Erythema Infectiosum (Slapped Cheek Syndrome) Quiz
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Skin is mottled like lace or a fish net
Have a fever
Redness of the skin
Burning sensation in the joints
Cough
Red rashes on cheeks
Not seeing your symptoms? No worries!
What is Erythema Infectiosum (Slapped Cheek Syndrome)?
Fifth disease (erythema infectiosum) is a childhood condition that appears as a bright red rash on your child’s cheeks. It’s nicknamed “slapped cheek disease” because of this rash. A virus called parvovirus B19 causes fifth disease. This virus is common and very contagious. Infected people can spread it through coughing or sneezing. A second rash can appear on the arms, legs, or back.
Typical Symptoms of Erythema Infectiosum (Slapped Cheek Syndrome)
- Red rash over cheeks
- Fever
- Red skin with lace-like pattern
- Cough
- Fever that started after cold or stomach symptoms
- Warmth in the joints
- Hot flashes
- Headache
Diagnostic Questions for Erythema Infectiosum (Slapped Cheek Syndrome)
Your doctor may ask these questions to check for this disease:
- Do you have red rashes on your cheeks?
- Do you have a fever?
- Do you have red skin with a lace-like pattern?
- Do you have a cough?
- Did your fever start after having cold or stomach symptoms?
Treatment of Erythema Infectiosum (Slapped Cheek Syndrome)
Fifth disease isn’t a serious medical condition. Most children do not need any treatment, except for rest to allow the body to fight the infection.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Yukiko Ueda, MD (Dermatology)
Dr. Ueda graduated from the Niigata University School of Medicine and trained at the University of Tokyo Medical School. She is currently a clinical assistant professor at the Department of Dermatology, Jichi Medical University, and holds several posts in the dermatology departments at Kyoto Prefectural University of Medicine, Komagome Hospital, University of Tokyo, and the Medical Center of Japan Red Cross Society.
Content updated on Feb 19, 2025
Following the Medical Content Editorial Policy
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Servey JT, Reamy BV, Hodge J (Year). Clinical presentations of parvovirus B19 infection. American family physician.
https://pubmed.ncbi.nlm.nih.gov/17304869/Leung AKC, Lam JM, Barankin B, Leong KF, Hon KL (Year). Erythema Infectiosum: A Narrative Review. Current pediatric reviews.
https://pubmed.ncbi.nlm.nih.gov/37132144/Grossman KL, Rasmussen JE (Year). Recent advances in pediatric infectious diseases and their impact on dermatology. Journal of the American Academy of Dermatology.
https://pubmed.ncbi.nlm.nih.gov/2061433/