Reviewed By:
Bret Mobley, MD, MS (Neuropathology)
Dr. Mobley graduated from the University of Michigan Medical School, completing a masters degree in neuroscience between his second and third years of medical school. He trained as a resident in pathology at Stanford University Hospital before joining the faculty of Vanderbilt University Medical Center in Nashville Tennessee in 2010. He was promoted to Associate Professor in 2018 and to Neuropathology Division Director in 2020.
Yu Shirai, MD (Psychiatry)
Dr. Shirai works at the Yotsuya Yui Clinic for mental health treatment for English and Portuguese-speaking patients. He treats a wide range of patients from neurodevelopmental disorders to dementia in children and participates in knowledge sharing through the Diversity Clinic.
Content updated on Feb 6, 2025
Following the Medical Content Editorial Policy
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Try one of these related symptoms.
Tired all the time
Lack of motivation
Emotional numbness
No energy
Social anhedonia
Emotionally detached
Social withdrawal
Lost interest in hobbies
Lost interest in people
Become indifferent
Avoiding everyone
No pleasure in doing things
With a free 3-min quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.
This questionnaire is customized to your situation and symptoms, including the following personal information:
Biological Sex - helps us provide relevant suggestions for male vs. female conditions.
Age - adjusts our guidance based on any age-related health factors.
History - considers past illnesses, surgeries, family history, and lifestyle choices.
Your symptoms
Our AI
Your report
Your personal report will tell you
✔ When to see a doctor
✔︎ What causes your symptoms
✔︎ Treatment information etc.
Generally, Lost interest in people can be related to:
A group of disorders involving the progressive loss of nerve cells in the frontal and temporal lobes of the brain (behind your forehead and ears). The brain shrinks and loses function in the affected areas. It can be caused by several conditions that are not fully understood. A family history of dementia increases the risk.
Mild cognitive impairment (MCI) is also known as mild or "pre-dementia" in which patients experience forgetfulness or other cognitive problems (such as issues with language or thinking) that do not prevent them from daily functioning. A small proportion of patients have MCI due to depression, medication side effects, sleep disturbances such as sleep apnea, low vitamin B12 levels or low thyroid function. Some controllable risk factors include excessive alcohol intake, high blood pressure, lack of exercise, as well as lack of mental stimulation. Patients with MCI have a high risk for developing dementia, which occurs in about 14% of cases.
Sometimes, Lost interest in people may be related to these serious diseases:
This refers to blood collecting in the space between the brain and the brain's outer covering (dura). It can be caused by even minor injuries or bumps to the head, particularly in those who are at increased risk. Older adults and those on certain blood-thinning medications or with bleeding disorders are at higher risk. Some people will have no or few symptoms but can develop more symptoms (confusion, headaches, personality changes) if it expands.
Your doctor may ask these questions to check for this symptom:
We would love to help them too.
Reviewed By:
Bret Mobley, MD, MS (Neuropathology)
Dr. Mobley graduated from the University of Michigan Medical School, completing a masters degree in neuroscience between his second and third years of medical school. He trained as a resident in pathology at Stanford University Hospital before joining the faculty of Vanderbilt University Medical Center in Nashville Tennessee in 2010. He was promoted to Associate Professor in 2018 and to Neuropathology Division Director in 2020.
Yu Shirai, MD (Psychiatry)
Dr. Shirai works at the Yotsuya Yui Clinic for mental health treatment for English and Portuguese-speaking patients. He treats a wide range of patients from neurodevelopmental disorders to dementia in children and participates in knowledge sharing through the Diversity Clinic.
Our symptom checker AI is continuously refined with input from experienced physicians, empowering them to make more accurate diagnoses.
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https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1