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Lymph swollen
Multiple lymph nodes swollen in my groin
Left leg swelling
Swelling in the neck
Have a fever
Fatigued
Periodic fever (>100.4°F / 38°C)
Not seeing your symptoms? No worries!
What is Malignant Lymphoma?
A malignant lymphoma is a cancer that starts in the body's lymphatic system cells and can spread to other body parts. There are dozens of different kinds of lymphomas which are broadly categorized as "Hodgkins Lymphomas" and "Non-Hodgkins Lymphomas" (NHL). The different types are also classified by the cell type the cancer comes from and each different type of lymphoma has its own patterns of spread, treatments, and prognosis The most frequent symptom is swollen lymph nodes. Fevers, night sweats, itchiness, and fatigue can also be seen with lymphomas as can difficulty breathing or abdominal pain. Risk factors include age, family history, a weakened immune system from medications or illness, prior cancer treatments, viral infections such as Epstein-Barr and HIV.
Typical Symptoms of Malignant Lymphoma
- Swollen lymph nodes or lumps in the neck, armpits, groin, or behind the ears
- Swelling or water retention on one side of the body
- Neck swelling
- Swelling or protrusion under ribs
- Feels a hard lump in upper right abdomen
- Whole body pain
- History of HIV or AIDS
- Recurrent fever episodes
Diagnostic Questions for Malignant Lymphoma
Your doctor may ask these questions to check for this disease:
- Do you have any swollen lymph nodes or lumps in your neck, armpits, groin, or behind your ears?
- Is one side of your body swollen?
- Is your neck swollen?
- Do you feel swelling or protrusion under your ribs?
- Do you feel a hard lump in your upper right abdomen?
Treatment of Malignant Lymphoma
Treatment depends primarily on the lymphoma type and degree of spread, as well as the patient's overall condition. Treatment is almost always "systemic" -- to the entire body -- and may include a combination of chemotherapy, immunotherapy, targeted therapy, and medication to ease symptoms as well as radiotherapy. Treatment rarely includes surgery. Transplants using stem cells or bone marrow cells are sometimes performed.
Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Swollen lymph nodes above collar bone
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- It moves when I touch the lump
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- Swelling in right abdomen below ribs
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See full list
Symptoms Related to Malignant Lymphoma
Diseases Related to Malignant Lymphoma
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Which is the best Symptom Checker?
Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Hoshino Y, Yamada I, Shimano SI. Malignant Lymphoma Mimicking Retroperitoneal Fibrosis. Intern Med. 2021 Oct 15;60(20):3345-3346. doi: 10.2169/internalmedicine.7142-21. Epub 2021 Apr 19. PMID: 33867392; PMCID: PMC8580768.
https://www.jstage.jst.go.jp/article/internalmedicine/60/20/60_7142-21/_articleAisenberg AC. Malignant lymphoma. 2. N Engl J Med. 1973 May 3;288(18):935-41. doi: 10.1056/NEJM197305032881804. PMID: 4571349.
https://www.nejm.org/doi/full/10.1056/NEJM197305032881804Aisenberg AC. Malignant lymphoma. 1. N Engl J Med. 1973 Apr 26;288(17):883-90. doi: 10.1056/NEJM197304262881705. PMID: 4348229.
https://www.nejm.org/doi/full/10.1056/NEJM197304262881705Munakata W, Terauchi T, Maruyama D, Nagai H. Revised staging system for malignant lymphoma based on the Lugano classification. Jpn J Clin Oncol. 2019 Oct 1;49(10):895-900. doi: 10.1093/jjco/hyz111. PMID: 31504700.
https://academic.oup.com/jjco/article/49/10/895/5555767