Immune thrombocytopenic purpura quiz

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Yoshinori Abe

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Yoshinori Abe, MD

Internal medicine

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Learn more about Immune thrombocytopenic purpura

Content updated on Jun 1, 2022

What is immune thrombocytopenic purpura?

Immune thrombocytopenic purpura (ITP) is characterized by a decrease in platelets in the blood which are cells in the blood that help in clotting. ITP can cause easy bruising and bleeding. It occurs when the immune system mistakenly attacks and destroys platelets. Triggers include infections like HIV, hepatitis, etc.

Symptoms related to immune thrombocytopenic purpura

  • Bruising easily

  • Bloody or red urine

  • Nose or gum bleeding

  • Red spots on the skin

  • Purple rash

  • Bleeding inside joint

Questions your doctor may ask to check for immune thrombocytopenic purpura

Your doctor may ask these questions to diagnose immune thrombocytopenic purpura

  • Do you bleed easily, even due to minor injuries?

  • Is there blood in your stool?

  • Have you ever had red or brown urine (hematuria)?

  • Do you have bleeding in your nose or gums?

  • Do you have small red dots which look like bleeding under the skin?

Treatment for immune thrombocytopenic purpura

Children with ITP usually recover without treatment. Adults need treatment with medication to suppress the immune cells, increase platelet production/ prevent bleeding and blood transfusion. Rarely the spleen may need to be removed. In ITP, the immune system treats platelets as foreign and destroys them. Spleen removes these damaged platelets, hence spleen removal helps keep more platelets circulating in the body.

View the symptoms of Immune thrombocytopenic purpura

Diseases related to Immune thrombocytopenic purpura

References

  • Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002 Mar 28;346(13):995-1008. doi: 10.1056/NEJMra010501. PMID: 11919310.

    https://www.nejm.org/doi/full/10.1056/NEJMra010501

  • David P, Dotan A, Mahroum N, Shoenfeld Y. Immune Thrombocytopenic Purpura (ITP) Triggered by COVID-19 Infection and Vaccination. Isr Med Assoc J. 2021 Jun;23(6):378-380. PMID: 34155853.

    https://www.ima.org.il/MedicineIMAJ/viewarticle.aspx?year=2021&month=06&page=378

  • Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, Bussel JB, Cines DB, Chong BH, Cooper N, Godeau B, Lechner K, Mazzucconi MG, McMillan R, Sanz MA, Imbach P, Blanchette V, Kühne T, Ruggeri M, George JN. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009 Mar 12;113(11):2386-93. doi: 10.1182/blood-2008-07-162503. Epub 2008 Nov 12. PMID: 19005182.

    https://ashpublications.org/blood/article/113/11/2386/109971/Standardization-of-terminology-definitions-and

  • Candelli M, Rossi E, Valletta F, De Stefano V, Franceschi F. Immune thrombocytopenic purpura after SARS-CoV-2 vaccine. Br J Haematol. 2021 Aug;194(3):547-549. doi: 10.1111/bjh.17508. Epub 2021 May 2. PMID: 33934330; PMCID: PMC8239819.

    https://onlinelibrary.wiley.com/doi/10.1111/bjh.17508

Yoshinori Abe

Medically Reviewed By:

Yoshinori Abe, MD

Internal medicine

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