Primary Biliary Cholangitis Quiz
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Rashes
Yellow eyes
Fatigued
Swelling in the area under my right ribs
Loss of appetite
Itchy
Have a fever
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What is Primary Biliary Cholangitis?
Previously called primary biliary cirrhosis. An autoimmune disease where the body's immune system attacks the bile ducts in the liver causing inflammation and damage, slowly.
Typical Symptoms of Primary Biliary Cholangitis
- History of Sjogren's syndrome
- Black, shiny stool
- Itchy skin
- Yellowish eyes or skin
- Itchy skin that gets worse at night
- Red or yellow skin lumps
- History of liver problems
- Feels a hard lump in upper right abdomen
Diagnostic Questions for Primary Biliary Cholangitis
Your doctor may ask these questions to check for this disease:
- Have you ever been diagnosed with Sjögren's syndrome?
- Have you had black, shiny stools?
- Do you have itchy skin?
- Have you noticed any yellowing of your eyes or skin?
- Does your skin get itchier at night?
Treatment of Primary Biliary Cholangitis
While there is no cure, treatment aims to manage symptoms and slow down the disease. The doctor may prescribe medication to improve liver function and reduce liver scarring and itching. In severe cases, a liver transplant may be needed.
Reviewed By:
Samantha Nazareth, MD (Gastroenterology)
Board-certified gastroenterologist. Experience managing gastrointestinal conditions (GERD, IBS, ulcerative colitis, Crohn’s, celiac disease, NASH) within healthcare organizations (three ambulatory surgical centers, single-specialty practice, multi-specialty practice and solo practice).
Aiko Yoshioka, MD (Gastroenterology)
Dr. Yoshioka graduated from the Niigata University School of Medicine. He worked as a gastroenterologist at Saiseikai Niigata Hospital and Niigata University Medical & Dental Hospital before serving as the Deputy Chief of Gastroenterology at Tsubame Rosai Hospital and Nagaoka Red Cross Hospital. Dr. Yoshioka joined Saitama Saiseikai Kawaguchi General Hospital as Chief of Gastroenterology in April 2018.
Content updated on Feb 19, 2025
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Black poop
- White of the eyes are yellow
- Abdominal pain
- The skin is itchy and has scratches
- Tarry stools
- Icterus
- Black shiny stool
- Skin itching that worsens at night
- Coal black stool
- Itch is mild
- Poop was really dark
- Poop is like coffee grounds
- Itching
- Throwing up blood
- Scratching the skin
See full list
Symptoms Related to Primary Biliary Cholangitis
Diseases Related to Primary Biliary Cholangitis
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Hirschfield GM, Dyson JK, Alexander GJM, Chapman MH, Collier J, Hübscher S, Patanwala I, Pereira SP, Thain C, Thorburn D, Tiniakos D, Walmsley M, Webster G, Jones DEJ (Year). The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines. Gut.
https://pubmed.ncbi.nlm.nih.gov/29593060/Jones DEJ, Beuers U, Bonder A, Carbone M, Culver E, Dyson J, Gish RG, Hansen BE, Hirschfield G, Jones R, Kowdley K, Kremer AE, Lindor K, Mayo M, Mells G, Neuberger J, Prince M, Swain M, Tanaka A, Thorburn D, Trauner M, Trivedi P, Weltman M, Yeoman A, Levy C (Year). Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here? Hepatology (Baltimore, Md.).
https://pubmed.ncbi.nlm.nih.gov/38506926/Tanaka A, Ma X, Takahashi A, Vierling JM (Year). Primary biliary cholangitis. Lancet (London, England).
https://pubmed.ncbi.nlm.nih.gov/39216494/