Lymphangioleiomyomatosis Quiz

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Reviewed By:

Phillip Aguila, MD, MBA

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.

Eisaku Kamakura, MD

Eisaku Kamakura, MD (Respiratory medicine)

Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.

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With an easy 3-min questionnaire, Ubie's AI-powered system will generate a free report on possible causes.

  • Trained and reviewed by 50+ doctors, our AI Symptom Checker utilizes data from 1,500+ medical centers

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  • Lymphangioleiomyomatosis as well as similar diseases can be checked at the same time.

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People with similar symptoms also use Ubie's symptom checker to find possible causes

  • Noisy breathing

  • Whistling when I breathe

  • Respiratory wheeze

  • Shortness of breath when lying down

  • Loud breathing

  • Stridor

  • Breathing out is easy but breathing in is difficult

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Learn more about Lymphangioleiomyomatosis

Content updated on Sep 20, 2022

What is lymphangioleiomyomatosis?

Lymphangioleiomyomatosis (LAM) results from abnormal growth of muscle cells, particularly in the lungs and lymph system. This can lead to the formation of holes or cysts in the lung and blockage or rupture of lymph vessels, causing lymph and fatty acid accumulation in the chest cavity. It is caused by gene mutations that produce proteins which cannot regulate cell growth and movement in the body.

Symptoms of lymphangioleiomyomatosis

  • Chest pain when coughing or during deep breathing

  • Noisy breathing; e.g. wheezing, rattling

  • Pain across my entire chest

  • Feeling breathless

  • Chest pain

  • Left-sided chest pain

  • Cough

  • Right sided chest pain

Questions your doctor may ask to check for lymphangioleiomyomatosis

  • Do you have sharp chest pain when coughing or taking a deep breath?

  • Is your breathing noisy, like wheezing or rattling?

  • Do you have pain over your entire chest?

  • Are you having difficulty breathing?

  • Do you have chest pain?

Treatment for lymphangioleiomyomatosis

There is no cure for lymphangioleiomyomatosis, but treatment can help alleviate symptoms, prevent complications, and slow disease progression.

View the symptoms of Lymphangioleiomyomatosis

References

  • Xu KF, Xu W, Liu S, Yu J, Tian X, Yang Y, Wang ST, Zhang W, Feng R, Zhang T. Lymphangioleiomyomatosis. Semin Respir Crit Care Med. 2020 Apr;41(2):256-268. doi: 10.1055/s-0040-1702195. Epub 2020 Apr 12. PMID: 32279296.

    https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1702195

  • Sclafani A, VanderLaan P. Lymphangioleiomyomatosis. N Engl J Med. 2018 Jun 7;378(23):2224. doi: 10.1056/NEJMicm1712581. PMID: 29874537.

    https://www.nejm.org/doi/10.1056/NEJMicm1712581

  • McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX. Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management. Lancet Respir Med. 2021 Nov;9(11):1313-1327. doi: 10.1016/S2213-2600(21)00228-9. Epub 2021 Aug 27. PMID: 34461049.

    https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00228-9/fulltext

  • Doubková M, Štefániková M, Čan V, Merta Z, Svoboda M. Lymphangioleiomyomatosis. Klin Onkol. 2019 Fall;32(5):367-374. English. doi: 10.14735/amko2019367. PMID: 31610670.

    https://www.linkos.cz/english-summary/klinicka-onkologie-journal/2019-10-15-5-en/lymfangioleiomyomatoza-1/

User testimonials

Reviewed By:

Phillip Aguila, MD, MBA

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.

Eisaku Kamakura, MD

Eisaku Kamakura, MD (Respiratory medicine)

Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.

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