Vitamin B12 Deficiency Quiz

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Scott Nass

Scott Nass, MD, MPA, FAAFP, AAHIVS (GP / Family doctor)

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Learn more about Vitamin B12 deficiency

Content updated on Sep 20, 2022

What is vitamin B12 deficiency?

Vitamin B12 deficiency anemia is deficiency of vitamin B12 resulting in insufficient healthy red blood cells. Vitamin B12 is required for the production of red blood cells, which transport oxygen in the body. It can be a result of insufficient B12 in the the diet or inability to absorb B12 in the small intestine, also called pernicious anemia.

Symptoms of vitamin B12 deficiency

  • Noisy breathing; e.g. wheezing, rattling

  • Unable to, or have difficulty feeling pain

  • Recent weight loss

  • Feel the heart is pounding

  • Intermittent, crampy abdominal pain

  • Recent changes in mental state

  • Abnormalities in sense of taste

  • Hands and legs became clumsy - I cannot do fine work with them

Questions your doctor may ask to check for vitamin B12 deficiency

Your doctor may ask these questions to diagnose vitamin B12 deficiency

  • Is your breathing noisy; e.g. wheezing, rattling?

  • Are you unable to, or have difficulty feeling pain?

  • Have you lost weight recently?

  • Do you feel your heart is pounding?

  • Do you have an abdominal (tummy) pain that comes and goes?

Treatment for vitamin B12 deficiency

Treatment involves dietary modifications, or vitamin B12 supplements in the form of oral medication or injections.

View the symptoms of Vitamin B12 deficiency


  • Herrmann W, Herrmann M. The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases. Nutrients. 2022 Mar 28;14(7):1412. doi: 10.3390/nu14071412. PMID: 35406025; PMCID: PMC9003430.

Reviewed By:

Yoshinori Abe

Yoshinori Abe, MD (Internal medicine)

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Shohei Harase

Shohei Harase, MD


Kameda Medical Center, Japan

Yu Shirai

Yu Shirai, MD


Yotsuya Yui Clinic, Japan

Yoshinori Abe

Yoshinori Abe, MD

Internal medicine

Co-founder of Ubie, Inc.

Rohini R

Rohini R, MD

Ear, nose, throat (ENT)

Bayshore Health Centre, India

Seiji Kanazawa

Seiji Kanazawa, MD, PHD

Obstetrics and gynecology (OBGYN)

National Center for Child Health and Development, Japan

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