessary.
Reviewed By:
Caroline M. Doan, DO (Internal Medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Trayes KP, Love G, Studdiford JS. Erythema Multiforme: Recognition and Management. Am Fam Physician. 2019 Jul 15;100(2):82-88. PMID: 31305041.
https://www.aafp.org/pubs/afp/issues/2019/0715/p82.htmlBennardo L, Nisticò SP, Dastoli S, Provenzano E, Napolitano M, Silvestri M, Passante M, Patruno C. Erythema Multiforme and COVID-19: What Do We Know? Medicina (Kaunas). 2021 Aug 16;57(8):828. doi: 10.3390/medicina57080828. PMID: 34441034; PMCID: PMC8401222.
https://www.mdpi.com/1648-9144/57/8/828Samim F, Auluck A, Zed C, Williams PM. Erythema multiforme: a review of epidemiology, pathogenesis, clinical features, and treatment. Dent Clin North Am. 2013 Oct;57(4):583-96. doi: 10.1016/j.cden.2013.07.001. PMID: 24034067.
https://www.sciencedirect.com/science/article/abs/pii/S0011853213000529?via%3DihubGrünwald P, Mockenhaupt M, Panzer R, Emmert S. Erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis - diagnosis and treatment. J Dtsch Dermatol Ges. 2020 Jun;18(6):547-553. doi: 10.1111/ddg.14118. Epub 2020 May 29. PMID: 32469468.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.14118