Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Dec 13, 2024
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Nausea
Malaise
Fatigue
Dehydration
Cottonmouth
Dry mouth
Loss of appetite
Loss of taste and smell
Diarrhea and vomiting
Weight loss
Dehydration headache
Extreme tiredness
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A severe form of morning sickness, where patients have significant vomiting and are typically unable to keep much food or fluids down. They can lose weight and become very dehydrated. The exact cause is unclear, but it's thought to be related to levels of pregnancy hormones (β-hCG and estrogen). Early treatment of morning sickness can help prevent progression to this severe form. There is typically no harm to the developing baby from this condition, but it is important to maintain normal hydration and weight in the mom.
Your doctor may ask these questions to check for this disease:
Treatment depends on the severity of the condition. Some severely dehydrated patients may need hospitalization and fluids given through a needle in the vein (IV fluids). Medications can be given to reduce the nausea and vomiting, and help with tolerance of oral food and fluids. Many patients will have improvement in symptoms as the pregnancy advances into the second and third trimester.
London V, Grube S, Sherer DM, Abulafia O. Hyperemesis Gravidarum: A Review of Recent Literature. Pharmacology. 2017;100(3-4):161-171. doi: 10.1159/000477853. Epub 2017 Jun 23. PMID: 28641304.
https://www.karger.com/Article/FullText/477853Abramowitz A, Miller ES, Wisner KL. Treatment options for hyperemesis gravidarum. Arch Womens Ment Health. 2017 Jun;20(3):363-372. doi: 10.1007/s00737-016-0707-4. Epub 2017 Jan 9. PMID: 28070660; PMCID: PMC7037589.
https://link.springer.com/article/10.1007/s00737-016-0707-4Austin K, Wilson K, Saha S. Hyperemesis Gravidarum. Nutr Clin Pract. 2019 Apr;34(2):226-241. doi: 10.1002/ncp.10205. Epub 2018 Oct 18. PMID: 30334272.
https://onlinelibrary.wiley.com/doi/10.1002/ncp.10205Dean CR, Shemar M, Ostrowski GAU, Painter RC. Management of severe pregnancy sickness and hyperemesis gravidarum. BMJ. 2018 Nov 30;363:k5000. doi: 10.1136/bmj.k5000. PMID: 30504245.
https://www.bmj.com/content/363/bmj.k5000ACOG Practice Bulletin
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2018/01/nausea-and-vomiting-of-pregnancyMale, 30s
I got more answers in one minute through your site than I did in three hours with Google.
(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
(Sep 27, 2024)
Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
(Sep 26, 2024)
Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Our symptom checker AI is continuously refined with input from experienced physicians, empowering them to make more accurate diagnoses.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1