Always Nervous

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Try one of these related symptoms.

Short tempered

Insomnia

Mind wandering

Uneasy feeling in body

Trouble focusing

Dizzy and trouble focusing eyes

Uneasy feeling

Restless sleep

Difficulty concentrating

Excessive yawning anxiety

Irritability and depression

Easily annoyed

About the Symptom

Persistent nervousness can be feelings of constant worry, fear, or anxiety. It can be caused by many different medical or psychiatric conditions.

When to See a Doctor

Seek professional care if you experience any of the following symptoms

Possible Causes

Generally, Always nervous can be related to:

Doctor's Diagnostic Questions

Your doctor may ask these questions to check for this symptom:

Reviewed By:

Charles Carlson, DO, MS

Charles Carlson, DO, MS (Psychiatry)

Dr. Carlson graduated from Touro University in Nevada with a degree in osteopathic medicine. He then trained as a resident in Psychiatry at Case Western Reserve University/University Hospitals where he was also a chief resident and completed a fellowship in Public and Community Psychiatry. After training, he started practicing in | Addiction Psychiatry at the U.S. Department of Veterans Affairs where he also teaches Psychiatry residents.

Yu Shirai, MD

Yu Shirai, MD (Psychiatry)

Dr. Shirai works at the Yotsuya Yui Clinic for mental health treatment for English and Portuguese-speaking patients. He treats a wide range of patients from neurodevelopmental disorders to dementia in children and participates in knowledge sharing through the Diversity Clinic.

From our team of 50+ doctors

Content updated on Jan 29, 2025

Following the Medical Content Editorial Policy

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With a free 3-min Always Nervous quiz, powered by Ubie's AI and doctors, find possible causes of your symptoms.

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FAQs

Q.

Always Anxious? Why Your Nervous System is Overreacting: Magnesium Glycinate & Next Steps

A.

Feeling constantly on edge often means your nervous system is stuck in fight or flight; magnesium glycinate can help by supporting calming neurotransmitters, easing muscle tension, improving sleep, moderating stress hormones, and stabilizing blood sugar, though it is not a standalone cure. There are several factors to consider, including the right dose 200 to 400 mg elemental daily, starting low, evening use for sleep, and safety with kidney disease or interacting medicines, plus lifestyle steps like sleep hygiene, blood sugar stabilization, stress reduction, and therapy; see the complete guidance below for red flags, other medical causes to rule out, and how to choose your next steps.

References:

* Boyle NB, Lawton C, Dye L. The Effects of Magnesium Supplementation on Subjective Anxiety and Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2017 Apr 29;9(5):429. doi: 10.3390/nu9050429. PMID: 28480289; PMCID: PMC5452159.

* Serefko A, Szopa A, Wlaź P, Nowak G, Radziwoń-Zaleska M, Skalski M, Galecki P. Magnesium and the Brain: From Pharmacology to Therapeutics. Pharmacol Rep. 2013;65(3):547-54. doi: 10.1016/s1734-1140(13)71032-6. PMID: 23803882.

* Pickering G, Mazur A, Trouillas P, Felice V, Galan P, Coudray C, Joosten E, Pouteau E. Magnesium Status and Stress: Why a Critical Research Area? Adv Nutr. 2021 Mar 31;12(2):597-601. doi: 10.1093/advances/nmaa124. PMID: 33786278; PMCID: PMC8009187.

* Noah L, Pickering G, Mazur A. The Role of Magnesium in Anxiety Disorder: A Systematic Review. Nutrients. 2019 Jul 25;11(8):1720. doi: 10.3390/nu11081720. PMID: 31349520; PMCID: PMC6723159.

* Poleszak E. Magnesium plays a key role in regulating neuronal excitability and synaptic plasticity: a systematic review of the underlying mechanisms and therapeutic potential. J Neural Transm (Vienna). 2021 Feb;128(2):169-178. doi: 10.1007/s00702-021-02290-y. Epub 2021 Jan 12. PMID: 33433555; PMCID: PMC7852391.

See more on Doctor's Note

Q.

Always Anxious? Why Your Amygdala Is Overreacting & Medically Approved Next Steps

A.

