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Learn more about Erythema Multiforme
Content updated on 2022-06-02
What is erythema multiforme?
Erythema Multiforme is a skin condition that usually occurs as an excessive immune reaction after an infection (usually Herpes Simplex Virus) or due to certain medications. Most characteristically, it involves red, raised "target" patches, blisters on the skin. It can affect anyone, but most common between ages 20-40 years and in men.
Symptoms related to erythema multiforme
Bumpy rash that appeared, then rapidly spread to the rest of the body
Skin redness or red bumpy rashes
Questions your doctor may ask to check for erythema multiforme
Your doctor may ask these questions to diagnose erythema multiforme
Did a small lump or bump on your skin suddenly spread all over your body?
Do you have red skin or red spots on the skin?
Treatment for erythema multiforme
Most cases are mild and require no further treatment. Medications to suppress inflammation and relieve symptoms are prescribed. Occasionally, serious cases require hospital admission.
Diseases related to Erythema Multiforme
References
Trayes KP, Love G, Studdiford JS. Erythema Multiforme: Recognition and Management. Am Fam Physician. 2019 Jul 15;100(2):82-88. PMID: 31305041.
https://www.aafp.org/pubs/afp/issues/2019/0715/p82.html
Bennardo L, Nisticò SP, Dastoli S, Provenzano E, Napolitano M, Silvestri M, Passante M, Patruno C. Erythema Multiforme and COVID-19: What Do We Know? Medicina (Kaunas). 2021 Aug 16;57(8):828. doi: 10.3390/medicina57080828. PMID: 34441034; PMCID: PMC8401222.
https://www.mdpi.com/1648-9144/57/8/828
Samim F, Auluck A, Zed C, Williams PM. Erythema multiforme: a review of epidemiology, pathogenesis, clinical features, and treatment. Dent Clin North Am. 2013 Oct;57(4):583-96. doi: 10.1016/j.cden.2013.07.001. PMID: 24034067.
https://www.sciencedirect.com/science/article/abs/pii/S0011853213000529?via%3Dihub
Grünwald P, Mockenhaupt M, Panzer R, Emmert S. Erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis - diagnosis and treatment. J Dtsch Dermatol Ges. 2020 Jun;18(6):547-553. doi: 10.1111/ddg.14118. Epub 2020 May 29. PMID: 32469468.
https://onlinelibrary.wiley.com/doi/10.1111/ddg.14118
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan