Immunodeficiency Syndrome Quiz
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Reviewed By:
Caroline M. Doan, DO (Internal medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Yoshinori Abe, MD (Internal medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
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People with these symptoms also use Ubie's symptom checker to find possible causes
Fever then no fever then fever again
Muscle pain
Periodic fever (>100.4°F / 38°C)
Have a headache
Remittent fever of 102.2°F / 39°C
Stomach was uncomfortable, then had a fever
Leg muscle pain
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Learn more about Immunodeficiency syndrome
Content updated on Sep 20, 2022
What is immunodeficiency syndrome?
This is a group of disorders affecting the immune system, reducing the body's ability to defend itself from infections and other diseases. A person can be born with such a condition (congenital) or acquire it (acquired). The severity and impact on the immune system can vary widely depending on the cause. Congenital conditions are usually due to inherited gene mutations, while acquired conditions can be caused by drugs, infections, long-term conditions and treatments, or other environmental factors.
Symptoms of immunodeficiency syndrome
Fever
Repeated episodes of fever above 100.4°F / 38°C
Muscle pain
Headache
Fever of at least 100.4°F / 38°C that continues for 7 or more days
Fatigue
Cough
Questions your doctor may ask to check for immunodeficiency syndrome
Your doctor may ask these questions to diagnose immunodeficiency syndrome
Do you have a fever?
Have you had repeated fevers of 100.4°F / 38°C or higher?
Do you have any muscle pain?
Do you have headaches or does your head feel heavy?
Are you having continuous fever of 100.4°F / 38°C or higher over more than last 7 days?
Treatment for immunodeficiency syndrome
Treatment varies depending on the cause and involves preventing infection where possible, treating infections quickly, supplementing or strengthening the immune system, and treating the underlying cause if possible. In certain cases, a bone marrow transplant may be performed to restore the body's ability to produce healthy immune cells.
View the symptoms of Immunodeficiency syndrome
Diseases related to Immunodeficiency syndrome
References
Chen LF, Yang CD, Cheng XB. Anti-Interferon Autoantibodies in Adult-Onset Immunodeficiency Syndrome and Severe COVID-19 Infection. Front Immunol. 2021 Dec 22;12:788368. doi: 10.3389/fimmu.2021.788368. PMID: 35003106; PMCID: PMC8727472.
https://www.frontiersin.org/articles/10.3389/fimmu.2021.788368/full
Zhang Q, Jing H, Su HC. Recent Advances in DOCK8 Immunodeficiency Syndrome. J Clin Immunol. 2016 Jul;36(5):441-9. doi: 10.1007/s10875-016-0296-z. Epub 2016 May 20. PMID: 27207373; PMCID: PMC4914394.
https://link.springer.com/article/10.1007/s10875-016-0296-z
User testimonials
Reviewed By:
Caroline M. Doan, DO (Internal medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Yoshinori Abe, MD (Internal medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan