Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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RPC reviewer comment - the new name for this condition is 'Primary Ovarian Insuffiency' Normal menopause starts between the ages of 45 and 55. When it occurs too early (under 40 years old), it is called primary ovarian insufficiency. Causes can include genetic disorders, or medical treatments such as chemotherapy. Certain tests are recommended for evaluation, but in 90% of cases, no clear cause is identified.
Your doctor may ask these questions to check for this disease:
Treatment for this condition aims to correct hormone imbalances and protect organs such as the heart and bones until the age of normal menopause. This may be achieved through hormone replacement therapy. The doctor may also prescribe Vitamin D and calcium supplements to prevent bone weakening. The younger the onset of 'Primary Ovarian Insufficiency', the more likely treatment by a specialist will be recommended.
Kawamura K, Kawamura N, Hsueh AJ. Activation of dormant follicles: a new treatment for premature ovarian failure? Curr Opin Obstet Gynecol. 2016 Jun;28(3):217-22. doi: 10.1097/GCO.0000000000000268. PMID: 27022685; PMCID: PMC5536116.
https://journals.lww.com/co-obgyn/Abstract/2016/06000/Activation_of_dormant_follicles__a_new_treatment.14.aspxBarlow DH. Premature ovarian failure. Baillieres Clin Obstet Gynaecol. 1996 Sep;10(3):361-84. doi: 10.1016/s0950-3552(96)80020-4. PMID: 8931900.
https://www.sciencedirect.com/science/article/abs/pii/S0950355296800204?via%3DihubOBG Project
https://www.obgproject.com/2023/02/13/primary-ovarian-insufficiency-how-to-evaluate-and-make-the-diagnosis/ACOG Committee Opinion
https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2014/07/primary-ovarian-insufficiency-in-adolescents-and-young-womenMale, 30s
I got more answers in one minute through your site than I did in three hours with Google.
(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
(Sep 27, 2024)
Male, 50s
The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
(Sep 26, 2024)
Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Our symptom checker AI is continuously refined with input from experienced physicians, empowering them to make more accurate diagnoses.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1