Paroxysmal Nocturnal Hemoglobinuria Quiz

Check your symptoms and
find possible causes with AI for free

Reviewed By:

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

From our team of 50+ doctors

Please choose the symptom you are most concerned about.

It will help us optimise further questions for you.

By starting the symptom checker, you agree to the Privacy Policy and Terms of Use

Find another symptom

How Ubie can help you

With an easy 3-min questionnaire, Ubie's AI-powered system will generate a free report on possible causes.

  • Over 1,000 medical centers, trained by over 50 doctors, and still improving.

  • Questions are customized to your situation and symptoms

  • Paroxysmal nocturnal hemoglobinuria as well as similar diseases can be checked at the same time.

Your symptoms

Input your symptoms

Our AI

Our AI checks your symptoms

Your report

You get your personalized report

Personalized Report

✔︎  When to see a doctor

✔︎  What causes your symptoms

✔︎  Treatment information etc.

People with these symptoms also use Ubie's symptom checker to find possible causes

  • Red-brown urine came out

  • Blood is mixed in pee

  • Pit of the stomach has burning sensation

  • Stomach discomfort and grouchiness comes and goes with fussiness / grouchiness

  • Child starts crying or pushes me away if I try to massage the stomachache area

  • I ate something in the previous 3 days that might be causing symptoms

  • Child can't move around much because it makes the stomach pain worse

Just 3 minutes.
Developed by doctors.

Learn more about Paroxysmal nocturnal hemoglobinuria

Content updated on Nov 2, 2022

What is paroxysmal nocturnal hemoglobinuria?

Paroxysmal nocturnal hemoglobinuria is a rare and life-threatening disease of the blood. The disease is characterized by destruction of red blood cells, blood clots, and impaired bone marrow function.

Symptoms of paroxysmal nocturnal hemoglobinuria

  • Bloody or red urine

  • Abdominal pain

  • Easily fatigued

  • Feeling breathless

Questions your doctor may ask to check for paroxysmal nocturnal hemoglobinuria

Your doctor may ask these questions to diagnose paroxysmal nocturnal hemoglobinuria

  • Have you ever had red or brown urine (hematuria)?

  • Do you have abdominal pain (stomach ache)?

  • Do you get tired easily?

  • Are you breathless or having hard time breathing?

Treatment for paroxysmal nocturnal hemoglobinuria

Treatment depends on the severity of the symptoms. Options include medication therapy and bone marrow transplant.

View the symptoms of Paroxysmal nocturnal hemoglobinuria

References

  • Brodsky RA. Paroxysmal nocturnal hemoglobinuria. Blood. 2014 Oct 30;124(18):2804-11. doi: 10.1182/blood-2014-02-522128. Epub 2014 Sep 18. PMID: 25237200; PMCID: PMC4215311.

    https://ashpublications.org/blood/article/124/18/2804/33385/Paroxysmal-nocturnal-hemoglobinuria

  • Devalet B, Mullier F, Chatelain B, Dogné JM, Chatelain C. Pathophysiology, diagnosis, and treatment of paroxysmal nocturnal hemoglobinuria: a review. Eur J Haematol. 2015 Sep;95(3):190-8. doi: 10.1111/ejh.12543. Epub 2015 Mar 26. PMID: 25753400.

    https://onlinelibrary.wiley.com/doi/10.1111/ejh.12543

  • Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R, Hillmen P, Luzzatto L, Young N, Kinoshita T, Rosse W, Socié G; International PNH Interest Group. Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood. 2005 Dec 1;106(12):3699-709. doi: 10.1182/blood-2005-04-1717. Epub 2005 Jul 28. PMID: 16051736; PMCID: PMC1895106.

    https://ashpublications.org/blood/article/106/12/3699/109767/Diagnosis-and-management-of-paroxysmal-nocturnal

  • Bektas M, Copley-Merriman C, Khan S, Sarda SP, Shammo JM. Paroxysmal nocturnal hemoglobinuria: current treatments and unmet needs. J Manag Care Spec Pharm. 2020 Dec;26(12-b Suppl):S14-S20. doi: 10.18553/jmcp.2020.26.12-b.s14. PMID: 33356783.

    https://www.jmcp.org/doi/10.18553/jmcp.2020.26.12-b.s14

Reviewed By:

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

From our team of 50+ doctors

Just 3 minutes.
Developed by doctors.

Ubie is supervised by 50+ medical experts worldwide

Shohei Harase

Shohei Harase, MD

Neurology

Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD

Psychiatry

Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

View our medical experts