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Have a fever
Sore throat
I have a pain in my neck
Fatigued
Swelling in the neck
Swallowing difficulties
Stomach was uncomfortable, then had a fever
Not seeing your symptoms? No worries!
Inflammation of the thyroid gland which causes high levels of thyroid hormone in the body. It usually occurs after a viral infection. It presents as pain in the neck because of the swollen and inflamed thyroid gland. Can also have difficulty swallowing, hoarseness, fatigue and fever. It can also go on to cause symptoms of high thyroid hormone such as weight loss, increased bowel movements, palpitations, sweating.
Your doctor may ask these questions to check for this disease:
Management focuses on relieving pain and addressing thyroid dysfunction. Anti-inflammatory therapy may be prescribed to reduce discomfort. If symptoms of overactive thyroid develop, medications that slow heart rate and reduce tremors can help. In cases where the thyroid becomes underactive during recovery, thyroid hormone replacement may be necessary.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Hidetaka Hamasaki, MD (Endocrinology)
Dr. Hamasaki graduated from the Hiroshima University School of Medicine and the Graduate School of Medicine, Jichi Medical University. He completed his residency at the Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine Hospital and the Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine. He has served in the National Center for Global Health and Medicine Hospital and Kohnodai Hospital and joined Hamasaki Clinic in April 2017. Dr. Hamasaki specializes in diabetes and treats a wide range of internal medicine and endocrine disorders.
Content updated on Sep 2, 2025
Following the Medical Content Editorial Policy
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Always Stressed? Why Your Cortisol is High & Medical Steps to Fix It
A.
High cortisol often stems from chronic stress, poor sleep, blood sugar swings, steroid medicines, or endocrine disorders like Cushing’s, and can show up as fatigue with insomnia, abdominal weight gain, high blood pressure or sugar, mood changes, and frequent infections. There are several factors to consider; medical steps include timed blood, saliva, or 24-hour urine testing, treating root causes, improving sleep, stabilizing blood sugar, right-sized exercise, evidence-based stress therapies, weight management, and limiting alcohol and nicotine. See below for red flags, nuances about thyroid and adrenal fatigue, and detailed guidance that could change your next steps.
References:
* Jankovic M, Peric M, Pavlovic S, Maric NP, Milovanovic S, Ignjatovic S. Targeting the HPA Axis in Psychiatric Disorders: From Mechanisms to Clinical Implications. Front Psychiatry. 2021 Jul 15;12:701721. doi: 10.3389/fpsyt.2021.701721. PMID: 34322079; PMCID: PMC8319692.
* Biller BMK, Findling JW, Gadelha MR, Gagliardi R, Gillam MP, Grassi G, Jørgensen JOL, Leung TH, Vance ML. The Many Faces of Hypercortisolism: Clinical and Biochemical Features, Diagnosis, and Management. Endocr Rev. 2023 Jun 20;44(3):477-505. doi: 10.1210/endrev/bnac038. PMID: 36879815.
* Deussing JM, Chen A. Glucocorticoid Receptor Antagonists for the Treatment of Psychiatric Disorders. Expert Opin Investig Drugs. 2020 Jul;29(7):727-738. doi: 10.1080/13543784.2020.1772648. Epub 2020 May 29. PMID: 32470129.
* Wu Y, Chen M. Non-Cushing's Hypercortisolism: The Diagnosis and Management. Ann Transl Med. 2021 Jun;9(12):1070. doi: 10.21037/atm-2021-36. PMID: 34277490; PMCID: PMC8263177.
* Lau N, Maric NP, Pavlovic S, Maric NP. Pharmacological Interventions for Stress-Induced Disorders: From Molecules to Behavior. Front Neurosci. 2020 Feb 4;14:26. doi: 10.3389/fnins.2020.00026. PMID: 32063854; PMCID: PMC7008711.
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1İremli BG, Şendur SN, Ünlütürk U. Three Cases of Subacute Thyroiditis Following SARS-CoV-2 Vaccine: Postvaccination ASIA Syndrome. J Clin Endocrinol Metab. 2021 Aug 18;106(9):2600-2605. doi: 10.1210/clinem/dgab373. PMID: 34043800; PMCID: PMC8194612.
https://academic.oup.com/jcem/article/106/9/2600/6287003Stasiak M, Lewiński A. New aspects in the pathogenesis and management of subacute thyroiditis. Rev Endocr Metab Disord. 2021 Dec;22(4):1027-1039. doi: 10.1007/s11154-021-09648-y. Epub 2021 May 5. PMID: 33950404; PMCID: PMC8096888.
https://link.springer.com/article/10.1007/s11154-021-09648-yHennessey Jv. Subacute Thyroiditis. [Updated 2018 Jun 12]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279084/
https://www.ncbi.nlm.nih.gov/books/NBK279084/#:~:text=Subacute%20thyroiditis%20(SAT)%20is%20an,vocal%20cord%20paresis%20may%20occur.Subacute Thyroiditis - Penn Medicine
https://www.pennmedicine.org/for-patients-and-visitors/patient-information/conditions-treated-a-to-z/subacute-thyroiditis