Lymphangioleiomyomatosis Quiz

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Reviewed By:

Phillip Aguila

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.

Eisaku Kamakura

Eisaku Kamakura, MD (Respiratory medicine)

Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.

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With an easy 3-min questionnaire, Ubie's AI-powered system will generate a free report on possible causes.

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  • Lymphangioleiomyomatosis as well as similar diseases can be checked at the same time.

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People with these symptoms also use Ubie's symptom checker to find possible causes

  • There is a feeling of pressure in the chest

  • Pain in the very limited area of the chest (about the size of a fingertip)

  • Chest pain with a change in temperature, when you move to a colder place

  • Decreased effort tolerance with chest pain within the last few weeks

  • Pain radiating to the ears, chin or abdomen/tummy from the neck

  • Exacerbation of chest pain symptoms within the last 3 weeks

  • Chest pain gets worse when pressing on the affected area

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Learn more about Lymphangioleiomyomatosis

Content updated on Sep 20, 2022

What is lymphangioleiomyomatosis?

Lymphangioleiomyomatosis (LAM) is a result of abnormal growth of muscle cells, especially in the lungs and lymph system. It can lead to the formation of holes or cysts in the lung and block or rupture of lymph vessels causing lymph and fatty acid accumulation in the chest cavity. It's caused by gene mutations that make proteins which cannot regulate cell growth and movement in the body.

Symptoms of lymphangioleiomyomatosis

  • Chest pain

  • Cough

  • Phlegm

  • Chest pain when coughing or during deep breathing

  • Feeling breathless

  • Pain across my entire chest

  • Left-sided chest pain

  • Right sided chest pain

Questions your doctor may ask to check for lymphangioleiomyomatosis

Your doctor may ask these questions to diagnose lymphangioleiomyomatosis

  • Do you have any chest pain?

  • Do you have a cough?

  • Do you have phlegm?

  • Do you have a sharp chest pain when you cough or take a deep breath?

  • Are you breathless or having hard time breathing?

Treatment for lymphangioleiomyomatosis

There is no cure for lymphangioleiomyomatosis, but treatment can help ease symptoms, prevent complications and slow disease progression.

View the symptoms of Lymphangioleiomyomatosis

References

  • Xu KF, Xu W, Liu S, Yu J, Tian X, Yang Y, Wang ST, Zhang W, Feng R, Zhang T. Lymphangioleiomyomatosis. Semin Respir Crit Care Med. 2020 Apr;41(2):256-268. doi: 10.1055/s-0040-1702195. Epub 2020 Apr 12. PMID: 32279296.

    https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1702195

  • Sclafani A, VanderLaan P. Lymphangioleiomyomatosis. N Engl J Med. 2018 Jun 7;378(23):2224. doi: 10.1056/NEJMicm1712581. PMID: 29874537.

    https://www.nejm.org/doi/10.1056/NEJMicm1712581

  • McCarthy C, Gupta N, Johnson SR, Yu JJ, McCormack FX. Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management. Lancet Respir Med. 2021 Nov;9(11):1313-1327. doi: 10.1016/S2213-2600(21)00228-9. Epub 2021 Aug 27. PMID: 34461049.

    https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00228-9/fulltext

  • Doubková M, Štefániková M, Čan V, Merta Z, Svoboda M. Lymphangioleiomyomatosis. Klin Onkol. 2019 Fall;32(5):367-374. English. doi: 10.14735/amko2019367. PMID: 31610670.

    https://www.linkos.cz/english-summary/klinicka-onkologie-journal/2019-10-15-5-en/lymfangioleiomyomatoza-1/

Reviewed By:

Phillip Aguila

Phillip Aguila, MD, MBA (Respiratory medicine, Critical Care)

Dr. Aguila graduated from West Virginia University School of Medicine. He has trained in Pulmonary and Critical Care Medicine at The University of North Carolina in Chapel Hill and Internal Medicine at Medical College of Pennsylvania/Hahnemann University at Allegheny General Hospital in Pittsburgh Pennsylvania. He has served as Assistant Professor since 2010.

Eisaku Kamakura

Eisaku Kamakura, MD (Respiratory medicine)

Dr. Kamakura graduated from the Tokyo Medical and Dental University, School of Dentistry, and the Niigata University School of Medicine. He trained at Yokosuka Kyosai Hospital and held positions in the Respiratory Medicine departments at Yokosuka Kyosai Hospital, Tokyo Medical and Dental University, Ome City General Hospital, and Musashino Red Cross Hospital. In 2021, he became the specially appointed assistant professor at the Department of General Medicine, Niigata University School of Medicine.

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