Antiphospholipid Syndrome Quiz
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Can't get pregnant
There are blisters
Difficulty conceiving
Causing a blister
Infertility
I have blisters on my chin
Difficulty becoming pregnant
Not seeing your symptoms? No worries!
What is Antiphospholipid Syndrome?
Antiphospholipid syndrome (APLS) is a multisystem autoimmune disorder that occurs when the immune system mistakenly produces antibodies that make the blood more likely to clot. As a result people with APLS are at increased risk of blood clots in the legs, kidneys, lungs, and brain.
Typical Symptoms of Antiphospholipid Syndrome
- History of deep vein thrombosis / blood clot in my leg veins
- Weakness or paralysis on one side of your body
- Difficulty getting pregnant
- Red skin with lace-like pattern
- Yellowish eyes or skin
- Blisters on the skin
- Blood in urine
- History of previous miscarriage or abortion
Diagnostic Questions for Antiphospholipid Syndrome
Your doctor may ask these questions to check for this disease:
- Have you ever had deep vein thrombosis (economy class syndrome)?
- Do you have weakness or paralysis on one side of your body?
- Are you struggling to conceive?
- Do you have red skin with a lace-like pattern?
- Have you noticed any yellowing of your eyes or skin?
Treatment of Antiphospholipid Syndrome
Medications to thin the blood and prevent clots are prescribed.
Reviewed By:
Kenji Taylor, MD, MSc (Family Medicine, Primary Care)
Dr. Taylor is a Japanese-African American physician who grew up and was educated in the United States but spent a considerable amount of time in Japan as a college student, working professional and now father of three. After graduating from Brown, he worked in finance first before attending medical school at Penn. He then completed a fellowship with the Centers for Disease Control before going on to specialize in Family and Community Medicine at the University of California, San Francisco (UCSF) where he was also a chief resident. After a faculty position at Stanford, he moved with his family to Japan where he continues to see families on a military base outside of Tokyo, teach Japanese residents and serve remotely as a medical director for Roots Community Health Center. He also enjoys editing and writing podcast summaries for Hippo Education.
Kaito Nakamura, MD (Rheumatology)
Dr. Nakamura is a rheumatologist who has practiced in the Ota Nishinouchi Hospital attached to Ota General Hospital, National Health Insurance Matsudo City Hospital, Chiba University Hospital, and the National Health Insurance Asahi Central Hospital.
Content updated on Mar 31, 2024
Following the Medical Content Editorial Policy
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Link to full study:
https://www.medrxiv.org/content/10.1101/2024.08.29.24312810v1References
Sammaritano LR. Antiphospholipid syndrome. Best Pract Res Clin Rheumatol. 2020 Feb;34(1):101463. doi: 10.1016/j.berh.2019.101463. Epub 2019 Dec 19. PMID: 31866276.
https://www.sciencedirect.com/science/article/abs/pii/S1521694219301597?via%3DihubPetri M. Antiphospholipid syndrome. Transl Res. 2020 Nov;225:70-81. doi: 10.1016/j.trsl.2020.04.006. Epub 2020 May 12. PMID: 32413497; PMCID: PMC7487027.
https://www.translationalres.com/article/S1931-5244(20)30069-4/fulltextGarcia D, Erkan D. Diagnosis and Management of the Antiphospholipid Syndrome. N Engl J Med. 2018 May 24;378(21):2010-2021. doi: 10.1056/NEJMra1705454. PMID: 29791828.
https://www.nejm.org/doi/10.1056/NEJMra1705454Cervera R. Antiphospholipid syndrome. Thromb Res. 2017 Mar;151 Suppl 1:S43-S47. doi: 10.1016/S0049-3848(17)30066-X. PMID: 28262233.
https://www.thrombosisresearch.com/article/S0049-3848(17)30066-X/pdf