Melas Syndrome Quiz
Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Had epileptic seizures
Was having a seizure for longer than usual but less than 10 minutes
Blacked out and cannot remember what happened during the seizure
I am currently having convulsions lasting less than 5 minutes
Convulsions occurred with fever of 100.4°F / 38°C or more
There was a convulsion that the whole body was jerking
Alcohol withdrawal with seizures or fits within 2 days
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Learn more about MELAS syndrome
Content updated on Nov 2, 2022
MELAS syndrome is a rare disorder that begins in childhood and mostly affects the nervous system and muscles.
Seizure
Shorter than other children of similar age
Hearing difficulty
Weakness in arms or legs
Blind spots or blind areas in vision
Your doctor may ask these questions to diagnose MELAS syndrome
Have you had a seizure?
Are (or were) you shorter than other children around your age?
Do you have hearing problems?
Do you feel any weakness in your arms or legs?
Do you have partial loss of vision?
Treatment is mainly symptomatic. Anti-convulsant drugs are used to help prevent and control seizures associated with MELAS syndrome. Cochlear implants have been used to treat sensorineural deafness.
View the symptoms of MELAS syndrome
Diseases related to MELAS syndrome
References
El-Hattab AW, Adesina AM, Jones J, Scaglia F. MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options. Mol Genet Metab. 2015 Sep-Oct;116(1-2):4-12. doi: 10.1016/j.ymgme.2015.06.004. Epub 2015 Jun 15. PMID: 26095523.
https://www.sciencedirect.com/science/article/abs/pii/S109671921530024X?via%3Dihub
Hsu YR, Yogasundaram H, Parajuli N, Valtuille L, Sergi C, Oudit GY. MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis. Heart Fail Rev. 2016 Jan;21(1):103-116. doi: 10.1007/s10741-015-9524-5. PMID: 26712328.
https://link.springer.com/article/10.1007/s10741-015-9524-5
Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
Just 3 minutes.
Developed by doctors.
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Seiji Kanazawa, MD, PHD
Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan