Reviewed By:
Caroline M. Doan, DO (Internal Medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
Content updated on Mar 31, 2024
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Cryptococcosis is a potentially life-threatening fungal infection caused by the Cryptococcus species. The main species causing illness in humans is Cryptococcus neoformans, while infections by Cryptococcus gattii are rarer. The fungus is typically found in soil, on decaying wood, in tree hollows, or in bird droppings. Infections are rare in healthy people; most cases occur in those with weakened immune systems, particularly those with advanced HIV/AIDS. Infection can appear in the lungs, presenting as pneumonia, and the brain, presenting as meningitis; in some cases, infection may not show any symptoms.
Your doctor may ask these questions to check for this disease:
Treatment involves antifungal medication to treat the infection and medications to reduce symptoms.
Maziarz EK, Perfect JR. Cryptococcosis. Infect Dis Clin North Am. 2016 Mar;30(1):179-206. doi: 10.1016/j.idc.2015.10.006. PMID: 26897067; PMCID: PMC5808417.
https://www.sciencedirect.com/science/article/abs/pii/S0891552015000951?via%3DihubNoguchi H, Matsumoto T, Kimura U, Hiruma M, Kusuhara M, Ihn H. Cutaneous Cryptococcosis. Med Mycol J. 2019;60(4):101-107. doi: 10.3314/mmj.19.008. PMID: 31787730.
https://www.jstage.jst.go.jp/article/mmj/60/4/60_19.008/_articleSetianingrum F, Rautemaa-Richardson R, Denning DW. Pulmonary cryptococcosis: A review of pathobiology and clinical aspects. Med Mycol. 2019 Feb 1;57(2):133-150. doi: 10.1093/mmy/myy086. PMID: 30329097.
https://academic.oup.com/mmy/article/57/2/133/5133472Henao-Martínez AF, Chastain DB, Franco-Paredes C. Treatment of cryptococcosis in non-HIV immunocompromised patients. Curr Opin Infect Dis. 2018 Aug;31(4):278-285. doi: 10.1097/QCO.0000000000000458. PMID: 29738314.
https://journals.lww.com/co-infectiousdiseases/Abstract/2018/08000/Treatment_of_cryptococcosis_in_non_HIV.4.aspxPennisi MG, Hartmann K, Lloret A, Ferrer L, Addie D, Belák S, Boucraut-Baralon C, Egberink H, Frymus T, Gruffydd-Jones T, Hosie MJ, Lutz H, Marsilio F, Möstl K, Radford AD, Thiry E, Truyen U, Horzinek MC. Cryptococcosis in cats: ABCD guidelines on prevention and management. J Feline Med Surg. 2013 Jul;15(7):611-8. doi: 10.1177/1098612X13489224. PMID: 23813826.
https://journals.sagepub.com/doi/10.1177/1098612X13489224Male, 30s
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(Sep 29, 2024)
Male, 20s
My experience was great. I was worried, but the symptom checker helped me narrow down what it might be. I feel a little relieved compared to when I first started, and it gives me a starting point for what my symptoms could mean.
(Sep 27, 2024)
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The questions asked and possible causes seemed spot on, putting me at ease for a next-step solution.
(Sep 26, 2024)
Female, 40s
I was actually very impressed with the results it provided because, although I didn’t mention it during the questionnaire because I thought it was unrelated, it suggested I may have something I’ve actually been diagnosed with in the past.
(Sep 25, 2024)
Reviewed By:
Caroline M. Doan, DO (Internal Medicine)
Dr. Doan received a Bachelor of Science degree with honors from UCLA. Prior to obtaining her medical degree, she was involved in oncology clinical research at City of Hope, a National Cancer Institute-designated comprehensive cancer center in southern California. She attended medical school at Touro University California, and completed her residency in Internal Medicine at Oregon Health & Science University. She is certified by the American Board of Internal Medicine and holds an active medical license in several states. She currently works as a physician for Signify Health providing home-based health care.
Shohei Harase, MD (Neurology)
Dr. Harase spent his junior and senior high school years in Finland and the U.S. After graduating from the University of Washington (Bachelor of Science, Molecular and Cellular Biology), he worked for Apple Japan Inc. before entering the University of the Ryukyus School of Medicine. He completed his residency at Okinawa Prefectural Chubu Hospital, where he received the Best Resident Award in 2016 and 2017. In 2021, he joined the Department of Cerebrovascular Medicine at the National Cerebral and Cardiovascular Center, specializing in hyperacute stroke.
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