Primary Ovarian Insufficiency Quiz
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Can't get pregnant
I have trouble with my period
Missed period
A lot of night sweats
Difficulty conceiving
Spotting
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What is Primary Ovarian Insufficiency?
Normal menopause starts between the ages of 45 and 55. When it occurs early (under 40 years old), it is called primary ovarian insufficiency. Causes can include genetic disorders, or medical treatments such as chemotherapy. Certain tests are recommended for evaluation, but in 90% of cases, no clear cause is identified.
Typical Symptoms of Primary Ovarian Insufficiency
- Hot flashes
- Sweating at night requiring change in clothing
- No periods for one year
- History of radiation therapy
- Irregular periods
- Decreased vaginal discharge
- Difficulty getting pregnant
- Unusually heavy or prolonged periods
Diagnostic Questions for Primary Ovarian Insufficiency
Your doctor may ask these questions to check for this disease:
- Are you experiencing hot flashes?
- Do you excessively sweat at night and need to change clothes?
- Did you have your last period over a year ago?
- Have you ever had radiation therapy?
- Are your periods irregular?
Treatment of Primary Ovarian Insufficiency
Treatment for this condition aims to correct hormone imbalances and protect organs such as the heart and bones until the age of normal menopause. This may be achieved through hormone replacement therapy. The doctor may also prescribe Vitamin D and calcium supplements to prevent bone weakening. The younger the onset of 'Primary Ovarian Insufficiency', the more likely treatment by a specialist will be recommended.
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Dec 13, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Very sweaty at night
- Irregular periods
- Very heavy sweating during sleep
- Drenching night sweats
- Absent periods
- Night sweats soaking clothes
- Sheets get wet with sweat at night
- Two periods in one month
- Periods occurring more frequently than 24 days
- Periods occurring too frequently
- Menstrual disorder
- Menstruation has not occured
- No periods for the past few months
- Menstruation stopped
- Infrequent periods (fewer than 6-8 a year)
See full list
Symptoms Related to Primary Ovarian Insufficiency
Diseases Related to Primary Ovarian Insufficiency
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Kawamura K, Kawamura N, Hsueh AJ. Activation of dormant follicles: a new treatment for premature ovarian failure? Curr Opin Obstet Gynecol. 2016 Jun;28(3):217-22. doi: 10.1097/GCO.0000000000000268. PMID: 27022685; PMCID: PMC5536116.
https://journals.lww.com/co-obgyn/Abstract/2016/06000/Activation_of_dormant_follicles__a_new_treatment.14.aspxBarlow DH. Premature ovarian failure. Baillieres Clin Obstet Gynaecol. 1996 Sep;10(3):361-84. doi: 10.1016/s0950-3552(96)80020-4. PMID: 8931900.
https://www.sciencedirect.com/science/article/abs/pii/S0950355296800204?via%3DihubOBG Project
https://www.obgproject.com/2023/02/13/primary-ovarian-insufficiency-how-to-evaluate-and-make-the-diagnosis/ACOG Committee Opinion
https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2014/07/primary-ovarian-insufficiency-in-adolescents-and-young-women