Fatigue (Overwork) Quiz
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Fatigued
Depressed
Inability to sleep
Fatigue
Sadness
Can't sleep
Feel weak
Not seeing your symptoms? No worries!
What is Fatigue (Overwork)?
Fatigue results from the buildup of mental stress and physical tiredness.
Typical Symptoms of Fatigue (Overwork)
- Episodes of sudden, overwhelming daytime sleepiness
- Difficulty concentrating
- Fatigue or low energy that is worse in the morning
- Persistent fatigue and lack of motivation
- Decreased motivation
- Feeling down or depressed
- Trouble sleeping
- Recent weight loss
Diagnostic Questions for Fatigue (Overwork)
Your doctor may ask these questions to check for this disease:
- Do you have episodes of sudden, overwhelming daytime sleepiness?
- Do you have difficulty concentrating?
- Do you experience fatigue or low energy that is worse in the morning?
- Have you been experiencing persistent fatigue and lack of motivation?
- Have you been experiencing decreased motivation recently?
Treatment of Fatigue (Overwork)
To treat this condition, address the cause. Reduce the workload and ensure sufficient mental and physical rest.
Reviewed By:
Scott Nass, MD, MPA, FAAFP, AAHIVS (Primary Care)
Dr. Nass received dual medical degrees from the David Geffen School of Medicine at UCLA and Charles R. Drew University in Medicine and Science. He completed Family Medicine residency at Ventura County Medical Center with subsequent fellowships at Ventura, University of North Carolina-Chapel Hill, George Washington University, and University of California-Irvine. He holds faculty appointments at Keck School of Medicine of USC, Loma Linda University School of Medicine, and Western University of Health Sciences.
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Feb 13, 2025
Following the Medical Content Editorial Policy
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People with similar symptoms also use Ubie's symptom checker to find possible causes
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- Making careless mistakes
- Fewer creative urges nowadays
- I can't continue one thing
See full list
Symptoms Related to Fatigue (Overwork)
Diseases Related to Fatigue (Overwork)
FAQs
Q.
Always Tired? Why Your Glycogen Is Low & Medically Approved Next Steps
A.
Feeling constantly tired can be due to low glycogen, the quick energy your liver and muscles store, which gets drained by skipped meals, low carb dieting, hard workouts, poor sleep, dehydration, and chronic stress, causing fatigue, brain fog, weakness, shakiness, cravings, and reduced performance. Medically approved fixes include regular balanced meals with whole food carbohydrates, pairing carbs with protein and healthy fats, timing fuel around activity, hydrating, prioritizing 7 to 9 hours of sleep, managing stress, and avoiding extreme diets. Because serious conditions can also cause fatigue, seek medical care for persistent or severe symptoms or red flags like chest pain, shortness of breath, dizziness or fainting, unexplained weight loss, or severe weakness; see below for the complete step by step plan, nuances, and tests to discuss with your clinician.
References:
* Hawley, J. A., & Zierath, J. R. (2019). The Role of Glycogen in Exercise Performance and Metabolism. *Comprehensive Physiology*, *10*(1), 1-18.
* Hargreaves, M., & Spriet, L. L. (2020). Skeletal Muscle Energy Metabolism During Exercise. *Nature Metabolism*, *2*(9), 817-828.
* Murray, B., & Rosenbloom, C. (2018). Fundamentals of Carbohydrate Metabolism and Glycogen. *Nutrition in Clinical Practice*, *33*(2), 273-287.
* Rui, L. (2014). Energy Metabolism in the Liver. *Comprehensive Physiology*, *4*(1), 177-197.
* Van Cauwenberghe, K., Van Roie, E., Vancampfort, D., Opdebeeck, C., De Hert, M., & De Bruyn, L. (2020). The Interplay Between Metabolic Syndrome and Chronic Fatigue. *Frontiers in Endocrinology*, *11*, 598.
Q.
Always Weak? Why Your Cells Are Starving for Creatine Monohydrate + Medically Approved Next Steps
A.