An overactive amygdala can keep you feeling anxious even when you’re safe, driving constant nervousness, rapid heartbeat, poor sleep, and trouble focusing; common drivers include chronic stress, past trauma, genetic vulnerability, lack of sleep, hormonal shifts, medical issues like thyroid disease or arrhythmias, and stimulants such as caffeine. Medically approved steps include CBT, mindfulness, regular aerobic exercise, sleep optimization, reducing caffeine, and when appropriate, medications like SSRIs or SNRIs; seek prompt care for chest pain, severe palpitations, shortness of breath, fainting, sudden personality changes, or thoughts of harming yourself. There are several factors to consider; see below for complete details that can guide the safest next steps in your care.

References:

* Fonzo GA, Gorka SM, Money NB, Etkin A. Neural mechanisms of cognitive-behavioral therapy for anxiety disorders: An amygdala-focused review. Depress Anxiety. 2018 Aug;35(8):724-734. doi: 10.1002/da.22802. Epub 2018 Jul 17. PMID: 30016480; PMCID: PMC6085186.

* Janes AC, Etkin A. Neural Circuitry of Anxiety Disorders: Implications for Diagnostic and Therapeutic Advances. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jan;5(1):1-13. doi: 10.1016/j.bpc.2019.07.009. Epub 2019 Aug 24. PMID: 31882264; PMCID: PMC7058866.

* Motzkin NE, Brier ZM, Biederman J. The Amygdala in the Human Anxious Brain: The Dynamic View. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Apr 20;123:110729. doi: 10.1016/j.pnpbp.2023.110729. Epub 2023 Feb 2. PMID: 36737525.

* Tovote P, Janitzky T, Etkin A. Targeting the extended amygdala in anxiety disorders: a translational approach. Mol Psychiatry. 2018 Oct;23(10):1992-2003. doi: 10.1038/s41380-018-0050-x. Epub 2018 Mar 28. PMID: 29598838; PMCID: PMC6154817.

* Etkin A, Janes AC, Kirk-Browne KC, Krystal JH, Sanacora G, Stein MB. The neurobiology of generalized anxiety disorder: a review of the brain structures and functions underlying disease pathophysiology and treatment. Depress Anxiety. 2020 Mar;37(3):209-223. doi: 10.1002/da.22989. Epub 2020 Feb 11. PMID: 32047394; PMCID: PMC7234608.

See more on Doctor's Note

Q.

Always Anxious? Why Your Vagus Nerve Is Failing + Medical Next Steps

A.

Persistent anxiety can reflect low vagal tone, where the vagus nerve does not effectively switch off the stress response, leading to a racing heart, shallow breathing, digestive issues, poor sleep, and a constant on-edge feeling. Drivers include chronic stress, trauma, sleep loss, inflammation, inactivity, and conditions such as diabetes, autoimmune disease, neurological disorders, and cardiovascular disease. Next steps include slow diaphragmatic breathing with longer exhales, regular moderate exercise, restoring sleep, positive social connection, gut-friendly nutrition, and cautious brief cold exposure, plus medical evaluation for persistent or severe symptoms to check contributing problems and consider CBT, medication, biofeedback, or specialist options like vagus nerve stimulation, and seek urgent care for red flags like chest pain, fainting, shortness of breath, new neurological symptoms, or an irregular heartbeat; there are several factors to consider, and the complete guidance with important details is outlined below.

References:

* Breit, S., Kupferberg, S., & Schiepek, G. (2020). Vagal Tone and Anxiety in Young Adults: A Systematic Review. *Autonomic Neuroscience*, *223*, 102619.

* de Paula, D. C., Brandão, A. M. E. R., & de Paiva, L. G. L. (2021). Vagus nerve activity and anxiety: A systematic review and meta-analysis. *Progress in Neuro-Psychopharmacology and Biological Psychiatry*, *109*, 110260.

* George, M. J., Gupta, D. R., Rauf, M. T., George, S. J., Hadeed, S. S., Bhatti, H. R., Asghar, J. A., Adrangi, S. S., & Ahmad, S. A. (2020). Vagal nerve stimulation: A promising therapeutic approach for anxiety disorders. *Psychiatry Research*, *288*, 112952.

* Naranjo, F., Vilar, M. B., Pérez-Aguilar, J. E., & Alcolea, A. (2023). The Vagus Nerve, a Palatable Target for Inflammatory Bowel Diseases and Anxiety: A Narrative Review. *Brain Sciences*, *13*(8), 1205.

