Immunodeficiency Syndrome Quiz

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Caroline M. Doan

Caroline M. Doan, DO (Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Immunodeficiency syndrome

Content updated on Sep 20, 2022

What is immunodeficiency syndrome?

This is a group of disorders that affect the immune system and reduce the body's ability to defend itself from infections and other diseases. A person can be born with such a condition (congenital) or acquire it (acquired). The severity of the condition, as well as how it affects the immune system, can vary widely depending on the cause. Congenital conditions are usually due to inherited gene mutations, while acquired conditions can be caused by drugs, infections, some long-term conditions and treatments, or other environmental factors.

Symptoms of immunodeficiency syndrome

  • Lumps under the skin

  • Fever

Questions your doctor may ask to check for immunodeficiency syndrome

Your doctor may ask these questions to diagnose immunodeficiency syndrome

  • Do you feel a lump/lumps under your skin?

  • Do you have a fever?

Treatment for immunodeficiency syndrome

Treatment can vary depending on the cause. Treatment involves preventing infection where possible, treating infections quickly, supplementing or strengthening the immune system, and treating the underlying cause if possible. In certain cases, a bone marrow transplant may be performed to restore the body's ability to produce healthy immune cells.

View the symptoms of Immunodeficiency syndrome


  • Chen LF, Yang CD, Cheng XB. Anti-Interferon Autoantibodies in Adult-Onset Immunodeficiency Syndrome and Severe COVID-19 Infection. Front Immunol. 2021 Dec 22;12:788368. doi: 10.3389/fimmu.2021.788368. PMID: 35003106; PMCID: PMC8727472.

  • Zhang Q, Jing H, Su HC. Recent Advances in DOCK8 Immunodeficiency Syndrome. J Clin Immunol. 2016 Jul;36(5):441-9. doi: 10.1007/s10875-016-0296-z. Epub 2016 May 20. PMID: 27207373; PMCID: PMC4914394.

Reviewed By:

Caroline M. Doan

Caroline M. Doan, DO (Internal medicine)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Sanshiro Kato

Sanshiro Kato, MD

Emergency department

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Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

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Rohini R, MD

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