Zollinger-Ellison Syndrome Quiz

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Reviewed By:

Aiko Yoshioka

Aiko Yoshioka, MD (Gastroenterology)

Dr. Yoshioka graduated from the Niigata University School of Medicine. He worked as a gastroenterologist at Saiseikai Niigata Hospital and Niigata University Medical & Dental Hospital before serving as the Deputy Chief of Gastroenterology at Tsubame Rosai Hospital and Nagaoka Red Cross Hospital. Dr. Yoshioka joined Saitama Saiseikai Kawaguchi General Hospital as Chief of Gastroenterology in April 2018.

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People with these symptoms also use Ubie's symptom checker to find possible causes

  • Constipation and diarrhea

  • Diarrhea throughout the whole day

  • Diarrhea more common in the morning before school

  • Diarrhea decreases with lactose-free milk

  • Acid reflux

  • Loose stool

  • Alternating diarrhea and constipation

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Learn more about Zollinger-Ellison syndrome

Content updated on Sep 20, 2022

What is Zollinger-Ellison syndrome?

Zollinger-Ellison Syndrome is a rare condition where one or more tumors in the stomach, known as gastrinomas, result in the production of too much gastric acid. The excessive acid may cause peptic ulcers in your stomach or intestine, resulting in symptoms such as heartburn, abdominal pain, acid reflux, and vomiting. Zollinger-Ellison syndrome is associated with hereditary conditions.

Symptoms of Zollinger-Ellison syndrome

  • Diarrhea

  • Greasy stools that float, associated with problems with digestion

  • Heartburn; painful burning feeling in the chest or throat

  • Stomach feels bloated

  • Loss of appetite

  • Black, shiny stool

  • Abdominal pain

Questions your doctor may ask to check for Zollinger-Ellison syndrome

Your doctor may ask these questions to diagnose Zollinger-Ellison syndrome

  • Do you have loose stools or diarrhea?

  • Do you have greasy and smelly stools?

  • Do you have heartburn?

  • Do you feel that your abdomen (stomach) is bloated or has a lot of gas?

  • Do you have less or no appetite, therefore eat less food?

Treatment for Zollinger-Ellison syndrome

Treatment of Zollinger-Ellison Syndrome is aimed at surgically removing the tumors and treating the excess acid. In cases where the tumors are numerous or have spread, other methods to control tumor growth may be recommended, like chemotherapy.

View the symptoms of Zollinger-Ellison syndrome

User testimonials

Reviewed By:

Aiko Yoshioka

Aiko Yoshioka, MD (Gastroenterology)

Dr. Yoshioka graduated from the Niigata University School of Medicine. He worked as a gastroenterologist at Saiseikai Niigata Hospital and Niigata University Medical & Dental Hospital before serving as the Deputy Chief of Gastroenterology at Tsubame Rosai Hospital and Nagaoka Red Cross Hospital. Dr. Yoshioka joined Saitama Saiseikai Kawaguchi General Hospital as Chief of Gastroenterology in April 2018.

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