Uterine Hypoplasia Quiz
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Can't get pregnant
Absent periods
I have trouble with my period
Missed period
Delayed puberty
Decreased period bleed
Difficulty conceiving
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What is Uterine Hypoplasia?
Uterine hypoplasia, also known as a hypoplastic uterus, occurs when a girl is born with an abnormally small uterus. Symptoms may include failure to start having periods at puberty (primary amenorrhea), abdominal pain, a small or no vaginal opening, or infertility.
Typical Symptoms of Uterine Hypoplasia
- Long intervals between periods e.g. 39 days or more
- Hardly any bleeding during periods
- Difficulty becoming pregnant for more than a year despite trying
- Irregular periods
- Late or incomplete puberty
- Difficulty getting pregnant
- Unusual changes in period
- No periods for one year
Diagnostic Questions for Uterine Hypoplasia
Your doctor may ask these questions to check for this disease:
- Is your menstrual cycle infrequent?
- Do you hardly have any bleeding during your periods?
- Have you been trying to become pregnant for more than a year without success?
- Are your periods irregular?
- Did you experience delayed or absent puberty, delayed development of sexual characteristics?
Treatment of Uterine Hypoplasia
Treatment varies based on symptoms. Uterine hypoplasia is typically caused by pubertal failure and may be treated with puberty induction using estrogens and/or progestogens.
Reviewed By:
Unnati Patel, MD, MSc (Family Medicine)
Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.
Seiji Kanazawa, MD, PHD (Obstetrics and Gynecology (OBGYN))
Dr. Kanazawa graduated from the Niigata University Faculty of Medicine and received his Ph.D. from the Tohoku University Graduate School of Medicine. He is working on the front line of the General Perinatal Center, including the Tokyo Tama General Medical Center and the National Center for Research in Fertility Medicine, where he provides maternal and fetal care and undertakes clinical research. At Ubie, Dr. Kanazawa has been designing the Ubie AI Symptom Checker and has taken on the role of general obstetrics and gynecology consultation at FMC Tokyo Clinic by providing fetal ultrasound and prenatal consultation.
Content updated on Feb 19, 2025
Following the Medical Content Editorial Policy
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Uterine Hypoplasia?
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People with similar symptoms also use Ubie's symptom checker to find possible causes
- Irregular periods
- Underdeveloped external genitalia
- Menstrual delay
- Lack of secondary sexual characteristics
- Two periods in one month
- No testicular enlargement
- Periods occurring more frequently than 24 days
- Periods occurring too frequently
- Small or absent prostate
- Menstrual disorder
- No pubic hair
- Menstruation has not occured
- Menstruation did not occur
- No periods for the past few months
- Never had voice change
See full list
Symptoms Related to Uterine Hypoplasia
Diseases Related to Uterine Hypoplasia
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Which is the best Symptom Checker?
Ubie’s symptom checker demonstrated a Top-10 hit accuracy of 71.6%, surpassing the performance of several leading symptom checkers in the market, which averaged around 60% accuracy in similar assessments.
Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Jing R, Kong Y, Han G, Zhang J, Li K, Dong X, Yan J, Zhang H, Han J, Feng L (2020). The Mutation of the Ap3b1 Gene Causes Uterine Hypoplasia in Pearl Mice. Reproductive sciences (Thousand Oaks, Calif.).
https://pubmed.ncbi.nlm.nih.gov/32016796/Simmen RC, Eason RR, McQuown JR, Linz AL, Kang TJ, Chatman L, Till SR, Fujii-Kuriyama Y, Simmen FA, Oh SP (2004). Subfertility, uterine hypoplasia, and partial progesterone resistance in mice lacking the Kruppel-like factor 9/basic transcription element-binding protein-1 (Bteb1) gene. The Journal of biological chemistry.
https://pubmed.ncbi.nlm.nih.gov/15117941/Nahum GG (1998). Uterine anomalies. How common are they, and what is their distribution among subtypes? The Journal of reproductive medicine.
https://pubmed.ncbi.nlm.nih.gov/9800671/