Lymphangioleiomyomatosis Quiz

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Phillip Aguila

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Eisaku Kamakura

Eisaku Kamakura, MD (Respiratory medicine)

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Learn more about Lymphangioleiomyomatosis

Content updated on Sep 20, 2022

What is lymphangioleiomyomatosis?

Lymphangioleiomyomatosis (LAM) is a result of abnormal growth of muscle cells, especially in the lungs and lymph system. It can lead to the formation of holes or cysts in the lung and block or rupture of lymph vessels causing lymph and fatty acid accumulation in the chest cavity. It's caused by gene mutations that make proteins which cannot regulate cell growth and movement in the body.

Symptoms of lymphangioleiomyomatosis

  • Chest pain

  • Cough

  • Phlegm

  • Chest pain when coughing or during deep breathing

  • Feeling breathless

  • Pain across my entire chest

  • Left-sided chest pain

  • Right sided chest pain

Questions your doctor may ask to check for lymphangioleiomyomatosis

Your doctor may ask these questions to diagnose lymphangioleiomyomatosis

  • Do you have any chest pain?

  • Do you have a cough?

  • Do you have phlegm?

  • Do you have a sharp chest pain when you cough or take a deep breath?

  • Are you breathless or having hard time breathing?

Treatment for lymphangioleiomyomatosis

There is no cure for lymphangioleiomyomatosis, but treatment can help ease symptoms, prevent complications and slow disease progression.

View the symptoms of Lymphangioleiomyomatosis


  • Xu KF, Xu W, Liu S, Yu J, Tian X, Yang Y, Wang ST, Zhang W, Feng R, Zhang T. Lymphangioleiomyomatosis. Semin Respir Crit Care Med. 2020 Apr;41(2):256-268. doi: 10.1055/s-0040-1702195. Epub 2020 Apr 12. PMID: 32279296.

  • Sclafani A, VanderLaan P. Lymphangioleiomyomatosis. N Engl J Med. 2018 Jun 7;378(23):2224. doi: 10.1056/NEJMicm1712581. PMID: 29874537.

  • McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX. Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management. Lancet Respir Med. 2021 Nov;9(11):1313-1327. doi: 10.1016/S2213-2600(21)00228-9. Epub 2021 Aug 27. PMID: 34461049.

  • Doubková M, Štefániková M, Čan V, Merta Z, Svoboda M. Lymphangioleiomyomatosis. Klin Onkol. 2019 Fall;32(5):367-374. English. doi: 10.14735/amko2019367. PMID: 31610670.

Reviewed By:

Phillip Aguila

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Eisaku Kamakura

Eisaku Kamakura, MD (Respiratory medicine)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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