Amyotrophic Lateral Sclerosis Quiz
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Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Learn more about Amyotrophic lateral sclerosis
Content updated on Sep 20, 2022
What is amyotrophic lateral sclerosis?
This is also known as ALS, Lou Gehrig's disease, or motor neuron disease. This is a progressive, degenerative condition that affects the nerve cells of the brain and spinal cord, resulting in loss of muscle control, eventually leading to difficulty eating, breathing and speaking. The exact cause is unknown. It could be due to genetic, environmental, and lifestyle factors.
Symptoms of amyotrophic lateral sclerosis
Recent weight loss
Difficulty pronouncing words
Weakness in arms or legs
Slurred speech
Difficulty standing up from sitting position
Difficulty swallowing food or water
Tongue pain
Questions your doctor may ask to check for amyotrophic lateral sclerosis
Your doctor may ask these questions to diagnose amyotrophic lateral sclerosis
Have you lost weight recently?
Do you have difficulty pronouncing words properly?
Do you feel any weakness in your arms or legs?
Do you have slurred speech?
Do you have difficulty in getting up from a chair on your own?
Treatment for amyotrophic lateral sclerosis
There is no cure for ALS. Medications can reduce the severity of symptoms and slow progression of symptoms. Physical, occupational and/or speech therapy can help improve quality of life.
View the symptoms of Amyotrophic lateral sclerosis
Diseases related to Amyotrophic lateral sclerosis
References
Hardiman O, Al-Chalabi A, Chio A, Corr EM, Logroscino G, Robberecht W, Shaw PJ, Simmons Z, van den Berg LH. Amyotrophic lateral sclerosis. Nat Rev Dis Primers. 2017 Oct 5;3:17071. doi: 10.1038/nrdp.2017.71. Erratum in: Nat Rev Dis Primers. 2017 Oct 20;3:17085. PMID: 28980624.
https://www.nature.com/articles/nrdp201771
Kiernan MC, Vucic S, Cheah BC, Turner MR, Eisen A, Hardiman O, Burrell JR, Zoing MC. Amyotrophic lateral sclerosis. Lancet. 2011 Mar 12;377(9769):942-55. doi: 10.1016/S0140-6736(10)61156-7. Epub 2011 Feb 4. PMID: 21296405.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)61156-7/fulltext
Hulisz D. Amyotrophic lateral sclerosis: disease state overview. Am J Manag Care. 2018 Aug;24(15 Suppl):S320-S326. PMID: 30207670.
https://www.ajmc.com/view/amyotrophic-lateral-sclerosis-disease-state-overview
Grad LI, Rouleau GA, Ravits J, Cashman NR. Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS). Cold Spring Harb Perspect Med. 2017 Aug 1;7(8):a024117. doi: 10.1101/cshperspect.a024117. PMID: 28003278; PMCID: PMC5538408.
http://perspectivesinmedicine.cshlp.org/content/7/8/a024117
Brown RH, Al-Chalabi A. Amyotrophic Lateral Sclerosis. N Engl J Med. 2017 Jul 13;377(2):162-172. doi: 10.1056/NEJMra1603471. PMID: 28700839.
https://www.nejm.org/doi/10.1056/NEJMra1603471
Reviewed By:
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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Obstetrics and gynecology (OBGYN)
National Center for Child Health and Development, Japan