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There are blisters
Redness of the skin
Causing a blister
Red spots on skin
I have blisters on my chin
Skin is red
Blistering
Not seeing your symptoms? No worries!
What is Eosinophilic Cellulitis?
Eosinophilic cellulitis is an inflammatory skin condition with an unknown cause. In this disease, itchy, burning, red, and inflamed areas can form anywhere on the skin. The inflamed areas can look like a skin infection called cellulitis, but there is no true infection present. It may be due to an immune system disorder and could be triggered by insect or tick bites, medications, or surgery.
Typical Symptoms of Eosinophilic Cellulitis
- Blisters on the skin
- Itchy skin
- Redness in the affected area
- Swelling in the affected area
- Insect sting or injury from animals
- Skin problems
- Redness, bumps, or irritation on the skin
- Fever
Diagnostic Questions for Eosinophilic Cellulitis
Your doctor may ask these questions to check for this disease:
- Do you have any blisters on your skin?
- Do you have itchy skin?
- Is the affected area red?
- Do you have swelling in the affected area?
- Have you been bitten or stung by bugs or animals?
Treatment of Eosinophilic Cellulitis
Treatment for eosinophilic cellulitis involves anti-inflammatory and other medications. It typically clears up in a few months.
Reviewed By:
Sarita Nori, MD (Dermatology)
Dr. Sarita Nori was drawn to dermatology because of the intersection of science and medicine that is at the heart of dermatology. She feels this is what really allows her to help her patients. “There is a lot of problem-solving in dermatology and I like that,” she explains. “It’s also a profession where you can help people quickly and really make a difference in their lives.” | Some of the typical skin problems that Dr. Nori treats include skin cancers, psoriasis, acne, eczema, rashes, and contact dermatitis. Dr Nori believes in using all possible avenues of treatment, such as biologics, especially in patients with chronic diseases such as eczema and psoriasis. “These medications can work superbly, and they are really life-changing for many patients.” | Dr. Nori feels it’s important for patients to have a good understanding of the disease or condition that is affecting them. “I like to educate my patients on their problem and have them really understand it so they can take the best course of action. Patients always do better when they understand their skin condition, and how to treat it.”
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Sep 2, 2025
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
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- Itch is mild
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See full list
Symptoms Related to Eosinophilic Cellulitis
Diseases Related to Eosinophilic Cellulitis
FAQs
Q.
High Eosinophils? Why Your Count Is Up + Medically Approved Next Steps
A.
High eosinophils mean your immune system is reacting to something; common causes include allergies, asthma, eczema, parasitic infections, and medication reactions, while persistent counts above 1,500 or very high levels can point to autoimmune or eosinophilic disorders or, rarely, blood cancers. Next steps include reviewing the absolute count and full CBC, checking symptoms, meds, and travel, and following your doctor’s plan for repeat labs, stool tests, allergy evaluation, imaging, or specialist referral, with urgent care needed for chest pain, breathing trouble, fainting, severe swelling, or neurologic symptoms; there are several factors to consider, so see below for complete guidance that can affect which steps you take.
References:
* Lim DB, Weller PF. Approach to the Patient with Eosinophilia. J Allergy Clin Immunol Pract. 2021 Jan;9(1):15-28. doi: 10.1016/j.jaip.2020.09.043. PMID: 33413993.
* Takamoto M, Terui Y. Eosinophilia: An Aid to Diagnosis. Intern Med. 2021 Aug 1;60(15):2333-2339. doi: 10.2169/internalmedicine.7135-20. Epub 2021 Mar 18. PMID: 33737520; PMCID: PMC8379469.
* Gelfand JM, Feske S. Eosinophilia: A Guide for the Neurologist. J Neurol Sci. 2020 Dec 15;419:117180. doi: 10.1016/j.jns.2020.117180. Epub 2020 Oct 13. PMID: 33189397.
* Mohyuddin GR, Alqatari H, Adjei AA. Drug-induced eosinophilia: Clinical presentation and mechanisms. Front Pharmacol. 2022 Sep 12;13:995726. doi: 10.3389/fphar.2022.995726. PMID: 36176548; PMCID: PMC9509204.
* Ogbogu PU, Koster JC, Liu LY, Mullol J, Klion AD, Weller PF, Roufosse F, Cogan E, Gleich GJ, Takematsu H, Arai N, Matsuda H, Shigematsu M, Shimamura T, Tajima M, Yamada A, Yamamoto N, Yoshikawa T, Yu L. Evaluation and Management of Eosinophilia: A Comprehensive Review. J Clin Immunol. 2019 May;39(4):303-315. doi: 10.1007/s10875-019-00624-8. Epub 2019 Apr 1. PMID: 30937549; PMCID: PMC6486430.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Ozturk M, Ucan E, Ibiloglu I. Indian Dermatol Online J. 2019 Jul-Aug;10(4):467-468. doi: 10.4103/idoj.IDOJ_387_18. PMID: 31334073; PMCID: PMC6615380.
https://journals.lww.com/idoj/Fulltext/2019/10040/Eosinophilic_Cellulitis_Successfully_Treated_with.19.aspxYeon J, Chan RC, Zagarella S. Australas J Dermatol. 2020 Nov;61(4):e421-e423. doi: 10.1111/ajd.13358. Epub 2020 Jun 25. PMID: 32585743.
https://onlinelibrary.wiley.com/doi/10.1111/ajd.13358Sinno H, Lacroix JP, Lee J, Izadpanah A, Borsuk R, Watters K, Gilardino M. Diagnosis and management of eosinophilic cellulitis (Wells' syndrome): A case series and literature review. Can J Plast Surg. 2012 Summer;20(2):91-7. doi: 10.1177/229255031202000204. PMID: 23730155; PMCID: PMC3383552.