Hyperprolactinemia Quiz

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Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Family Medicine)

Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.

Hidetaka Hamasaki, MD

Hidetaka Hamasaki, MD (Endocrinology)

Dr. Hamasaki graduated from the Hiroshima University School of Medicine and the Graduate School of Medicine, Jichi Medical University. He completed his residency at the Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine Hospital and the Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine. He has served in the National Center for Global Health and Medicine Hospital and Kohnodai Hospital and joined Hamasaki Clinic in April 2017. Dr. Hamasaki specializes in diabetes and treats a wide range of internal medicine and endocrine disorders.

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Content updated on Mar 31, 2024

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How Ubie Can Help You

With an easy 3-min questionnaire , Ubie's AI-powered system will generate a free report on possible causes.

Questions are customized to your situation and symptoms, including the following personal information:

  • Biological Sex - helps us provide relevant suggestions for male vs. female conditions.

  • Age - adjusts our guidance based on any age-related health factors.

  • History - considers past illnesses, surgeries, family history, and lifestyle choices.

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People with similar symptoms also use Ubie's symptom checker to find possible causes

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  • Swollen male breast

  • Enlarged breasts in men

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  • Galactorrhea

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  • Before the hair loss, the scalp was itchy

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What is Hyperprolactinemia?

Excessively high prolactin (hormone that releases milk) levels in the blood. Causes include medications and brain tumors.

Typical Symptoms of Hyperprolactinemia

  • Enlarged male breast tissue

  • Inappropriate milk production e.g. not pregnant or with recent childbirth, or as a male

  • Headache

  • Hair loss

  • History of underactive thyroid / low thyroid levels

  • Nipple rash, redness, discharge, pain or itch

  • On psychiatric medications or sleeping pills

  • Difficulty achieving or maintaining an erection

Doctor's Diagnostic Questionson Hyperprolactinemia

Your doctor may ask these questions to check for this disease:

  • Have you noticed an unusual increase in your breast size?

  • Are you producing breast milk without being pregnant or giving birth, or if you are a man?

  • Do you have headaches or a heavy feeling in your head?

  • Are you experiencing increased hair loss?

  • Have you ever been diagnosed with an underactive thyroid (hypothyroidism)?

Treatmentof Hyperprolactinemia

Treatment focuses on lowering prolactin levels back to normal. This is typically done with medications. In some cases, surgery or radiation may be required to remove a tumor.

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References

  • Melmed S, Casanueva FF, Hoffman AR, Kleinberg DL, Montori VM, Schlechte JA, Wass JA; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Feb;96(2):273-88. doi: 10.1210/jc.2010-1692. PMID: 21296991.

    https://academic.oup.com/jcem/article/96/2/273/2709487

  • Capozzi A, Scambia G, Pontecorvi A, Lello S. Hyperprolactinemia: pathophysiology and therapeutic approach. Gynecol Endocrinol. 2015 Jul;31(7):506-10. doi: 10.3109/09513590.2015.1017810. Epub 2015 Jul 6. PMID: 26291795.

    https://www.tandfonline.com/doi/full/10.3109/09513590.2015.1017810

  • Vilar L, Vilar CF, Lyra R, Freitas MDC. Pitfalls in the Diagnostic Evaluation of Hyperprolactinemia. Neuroendocrinology. 2019;109(1):7-19. doi: 10.1159/000499694. Epub 2019 Mar 20. PMID: 30889571.

    https://www.karger.com/Article/FullText/499694

  • Chahal J, Schlechte J. Hyperprolactinemia. Pituitary. 2008;11(2):141-6. doi: 10.1007/s11102-008-0107-5. PMID: 18404389.

    https://link.springer.com/article/10.1007/s11102-008-0107-5

  • Matalliotakis M, Koliarakis I, Matalliotaki C, Trivli A, Hatzidaki E. Clinical manifestations, evaluation and management of hyperprolactinemia in adolescent and young girls: a brief review. Acta Biomed. 2019 Jan 23;90(1):149-157. doi: 10.23750/abm.v90i1.8142. PMID: 30889169; PMCID: PMC6502148.

    https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/8142

  • Hyperprolactinemia - Johns Hopkins Medicine

    https://www.hopkinsmedicine.org/health/conditions-and-diseases/hyperprolactinemia#:~:text=Hyperprolactinemia%20is%20marked%20by%20abnormally,controls%20production%20of%20this%20hormone.

User Testimonials

Reviewed By:

Unnati Patel, MD, MSc

Unnati Patel, MD, MSc (Family Medicine)

Dr.Patel serves as Center Medical Director and a Primary Care Physician at Oak Street Health in Arizona. She graduated from the Zhejiang University School of Medicine prior to working in clinical research focused on preventive medicine at the University of Illinois and the University of Nevada. Dr. Patel earned her MSc in Global Health from Georgetown University, during which she worked with the WHO in Sierra Leone and Save the Children in Washington, D.C. She went on to complete her Family Medicine residency in Chicago at Norwegian American Hospital before completing a fellowship in Leadership in Value-based Care in conjunction with the Northwestern University Kellogg School of Management, where she earned her MBA. Dr. Patel’s interests include health tech and teaching medical students and she currently serves as Clinical Associate Professor at the University of Arizona School of Medicine.

Hidetaka Hamasaki, MD

Hidetaka Hamasaki, MD (Endocrinology)

Dr. Hamasaki graduated from the Hiroshima University School of Medicine and the Graduate School of Medicine, Jichi Medical University. He completed his residency at the Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine Hospital and the Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine. He has served in the National Center for Global Health and Medicine Hospital and Kohnodai Hospital and joined Hamasaki Clinic in April 2017. Dr. Hamasaki specializes in diabetes and treats a wide range of internal medicine and endocrine disorders.

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