Lymphangioleiomyomatosis Quiz
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Have chest pain
Phlegm
Cough
Shortness of breath
Chest pain when I breathe
Chest pain all over
Chest pain on left side
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What is Lymphangioleiomyomatosis?
Lymphangioleiomyomatosis (LAM) results from abnormal growth of muscle cells, particularly in the lungs and lymph system. This can lead to the formation of holes or cysts in the lung and blockage or rupture of lymph vessels, causing lymph and fatty acid accumulation in the chest cavity. It is caused by gene mutations that produce proteins which cannot regulate cell growth and movement in the body.
Typical Symptoms of Lymphangioleiomyomatosis
- Chest pain when coughing or during deep breathing
- Wheezing or whistling sounds when breathing
- Pain across my entire chest
- Difficulty breathing
- Chest pain
- Left-sided chest pain
- Cough
- Right sided chest pain
Diagnostic Questions for Lymphangioleiomyomatosis
Your doctor may ask these questions to check for this disease:
- Do you have sharp chest pain when coughing or taking a deep breath?
- Do you experience wheezing or whistling sounds when breathing?
- Do you have pain over your entire chest?
- Are you experiencing difficulty breathing?
- Are you experiencing chest pain?
Treatment of Lymphangioleiomyomatosis
There is no cure for lymphangioleiomyomatosis, but treatment can help alleviate symptoms, prevent complications, and slow disease progression.
Reviewed By:
Phillip Aguila, MD, MBA (Pulmonology, Critical Care)
Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.
Eisaku Kamakura, MD (Pulmonology)
Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Whistling when I breathe
- Respiratory wheeze
- Loud breathing
- Shortness of breath when lying down
- Stridor
- Breathing out is easy but breathing in is difficult
- Right side chest pain
- Wake up in the middle of the night with shortness of breath
- Feeling that I am suffocating and will die from the breathlessness
- Shortness of breath in the morning
- Tight feeling in the chest
- Short of breath because of rapid breathing
- Shallow breathing
- Chest pain caused by exercise
- Breathing in is easy and breathing out is difficult
See full list
Symptoms Related to Lymphangioleiomyomatosis
Diseases Related to Lymphangioleiomyomatosis
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Xu KF, Xu W, Liu S, Yu J, Tian X, Yang Y, Wang ST, Zhang W, Feng R, Zhang T. Lymphangioleiomyomatosis. Semin Respir Crit Care Med. 2020 Apr;41(2):256-268. doi: 10.1055/s-0040-1702195. Epub 2020 Apr 12. PMID: 32279296.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1702195Sclafani A, VanderLaan P. Lymphangioleiomyomatosis. N Engl J Med. 2018 Jun 7;378(23):2224. doi: 10.1056/NEJMicm1712581. PMID: 29874537.
https://www.nejm.org/doi/10.1056/NEJMicm1712581McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX. Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management. Lancet Respir Med. 2021 Nov;9(11):1313-1327. doi: 10.1016/S2213-2600(21)00228-9. Epub 2021 Aug 27. PMID: 34461049.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00228-9/fulltextDoubková M, Štefániková M, Čan V, Merta Z, Svoboda M. Lymphangioleiomyomatosis. Klin Onkol. 2019 Fall;32(5):367-374. English. doi: 10.14735/amko2019367. PMID: 31610670.
https://www.linkos.cz/english-summary/klinicka-onkologie-journal/2019-10-15-5-en/lymfangioleiomyomatoza-1/