Primary Amenorrhea Quiz
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I have trouble with my period
Delayed puberty
Menstrual delay
No testicular enlargement
Irregular periods
Lack of secondary sexual characteristics
Menstruation is delayed
Not seeing your symptoms? No worries!
What is Primary Amenorrhea?
A condition where menarche (first period for a girl) does not occur on time. Typically absence of first period by age 15 is considered abnormal, but this does vary by ethnicity and location. Causes include problems with malnutrition, genetic disorders, formation of the reproductive system and hormonal imbalances. Primary amenorrhea typically needs evaluation with a specialist to find the correct diagnosis and treatment.
Typical Symptoms of Primary Amenorrhea
- Voice has become lower, deeper
- Irregular periods
- Late or incomplete puberty
- Excessive hair growth on the body
- Swelling in any body part
- Arm bending outward at elbow
- Stomach or abdominal pain
Diagnostic Questions for Primary Amenorrhea
Your doctor may ask these questions to check for this disease:
- Has your voice gotten deeper lately?
- Are your periods irregular?
- Did you experience delayed or absent puberty, delayed development of sexual characteristics?
- Has your body hair thickened recently?
- Is there swelling in any body part?
Treatment of Primary Amenorrhea
Treatment depends on the cause. For example, hormone imbalances may be corrected by hormone therapy, and malnourishment can be corrected with improved diet.
Reviewed By:
Ravi P. Chokshi, MD (Obstetrics and Gynecology (OBGYN), Critical Care)
Current Maternal Fetal Medicine Fellow with Dual board certification in Obstetrics & Gynecology and Critical Care Medicine. | 5+ years experience managing a general Ob/Gyn practice and working in the Intensive Care Unit. | Previously Physician Lead of a large single specialty practice with 8 Physicians and 10+ Advanced practitioners. | Member of the Society of Maternal Fetal Medicine Patient education committee. | Frequent Medscape Consult contributor.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- My voice is changing
- My voice is lower than normal
- Voice lowered
- Excessive hair growth on the body
- Absent periods
- My voice is deeper than normal
- Swelling
- Deep voice
- Underdeveloped external genitalia
- Hirsutism
- Two periods in one month
- Swollen feet
- Periods occurring more frequently than 24 days
- Thick, dark hair on face, neck, chest, tummy, lower back, buttocks or thighs
- Periods occurring too frequently
See full list
Symptoms Related to Primary Amenorrhea
Diseases Related to Primary Amenorrhea
FAQs
Q.
The "Double Period" Panic: Why Your Cycle Just Restarted with a Vengeance (And When to Worry)
A.
Bleeding twice in a month or a sudden heavy period after a gap is usually due to temporary hormonal shifts from stress, birth control changes, anovulatory or early ovulation cycles, or secondary amenorrhea, and many cycles settle within a few months. There are several factors to consider, and you should seek care if bleeding lasts more than 7 to 10 days, you soak pads hourly, pass large clots, have severe pain or dizziness, bleed after sex, notice sudden changes after 40, or pregnancy is possible; see below for other causes like thyroid disease, PCOS, fibroids, what to track, and how doctors evaluate this.
References:
* Johnson JLR, Johnson LEC. Intermenstrual Bleeding. [Updated 2023 Jun 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: pubmed.ncbi.nlm.nih.gov/34091642/
* Khan SA, Malik S, Zahid S. Abnormal Uterine Bleeding: Evaluation and Management. [Updated 2024 Jan 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: pubmed.ncbi.nlm.nih.gov/35593806/
* Reed BG, Carr BR. Physiology, Menstrual Cycle. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: pubmed.ncbi.nlm.nih.gov/29261864/
* Veldhuis JD, Veldhuis P, Veldhuis N. Luteal Phase Deficiency: A Systematic Review. Front Endocrinol (Lausanne). 2016 Apr 25;7:43. doi: 10.3389/fendo.2016.00043. PMID: 27170817; PMCID: PMC4842914. Available from: pubmed.ncbi.nlm.nih.gov/27170817/
* Teede HJ, Misso ML, Costello MF, et al. Polycystic Ovary Syndrome: Pathophysiology, Diagnosis and Treatment. Med J Aust. 2021 Jan;214(1):3-9. doi: 10.5694/mja2.50851. Epub 2021 Jan 11. PMID: 33499427. Available from: pubmed.ncbi.nlm.nih.gov/33499427/
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Marsh CA, Grimstad FW. Primary amenorrhea: diagnosis and management. Obstet Gynecol Surv. 2014 Oct;69(10):603-12. doi: 10.1097/OGX.0000000000000111. PMID: 25336070.
https://journals.lww.com/obgynsurvey/Abstract/2014/10000/Primary_Amenorrhea__Diagnosis_and_Management.18.aspxACOG Patient FAQ
https://www.acog.org/womens-health/faqs/amenorrhea-absence-of-periods#:~:text=Amenorrhea%20is%20the%20absence%20of,for%203%20months%20or%20more.NIH - Stat Pearls
https://www.ncbi.nlm.nih.gov/books/NBK554469/