Muscle Tenderness in Limbs
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Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Primary Care Physician)

Dr Patel graduated from the Zhejiang University School of Medicine. She worked in clinical research at the University of Illinois in Chicago and University of Nevada in Las Vegas focused on culturally adapted health interventions for preventive medicine in the community setting. Received her Master's of Science in Global Health (concentration in Health Policy) from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. Unnati went on to complete her family medicine residency in Chicago, Illinois at Norwegian American Hospital. | | She is currently working as a primary care physician in the city of Chicago and completing her Master's of Business Administration at the Northwestern University Kellogg School of Management and Fellowship in Leadership in Value-Based Care.

Yoshinori Abe, MD

Yoshinori Abe, MD (Internal medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

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Content updated on Jan 4, 2023

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  • My muscles hurt when my arms or legs are squeezed

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About the Symptom

This refers to a painful feeling in the muscle or limb when it is gripped tightly.

When to see a doctor

Seek professional care if you experience any of the following symptoms

  • Muscle tenderness in limbs

Possible causes

Generally, Muscle tenderness in limbs can be related to:

  • Fibromyalgia

    A condition causing widespread pain and muscle aches throughout the body that may come and go with certain identified triggers. The cause is not well understood.

  • Juvenile idiopathic arthritis (JIA)

    Juvenile idiopathic arthritis (JIA) is a type of arthritis that occurs in children under 16 years old. It's a chronic condition characterized by joint pain and swelling that can last for months or years. It affects one or more joints for at least 6 weeks. JIA occurs when the body's immune system attacks its own tissues The cause of JIA is unknown.

  • Eosinophilic Fasciitis

    The tissue under the skin and above the muscle is called fascia. In eosinophilic fasciitis, the fascia becomes red, swollen, and thick. The most commonly affected areas are the skin over the legs, neck, abdomen, and feet. The exact cause is unknown, but it might be due to nonspecific triggers causing an abnormal allergic or inflammatory reaction.

  • Relapsing Polychondritis
  • Multiple myeloma (MM)

Related serious diseases

Sometimes, Muscle tenderness in limbs may be related to these serious diseases:

  • Rhabdomyolysis

    Rhabdomyolysis is caused by the breakdown of muscle fibers, which release their contents into the blood, leading to electrolyte disturbances and kidney failure. If not treated, it can be potentially fatal. Causes include crush injuries to muscles, overexertion, alcohol misuse, and certain medications that can cause spontaneous muscle injury.

  • Venous embolism
  • Gas gangrene
  • Necrotizing Fasciitis
  • Heatstroke

Doctor's Diagnostic Questions

Your doctor may ask these questions to check for this symptom:

  • Do you feel pain in your arm and leg when they are grasped?

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Find Similar Symptoms

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Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Primary Care Physician)

Dr Patel graduated from the Zhejiang University School of Medicine. She worked in clinical research at the University of Illinois in Chicago and University of Nevada in Las Vegas focused on culturally adapted health interventions for preventive medicine in the community setting. Received her Master's of Science in Global Health (concentration in Health Policy) from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. Unnati went on to complete her family medicine residency in Chicago, Illinois at Norwegian American Hospital. | | She is currently working as a primary care physician in the city of Chicago and completing her Master's of Business Administration at the Northwestern University Kellogg School of Management and Fellowship in Leadership in Value-Based Care.

Yoshinori Abe, MD

Yoshinori Abe, MD (Internal medicine)

Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.

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