Immune Thrombocytopenic Purpura Quiz

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Respiratory medicine, Critical Care, Internal medicine

Yoshinori Abe

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Internal medicine

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Learn more about Immune thrombocytopenic purpura

Content updated on Sep 20, 2022

What is immune thrombocytopenic purpura?

Immune thrombocytopenic purpura (ITP) occurs when the immune system mistakenly attacks and destroys platelets, the cells in the blood that help to clot. ITP can cause platelet levels to drop and results in easy bruising and bleeding. Triggers include infections like HIV, hepatitis, etc.

Symptoms of immune thrombocytopenic purpura

  • Bruising easily

  • Blood in stool

  • Bloody or red urine

  • Red spots on the skin

  • Purple rash

  • Bleeding inside joint

Questions your doctor may ask to check for immune thrombocytopenic purpura

Your doctor may ask these questions to diagnose immune thrombocytopenic purpura

  • Do you bleed easily, even due to minor injuries?

  • Is there blood in your stool?

  • Have you ever had red or brown urine (hematuria)?

  • Do you have small red dots which look like bleeding under the skin?

  • Do you have purple spots on your skin?

Treatment for immune thrombocytopenic purpura

Children with ITP usually recover without treatment. Adults need treatment with medication to suppress the immune system. Blood transfusions may be required to support the body. Rarely the spleen may need to be removed to prevent the destruction of the platelets.

View the symptoms of Immune thrombocytopenic purpura

Diseases related to Immune thrombocytopenic purpura

References

  • Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002 Mar 28;346(13):995-1008. doi: 10.1056/NEJMra010501. PMID: 11919310.

    https://www.nejm.org/doi/full/10.1056/NEJMra010501

  • David P, Dotan A, Mahroum N, Shoenfeld Y. Immune Thrombocytopenic Purpura (ITP) Triggered by COVID-19 Infection and Vaccination. Isr Med Assoc J. 2021 Jun;23(6):378-380. PMID: 34155853.

    https://www.ima.org.il/MedicineIMAJ/viewarticle.aspx?year=2021&month=06&page=378

  • Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, Bussel JB, Cines DB, Chong BH, Cooper N, Godeau B, Lechner K, Mazzucconi MG, McMillan R, Sanz MA, Imbach P, Blanchette V, Kühne T, Ruggeri M, George JN. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009 Mar 12;113(11):2386-93. doi: 10.1182/blood-2008-07-162503. Epub 2008 Nov 12. PMID: 19005182.

    https://ashpublications.org/blood/article/113/11/2386/109971/Standardization-of-terminology-definitions-and

  • Candelli M, Rossi E, Valletta F, De Stefano V, Franceschi F. Immune thrombocytopenic purpura after SARS-CoV-2 vaccine. Br J Haematol. 2021 Aug;194(3):547-549. doi: 10.1111/bjh.17508. Epub 2021 May 2. PMID: 33934330; PMCID: PMC8239819.

    https://onlinelibrary.wiley.com/doi/10.1111/bjh.17508

Medically Reviewed By:

Saqib Baig

Saqib Baig, MD, MS

Respiratory medicine, Critical Care, Internal medicine

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

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