Tuberous Sclerosis Quiz
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Rashes
Facial skin problems
Cutaneous angiofibromas of the face
Redness of the skin
Tooth loss near the base
Many skin nodules
Swelling under the nail
Not seeing your symptoms? No worries!
What is Tuberous Sclerosis?
A rare disease caused by genetic mutations that leads to non-cancerous tumors or growths in the brain and other organs. Symptoms can vary widely based on the severity and location of the tumor.
Typical Symptoms of Tuberous Sclerosis
- Unable to speak, although I understand what people are saying
- Difficulty speaking, performing tasks, or recognizing things
- Seizure
- Writing difficulties
- Lump(s) growing on your gums
- Lump under or around the nail
- Many lumps appearing on the skin
- Recent changes in mental state
Diagnostic Questions for Tuberous Sclerosis
Your doctor may ask these questions to check for this disease:
- Can you understand others but struggle to express yourself clearly?
- Have you been experiencing difficulty speaking, performing tasks, or recognizing things?
- Have you experienced any seizures?
- Have you been experiencing difficulties with writing?
- Are there any lumps on your gums?
Treatment of Tuberous Sclerosis
There is no cure for tuberous sclerosis. Treatment focuses on managing symptoms, such as using anti-seizure medications to control seizures in tuberous sclerosis.
Reviewed By:
Caroline M. Doan, DO (Internal Medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Antisocial behavior and language difficulty
- My body is jerking
- Dysgraphia
- Can't say what I want to say
- Twitching
- Problems remembering
- Writing disorder
- Speech is difficult and requires conscious effort
- Fever seizures (with fever of >100.4°F / 38°C)
- Can't read words like I used to
- Agraphia
- Seizures without fever
- Can't perform tasks
- Started having reading difficulty as an adult
- The first seizure
See full list
Symptoms Related to Tuberous Sclerosis
Diseases Related to Tuberous Sclerosis
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Randle SC. Tuberous Sclerosis Complex: A Review. Pediatr Ann. 2017 Apr 1;46(4):e166-e171. doi: 10.3928/19382359-20170320-01. PMID: 28414398.
https://journals.healio.com/doi/10.3928/19382359-20170320-01Portocarrero LKL, Quental KN, Samorano LP, Oliveira ZNP, Rivitti-Machado MCDM. Tuberous sclerosis complex: review based on new diagnostic criteria. An Bras Dermatol. 2018 Jun;93(3):323-331. doi: 10.1590/abd1806-4841.20186972. PMID: 29924239; PMCID: PMC6001077.
https://www.scielo.br/j/abd/a/qvXj7GRvVrCX7FrXZKtSBRz/?lang=enCuratolo P, Bombardieri R, Jozwiak S. Tuberous sclerosis. Lancet. 2008 Aug 23;372(9639):657-68. doi: 10.1016/S0140-6736(08)61279-9. PMID: 18722871.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61279-9/fulltextIslam MP. Tuberous Sclerosis Complex. Semin Pediatr Neurol. 2021 Apr;37:100875. doi: 10.1016/j.spen.2021.100875. Epub 2021 Feb 11. PMID: 33892851.
https://www.sciencedirect.com/science/article/abs/pii/S1071909121000036?via%3Dihub