Melas Syndrome Quiz

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Shohei Harase

Shohei Harase, MD (Neurology)

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Learn more about MELAS syndrome

Content updated on Nov 2, 2022

What is MELAS syndrome?

MELAS syndrome is a rare disorder that begins in childhood and mostly affects the nervous system and muscles.

Symptoms of MELAS syndrome

  • Seizure

  • Shorter than other children of similar age

  • Hearing difficulty

  • Weakness in arms or legs

  • Blind spots or blind areas in vision

Questions your doctor may ask to check for MELAS syndrome

Your doctor may ask these questions to diagnose MELAS syndrome

  • Have you had a seizure?

  • Are (or were) you shorter than other children around your age?

  • Do you have hearing problems?

  • Do you feel any weakness in your arms or legs?

  • Do you have partial loss of vision?

Treatment for MELAS syndrome

Treatment is mainly symptomatic. Anti-convulsant drugs are used to help prevent and control seizures associated with MELAS syndrome. Cochlear implants have been used to treat sensorineural deafness.

View the symptoms of MELAS syndrome


  • El-Hattab AW, Adesina AM, Jones J, Scaglia F. MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options. Mol Genet Metab. 2015 Sep-Oct;116(1-2):4-12. doi: 10.1016/j.ymgme.2015.06.004. Epub 2015 Jun 15. PMID: 26095523.

  • Hsu YR, Yogasundaram H, Parajuli N, Valtuille L, Sergi C, Oudit GY. MELAS syndrome and cardiomyopathy: linking mitochondrial function to heart failure pathogenesis. Heart Fail Rev. 2016 Jan;21(1):103-116. doi: 10.1007/s10741-015-9524-5. PMID: 26712328.

Reviewed By:

Shohei Harase

Shohei Harase, MD (Neurology)

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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