There are several factors to consider, and more context is outlined below: persistent weakness can reflect low cellular energy with suboptimal creatine availability, and creatine monohydrate helps regenerate ATP to support strength, stamina, and cognition when the basics like sleep, nutrition, hydration, and resistance training are in place. Medically approved next steps include ruling out red flags with your clinician and basic labs, then if cleared trying 3-5 g daily of plain creatine monohydrate with good hydration and 6-8 weeks of monitoring, while avoiding unsupervised use if you have kidney or liver disease or other risks; important details and red flags are listed below.
References:
* Kreider RB, et al. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017 Jun 13;14:18. doi: 10.1186/s12970-017-0173-z. PMID: 28615996; PMCID: PMC5469049.
* Daly RM, et al. The creatine kinase/creatine system in the skeletal muscle of mammals. Cell Mol Life Sci. 2018 Mar;75(5):857-869. doi: 10.1007/s00018-017-2680-3. Epub 2017 Oct 28. PMID: 29462791.
* Kley RA, et al. Oral creatine monohydrate supplementation for neuromuscular diseases. Cochrane Database Syst Rev. 2013 Jun 20;2013(6):CD004760. doi: 10.1002/14651858.CD004760.pub3. PMID: 23793747; PMCID: PMC6483562.
* Gualano B, et al. Effects of creatine supplementation on muscular performance and body composition in healthy older adults: an updated systematic review and meta-analysis. Eur J Clin Nutr. 2022 Sep;76(9):1233-1246. doi: 10.1038/s41430-022-01129-2. Epub 2022 May 2. PMID: 35501306.
* Antonio J, et al. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? J Int Soc Sports Nutr. 2021 Feb 8;18(1):13. doi: 10.1186/s12970-021-00412-w. PMID: 33557850; PMCID: PMC7873528.
Q.
Is It Just Stress? Why Your Brain Feels Like Lead and Medically Approved Next Steps
A.
A heavy, lead-like brain can come from chronic stress, depression, poor sleep, burnout, or medical issues like thyroid problems, anemia, vitamin B12 deficiency, sleep apnea, diabetes, or medication effects; stress often eases with rest and clear triggers, while depression persists 2 or more weeks with low mood or loss of interest despite rest. Medically approved next steps include a doctor visit for labs and sleep evaluation, a depression screening, targeted stress reduction, and restoring basics like consistent sleep, brief daily movement, regular meals, morning light, and social connection, with urgent care for any self-harm thoughts. There are several factors to consider; see below for specific signs, decision points, and treatments that can change which next steps are right for you.
References:
* Alkadhi, K. A., Alattar, A. M., & Qasem, M. A. (2021). Stress, fatigue, and cognitive performance: a systematic review. *Journal of Clinical Neuroscience*, *87*, 170-176.
* Finsterer, J., & Mahlberg, R. (2022). Fatigue: A Review of Clinical Presentation, Pathophysiology, and Treatment. *Journal of Clinical Medicine*, *11*(13), 3684.
* Morris, G., & Morris, M. C. (2020). The neurobiological basis of chronic fatigue syndrome. *Brain Sciences*, *10*(10), 738.
* Chaudhuri, A., & Chaudhuri, J. (2022). Chronic fatigue syndrome/myalgic encephalomyelitis: Challenges in diagnosis and management. *Clinical Medicine (London, England)*, *22*(4), 369-373.
* Nacul, L. C., Lacerda, E. M., & Kingdon, C. C. (2021). Management of chronic fatigue: an overview of systematic reviews. *Fatigue: Biomedicine, Health & Behavior*, *9*(3), 195-212.
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Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Rodrigues, H., Cobucci, R., Oliveira, A., & Cabral, J. V. (2018). Burnout syndrome among medical residents: A systematic review and meta-analysis. PloS one.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206840García-Carmona, M., Marín, M. D., & Aguayo, R. (2019). Burnout syndrome in secondary school teachers: A systematic review and meta-analysis. Social Psychology of.
https://link.springer.com/article/10.1007/s11218-018-9471-9Maslach, C., & Leiter, M. P. (2016). Burnout. Stress: Concepts, cognition, emotion, and behavior.
https://www.sciencedirect.com/science/article/pii/B9780128009512000443