Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Mar 31, 2024
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Lymph swollen
Multiple lymph nodes swollen in my groin
Left leg swelling
Swelling in the neck
Have a fever
Fatigued
Periodic fever (>100.4°F / 38°C)
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A malignant lymphoma is a cancer that starts in the body's lymphatic system cells and can spread to other body parts. There are dozens of different kinds of lymphomas which are broadly categorized as "Hodgkins Lymphomas" and "Non-Hodgkins Lymphomas" (NHL). The different types are also classified by the cell type the cancer comes from and each different type of lymphoma has its own patterns of spread, treatments, and prognosis The most frequent symptom is swollen lymph nodes. Fevers, night sweats, itchiness, and fatigue can also be seen with lymphomas as can difficulty breathing or abdominal pain. Risk factors include age, family history, a weakened immune system from medications or illness, prior cancer treatments, viral infections such as Epstein-Barr and HIV.
Your doctor may ask these questions to check for this disease:
Treatment depends primarily on the lymphoma type and degree of spread, as well as the patient's overall condition. Treatment is almost always "systemic" -- to the entire body -- and may include a combination of chemotherapy, immunotherapy, targeted therapy, and medication to ease symptoms as well as radiotherapy. Treatment rarely includes surgery. Transplants using stem cells or bone marrow cells are sometimes performed.
Hoshino Y, Yamada I, Shimano SI. Malignant Lymphoma Mimicking Retroperitoneal Fibrosis. Intern Med. 2021 Oct 15;60(20):3345-3346. doi: 10.2169/internalmedicine.7142-21. Epub 2021 Apr 19. PMID: 33867392; PMCID: PMC8580768.
https://www.jstage.jst.go.jp/article/internalmedicine/60/20/60_7142-21/_articleAisenberg AC. Malignant lymphoma. 2. N Engl J Med. 1973 May 3;288(18):935-41. doi: 10.1056/NEJM197305032881804. PMID: 4571349.
https://www.nejm.org/doi/full/10.1056/NEJM197305032881804Aisenberg AC. Malignant lymphoma. 1. N Engl J Med. 1973 Apr 26;288(17):883-90. doi: 10.1056/NEJM197304262881705. PMID: 4348229.
https://www.nejm.org/doi/full/10.1056/NEJM197304262881705Munakata W, Terauchi T, Maruyama D, Nagai H. Revised staging system for malignant lymphoma based on the Lugano classification. Jpn J Clin Oncol. 2019 Oct 1;49(10):895-900. doi: 10.1093/jjco/hyz111. PMID: 31504700.
https://academic.oup.com/jjco/article/49/10/895/5555767Male, 30s
I got more answers in one minute through your site than I did in three hours with Google.
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Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
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Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
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Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Robin Schoenthaler, MD (Oncology)
Board certified radiation oncologist with over 30 years experience treating cancer patients. Senior physician advisor for expert medical options in adult oncology. Published award-winning essayist on medical and health issues and more.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
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