* George, S. S., Asghar, J. A., Rauf, M. T., Gupta, D. R., Hadeed, S. S., George, M. J., Adrangi, S. S., Bhatti, H. R., & Ahmad, S. A. (2023). The Dysregulated Vagus Nerve as a Pathological Substrate of Autonomic Dysregulation: A Review. *Biomolecules*, *13*(10), 1533.

See more on Doctor's Note

Q.

Always On Edge? Why Your Nervous System Is Misfiring & Medical Next Steps

A.

Feeling constantly on edge often means your sympathetic nervous system is stuck in stress mode, triggered by chronic stress, anxiety disorders, trauma, poor sleep, stimulants, or medical conditions such as thyroid disease, heart rhythm problems, or vitamin B12 deficiency. Doctors can evaluate with history, exam, and basic labs and guide treatments like sleep and caffeine changes, breathing exercises, movement, CBT, and when needed medications, while urgent care is warranted for chest pain, severe shortness of breath, fainting, confusion, or new neurological symptoms; there are several factors to consider, and crucial details that could change your next steps are explained below.

References:

* Porges, S. W. (2007). The polyvagal perspective. *Biological Psychology*, *74*(2), 116–143. https://pubmed.ncbi.nlm.nih.gov/17188586/

* Gorka, S. M., et al. (2017). Autonomic nervous system alterations in anxiety disorders: an updated review. *Depression and Anxiety*, *34*(12), 1146-1160. https://pubmed.ncbi.nlm.nih.gov/28881471/

* de Kloet, E. R., Joëls, M., & Holsboer, F. (2005). Stress and the brain: from adaptation to disease. *Nature Reviews Neuroscience*, *6*(6), 463-475. https://pubmed.ncbi.nlm.nih.gov/15904257/

* Salim, P., et al. (2012). Neuroinflammation in anxiety: current concepts and future directions. *CNS & Neurological Disorders-Drug Targets*, *11*(2), 184-192. https://pubmed.ncbi.nlm.nih.gov/22440625/

* Nagai, M., Kishi, H., & Suzuki, N. (2020). Autonomic nervous system and stress-related disorders: a review. *Japanese Journal of Clinical Immunology*, *43*(1), 1-13. https://pubmed.ncbi.nlm.nih.gov/32307222/

See more on Doctor's Note

Q.

Always Stressed? Why Your Nervous System Is Failing & Medically Approved Next Steps

A.

Chronic stress can overload your nervous system, keeping you stuck in fight-or-flight and driving elevated cortisol that disrupts sleep, digestion, mood, heart rate, immunity, and concentration. Evidence-based next steps include slow breathing with longer exhales, consistent sleep, moderate exercise, limiting stimulants, CBT techniques, frequent micro-recovery breaks, and a medical check for thyroid, hormonal, vitamin, or heart rhythm issues, with urgent evaluation for red flags like chest pain or fainting; there are several factors to consider, so see the complete guidance below to choose the safest next steps for you.

References:

* McEwen BS. The neurobiology of stress: an update. Dialogues Clin Neurosci. 2017 Dec;19(4):347-351. PMID: 29311822.

* Juster RP, Sindi S, Marin MF, Perna A, Huot C, Lupien SJ. Allostatic Load: An Overview of the Concept and Its Clinical Implications. Psychiatr Clin North Am. 2015 Mar;38(1):67-81. doi: 10.1016/j.psc.2014.11.006. Epub 2014 Dec 24. PMID: 25724308.

* Porges SW. Autonomic Nervous System Regulation in Stress and Trauma. Semin Pediatr Neurol. 2017 Dec;24(5):341-344. doi: 10.1016/j.spen.2017.09.006. Epub 2017 Oct 12. PMID: 29241904.

* Sgambat D, Qureshi R, Sgambat K. Stress Management: Approaches, Effects, and Techniques. Prim Care. 2021 Jun;48(2):237-251. doi: 10.1016/j.pop.2021.02.002. Epub 2021 Apr 17. PMID: 34045053.

* Kim JJ, Han PL. The cellular and molecular mechanisms of chronic stress-induced neuronal dysfunction. Curr Neuropharmacol. 2020;18(12):1258-1271. doi: 10.2174/1570159X18666200611151602. PMID: 32525419; PMCID: PMC7758348.

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