Lymphangioleiomyomatosis Quiz
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Medically Reviewed By:
Phillip Aguila, MD, MBA
Respiratory medicine, Critical Care
Eisaku Kamakura, MD
Respiratory medicine
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Learn more about Lymphangioleiomyomatosis
Content updated on Jun 1, 2022
What is lymphangioleiomyomatosis?
Lymphangioleiomyomatosis (LAM) is a result of abnormal growth of muscle cells, especially in the lungs and lymph system. It can lead to the formation of holes or cysts in the lung and block or rupture of lymph vessels causing lymph and fatty acid accumulation in the chest cavity. It's caused by gene mutations that make proteins which cannot regulate cell growth and movement in the body.
Symptoms of lymphangioleiomyomatosis
Chest pain
Cough
Phlegm
Chest pain when coughing or during deep breathing
Feeling breathless
Pain across my entire chest
Left-sided chest pain
Right sided chest pain
Questions your doctor may ask to check for lymphangioleiomyomatosis
Your doctor may ask these questions to diagnose lymphangioleiomyomatosis
Do you have any chest pain?
Do you have a cough?
Do you have phlegm?
Do you have a sharp chest pain when you cough or take a deep breath?
Are you breathless or having hard time breathing?
Treatment for lymphangioleiomyomatosis
There is no cure for lymphangioleiomyomatosis, but treatment can help ease symptoms, prevent complications and slow disease progression.
View the symptoms of Lymphangioleiomyomatosis
Diseases related to Lymphangioleiomyomatosis
References
Xu KF, Xu W, Liu S, Yu J, Tian X, Yang Y, Wang ST, Zhang W, Feng R, Zhang T. Lymphangioleiomyomatosis. Semin Respir Crit Care Med. 2020 Apr;41(2):256-268. doi: 10.1055/s-0040-1702195. Epub 2020 Apr 12. PMID: 32279296.
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1702195
Sclafani A, VanderLaan P. Lymphangioleiomyomatosis. N Engl J Med. 2018 Jun 7;378(23):2224. doi: 10.1056/NEJMicm1712581. PMID: 29874537.
https://www.nejm.org/doi/10.1056/NEJMicm1712581
McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX. Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management. Lancet Respir Med. 2021 Nov;9(11):1313-1327. doi: 10.1016/S2213-2600(21)00228-9. Epub 2021 Aug 27. PMID: 34461049.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00228-9/fulltext
Doubková M, Štefániková M, Čan V, Merta Z, Svoboda M. Lymphangioleiomyomatosis. Klin Onkol. 2019 Fall;32(5):367-374. English. doi: 10.14735/amko2019367. PMID: 31610670.
https://www.linkos.cz/english-summary/klinicka-onkologie-journal/2019-10-15-5-en/lymfangioleiomyomatoza-1/
Medically Reviewed By:
Phillip Aguila, MD, MBA
Respiratory medicine, Critical Care
Eisaku Kamakura, MD
Respiratory medicine
Just 3 minutes.
Developed by doctors.
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan