Bump on Lip
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Bump on lip
White bump on lip
Tiny bumps on lips
Painless bump on upper lip
Bump on inside of lip
Red bump on lip
Red spot on lip no bump
Swollen bump on lip out of nowhere
Hard bump on lip
Pea sized lump in upper lip
Big bump on lip
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About the Symptom
An isolated bump on the lip is most commonly due to a blocked oil gland, a wart, or a blood vessel. Multiple bumps on lips can be caused by acne, cold sores, other infections and a benign overgrowth of oil glands.
Possible Causes
Generally, Bump on lip can be related to:
- Cheilitis Granulomatosa (Granulomatous Cheilitis)
Cheilitis granulomatosa is a rare condition, characterized by painless but persistent inflammatory swelling of the lip. The cause is unknown, but could be due to factors like foreign body reactions, infections, and other inflammatory conditions.
Doctor's Diagnostic Questions
Your doctor may ask these questions to check for this symptom:
- Do you have bumps or lumps on your lips?
- How long have you had a rash on your lips?
Reviewed By:
Sarita Nori, MD (Dermatology)
Dr. Sarita Nori was drawn to dermatology because of the intersection of science and medicine that is at the heart of dermatology. She feels this is what really allows her to help her patients. “There is a lot of problem-solving in dermatology and I like that,” she explains. “It’s also a profession where you can help people quickly and really make a difference in their lives.” | Some of the typical skin problems that Dr. Nori treats include skin cancers, psoriasis, acne, eczema, rashes, and contact dermatitis. Dr Nori believes in using all possible avenues of treatment, such as biologics, especially in patients with chronic diseases such as eczema and psoriasis. “These medications can work superbly, and they are really life-changing for many patients.” | Dr. Nori feels it’s important for patients to have a good understanding of the disease or condition that is affecting them. “I like to educate my patients on their problem and have them really understand it so they can take the best course of action. Patients always do better when they understand their skin condition, and how to treat it.”
Yoshinori Abe, MD (Internal Medicine)
Dr. Abe graduated from The University of Tokyo School of Medicine in 2015. He completed his residency at the Tokyo Metropolitan Health and Longevity Medical Center. He co-founded Ubie, Inc. in May 2017, where he currently serves as CEO & product owner at Ubie. Since December 2019, he has been a member of the Special Committee for Activation of Research in Emergency AI of the Japanese Association for Acute Medicine. | | Dr. Abe has been elected in the 2020 Forbes 30 Under 30 Asia Healthcare & Science category.
Content updated on Feb 6, 2025
Following the Medical Content Editorial Policy
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FAQs
Q.
Could HPV Cause White Spots on My Lips?
A.
HPV can cause certain wart-like lesions in the mouth, but it is not usually the cause of plain white spots on the lips. Other conditions may be responsible for white spots, so it’s important to have any unusual changes evaluated.
References:
Syrjänen S. Oral manifestations of human papillomavirus infections. Eur J Oral Sci. 2018 Oct;126 Suppl 1(Suppl Suppl 1):49-66. doi: 10.1111/eos.12538. PMID: 30178562; PMCID: PMC6174935.
Jamieson LM, Antonsson A, Garvey G, et al. Prevalence of Oral Human Papillomavirus Infection Among Australian Indigenous Adults. _JAMA Netw Open._ 2020;3(6):e204951. doi:10.1001/jamanetworkopen.2020.4951
Haghshenas MR, Moosazadeh M, Taghiloo S, Sattari S, Valadan R, Mousavi T. Association between Human Papillomavirus and Oral Cancer in Iranian Clinical Samples: A Meta-Analysis Review. Iran J Public Health. 2022 Dec;51(12):2688-2696. doi: 10.18502/ijph.v51i12.11459. PMID: 36742241; PMCID: PMC9874207.
Q.
What Could a Bump on My Lip Be If It's Not a Cold Sore?
A.
There are several harmless conditions that can cause a bump on your lip. It might be a mucocele, fibroma, or a small blood vessel growth, and each one is usually not dangerous.
References:
More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol. 2014 Sep;18(Suppl 1):S72-7. doi: 10.4103/0973-029X.141370. PMID: 25364184; PMCID: PMC4211243.
Fernandez-Flores A, Colmenero I. Campbell de Morgan Spots (Cherry Angiomas) Show Endothelial Proliferation. Am J Dermatopathol. 2018 Dec;40(12):894-898. doi: 10.1097/DAD.0000000000001216. PMID: 30024413.
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA. Benign oral mucosal lesions: Clinical and pathological findings. J Am Acad Dermatol. 2019 Jul;81(1):43-56. doi: 10.1016/j.jaad.2018.09.061. Epub 2018 Nov 14. PMID: 30447312.
Q.
Could a Clear Bump on the Inside of My Lip Be an STD?
A.
It is unlikely that a clear bump on the inside of your lip is an STD. More often, such a bump can be a harmless condition like a mucocele.
References:
Bruce AJ, Rogers RS 3rd. Oral manifestations of sexually transmitted diseases. Clin Dermatol. 2004 Nov-Dec;22(6):520-7. doi: 10.1016/j.clindermatol.2004.07.005. PMID: 15596324.
Kreimer AR, Bhatia RK, Messeguer AL, González P, Herrero R, Giuliano AR. Oral human papillomavirus in healthy individuals: a systematic review of the literature. Sex Transm Dis. 2010 Jun;37(6):386-91. doi: 10.1097/OLQ.0b013e3181c94a3b. PMID: 20081557.
Kim SM. Human papilloma virus in oral cancer. J Korean Assoc Oral Maxillofac Surg. 2016 Dec;42(6):327-336. doi: 10.5125/jkaoms.2016.42.6.327. Epub 2016 Dec 27. PMID: 28053902; PMCID: PMC5206237.
Q.
How Can I Tell If a Bump on My Lip Is Herpes?
A.
Herpes on the lip usually starts with a tingling feeling and appears as small, painful clusters of blisters that can break open and form sores.
References:
Birt D, Main J. Oral manifestations of herpes simplex virus infections. Laryngoscope. 1977 Jun;87(6):872-8. doi: 10.1288/00005537-197706000-00004. PMID: 865205.
Corey L. First-episode, recurrent, and asymptomatic herpes simplex infections. J Am Acad Dermatol. 1988 Jan;18(1 Pt 2):169-72. doi: 10.1016/s0190-9622(88)70020-1. PMID: 3276742.
Crimi S, Fiorillo L, Bianchi A, D'Amico C, Amoroso G, Gorassini F, Mastroieni R, Marino S, Scoglio C, Catalano F, Campagna P, Bocchieri S, De Stefano R, Fiorillo MT, Cicciù M. Herpes Virus, Oral Clinical Signs and QoL: Systematic Review of Recent Data. Viruses. 2019 May 21;11(5):463. doi: 10.3390/v11050463. PMID: 31117264; PMCID: PMC6563194.
Q.
What Might Cause a White Bump on the Inside of My Lip?
A.
A white bump on the inside of your lip may be caused by mild injury, irritation, or a small sore like a canker sore. These bumps are usually not serious but should be watched if they change or last a long time.
References:
Mortazavi H, Safi Y, Baharvand M, Jafari S, Anbari F, Rahmani S. Oral White Lesions: An Updated Clinical Diagnostic Decision Tree. Dent J (Basel). 2019 Feb 7;7(1):15. doi: 10.3390/dj7010015. PMID: 30736423; PMCID: PMC6473409.
Ferreli C, Giannetti L, Robustelli Test E, Atzori L, Rongioletti F. Linear white lesion in the oral mucosa. JAAD Case Rep. 2019 Aug 5;5(8):694-696. doi: 10.1016/j.jdcr.2019.05.009. PMID: 31440559; PMCID: PMC6698443.
InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Canker sores (mouth ulcers) [Updated 2022 Oct 17].Available from: https://www.ncbi.nlm.nih.gov/books/NBK546250/
Q.
What Could Cause Tiny Bumps on My Lips to Feel Like Sandpaper?
A.
Tiny, rough bumps on the lips can be a sign of cheilitis or similar skin changes, which may be caused by irritation, sun exposure, or habits like excessive lip licking or picking.
References:
Bouwes Bavinck JN, Euvrard S, Naldi L, Nindl I, Proby CM, Neale R, Abeni D, Tessari GP, Feltkamp MC, Claudy A, Stockfleth E, Harwood CA; EPI-HPV-UV-CA group. Keratotic skin lesions and other risk factors are associated with skin cancer in organ-transplant recipients: a case-control study in The Netherlands, United Kingdom, Germany, France, and Italy. J Invest Dermatol. 2007 Jul;127(7):1647-56. doi: 10.1038/sj.jid.5700776. Epub 2007 Mar 22. PMID: 17380113; PMCID: PMC2478722.
Bhutta BS, Hafsi W. Cheilitis. [Updated 2023 Aug 17]. In: StatPearls [Internet].
Santos LR, Dick TN, Candreva MS, Marques LC, Milagres A, Rozza-de-Menezes RE, Junior AS, Cunha KS, Conde DC. Challenging of treating patients with exfolliative cheilittis: Report of two cases. J Clin Exp Dent. 2023 May 1;15(5):e431-e436. doi: 10.4317/jced.60326. PMID: 37214748; PMCID: PMC10198695.
Charifa A, Badri T, Harris BW. Lichen Simplex Chronicus. [Updated 2023 Aug 7]. In: StatPearls [Internet].
Q.
Are Bumps on the Inside of My Lip Normal?
A.
Sometimes small bumps on the inside of your lip are normal, like minor canker sores or effects from slight irritation. However, if they are painful, persist for a long time, or change in appearance, you should have them checked by a healthcare provider.
References:
InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Canker sores (mouth ulcers) [Updated 2022 Oct 17].Available from: https://www.ncbi.nlm.nih.gov/books/NBK546250/
Gual-Vaqués P, Jané-Salas E, Egido-Moreno S, Ayuso-Montero R, Marí-Roig A, López-López J. Inflammatory papillary hyperplasia: A systematic review. Med Oral Patol Oral Cir Bucal. 2017 Jan 1;22(1):e36-e42. doi: 10.4317/medoral.21405. PMID: 27918740; PMCID: PMC5217495.
Mohammed F, Fairozekhan AT. Oral Leukoplakia. [Updated 2023 Jul 17]. In: StatPearls [Internet].
Arnold DL, Krishnamurthy K. Lichen Planus. [Updated 2024 Oct 29]. In: StatPearls [Internet].
Q.
Why Do I Have a Big Bump on My Lip?
A.
A big bump on your lip could be a mucocele (salivary gland cyst), a benign tumor, or another type of oral lesion.
References:
More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol. 2014 Sep;18(Suppl 1):S72-7. doi: 10.4103/0973-029X.141370. PMID: 25364184; PMCID: PMC4211243.
Vasconcelos ACU, Loyola AM, Gomes APN, de Araújo VC, Tarquínio SBC, Silveira FM, de Aguiar MCF. A symptomatic swelling of the upper lip. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Feb;125(2):107-111. doi: 10.1016/j.oooo.2017.10.012. Epub 2017 Nov 17. PMID: 29248422.
Bhandarkar GP, Shetty KV. Differential diagnoses of elevated lesions of the upper lip: An overview. J Cancer Res Ther. 2017 Apr-Jun;13(2):170-174. doi: 10.4103/0973-1482.204890. PMID: 28643729.
Kannan N, Ramalingam K, Kizhakkoottu S, Ramani P. The Diagnostic Considerations and Clinical Management of Lower Lip Swellings in Adolescents: A Narrative Review. Cureus. 2024 Oct 17;16(10):e71707.
Q.
What Could a Red Spot on My Lip Without a Blister Indicate?
A.
A red spot on your lip without a blister can sometimes be a sign of sun damage known as actinic cheilitis, which is a condition that needs monitoring. It might also be a harmless blood vessel or inflammation, but any changes in this spot should be checked by a doctor.
References:
Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK551553/
https://www.ncbi.nlm.nih.gov/books/NBK551553/
McNamara KK, Kalmar JR. Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities. Head Neck Pathol. 2019 Mar;13(1):4-15. doi: 10.1007/s12105-019-01002-8. Epub 2019 Jan 29. PMID: 30693460; PMCID: PMC6405795.
Drago F, Ciccarese G, Merlo G, Trave I, Javor S, Rebora A, Parodi A. Oral and cutaneous manifestations of viral and bacterial infections: Not only COVID-19 disease. Clin Dermatol. 2021 May-Jun;39(3):384-404. doi: 10.1016/j.clindermatol.2021.01.021. Epub 2021 Feb 1. PMID: 34517997; PMCID: PMC7849469.
Q.
What Could a Painless Bump on My Lip Mean?
A.
A painless bump on your lip could be a harmless growth such as a mucocele. Evaluation by a doctor can help decide if treatment is needed.
References:
Gudi SS, Sikkerimath BC, Puranik RS, Kasbe SS. Swelling on lower lip…not always a mucocele !!! Ann Maxillofac Surg. 2013 Jan;3(1):98-9. doi: 10.4103/2231-0746.110080. PMID: 23662271; PMCID: PMC3645623.
Almutairi, A., Alaglan, A., Alenezi, M. _et al._ Nasolabial cyst: case report and review of management options. _BMC Surg_ 20, 10 (2020). https://doi.org/10.1186/s12893-020-0677-3
Kannan N, Ramalingam K, Kizhakkoottu S, Ramani P. The Diagnostic Considerations and Clinical Management of Lower Lip Swellings in Adolescents: A Narrative Review. Cureus. 2024 Oct 17;16(10):e71707. doi: 10.7759/cureus.71707. PMID: 39553086; PMCID: PMC11568828.
Q.
What Could a Small, Painless Bump on My Lip Indicate?
A.
A small, painless bump on your lip can sometimes be a harmless growth, like a vascular lesion, fibrous histiocytoma, or even a schwannoma. However, proper evaluation by a healthcare provider is needed for a clear diagnosis.
References:
Tobouti PL, Olegário I, de Sousa SC. Benign vascular lesions of the lips: Diagnostic approach. J Cutan Pathol. 2017 May;44(5):451-455. doi: 10.1111/cup.12911. Epub 2017 Feb 16. PMID: 28111788.
Maulana R, Pahlevi MR, Rosanto YB, Sejati BP, Hasan CY. A rare case of upper lip schwannoma: A case report with analysis of the histological, immunohistochemical and pathogenesis aspects. Int J Surg Case Rep. 2024 May;118:109445. doi: 10.1016/j.ijscr.2024.109445. Epub 2024 Feb 27. PMID: 38615463; PMCID: PMC11021950.
Migliario M, Rimondini L, Valente G. Benign fibrous histiocytoma of the lower lip. J Craniofac Surg. 2010 Nov;21(6):2024-6. doi: 10.1097/SCS.0b013e3181f537e0. PMID: 21119493.
Q.
What Might a White Bump on My Lip Be?
A.
A white bump on your lip is usually a benign condition. Most commonly it is related to a mucocele but there are other less common causes.
References:
Bansal S, Shaikh S, Desai RS, Ahmad I, Puri P, Prasad P, Shirsat P, Gundre D. Spectrum of Lip Lesions in a Tertiary Care Hospital: An Epidemiological Study of 3009 Indian Patients. Indian Dermatol Online J. 2017 Mar-Apr;8(2):115-119. doi: 10.4103/2229-5178.202280. PMID: 28405551; PMCID: PMC5372431.
Chaitanya P, Praveen D, Reddy M. Mucocele on Lower Lip: A Case Series. Indian Dermatol Online J. 2017 May-Jun;8(3):205-207. doi: 10.4103/idoj.IDOJ_151_16. PMID: 28584760; PMCID: PMC5447343.
McKinney R, Olmo H, McGovern B. Benign Chronic White Lesions of the Oral Mucosa. [Updated 2024 Jan 11]. In: StatPearls [Internet].
Q.
How Can I Get Rid of a Bump Inside My Lip?
A.
A bump inside the lip is most often a mucocele, which is a harmless pocket of saliva. A doctor or dentist can help you choose among treatment options.
References:
Shirbhate U, Bajaj P, Patil M, Dare S. Mucous Extravasation Cyst Associated With the Lower Lip and Its Management: A Case Report. Cureus. 2023 Oct 5;15(10):e46557. doi: 10.7759/cureus.46557. PMID: 37933354; PMCID: PMC10625657.
Gaikwad TV, Maini AP, Das S, Lokhande S, Patil SK, Sarma A. Nonsurgical Management of Oral Mucocele Occurring on a Rare Site. Contemp Clin Dent. 2022 Oct-Dec;13(4):389-391. doi: 10.4103/ccd.ccd_531_21. Epub 2022 Nov 11. PMID: 36686989; PMCID: PMC9855259.
Nallasivam KU, Sudha BR. Oral mucocele: Review of literature and a case report. J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S731-3. doi: 10.4103/0975-7406.163516. PMID: 26538955; PMCID: PMC4606697.
Q.
What Might a Painful Pea-Sized Lump in My Upper Lip Be?
A.
A painful pea-sized lump in your upper lip could be a blocked salivary gland, a type of benign tumor, or another condition.
References:
Suh DW, Lee EJ, Lew BL, Sim WY. Minor salivary gland sialolithiasis of the upper lip. Ann Dermatol. 2013 Nov;25(4):502-4. doi: 10.5021/ad.2013.25.4.502. Epub 2013 Nov 30. PMID: 24371404; PMCID: PMC3870225.
Hamilton AR, Paton A, Downie JJ. Glomangioma: rare case of a painful lump in the upper lip. Br J Oral Maxillofac Surg. 2019 Oct;57(8):788-790. doi: 10.1016/j.bjoms.2019.07.005. Epub 2019 Jul 23. PMID: 31345579.
Perić B, Vidaković B, Grgić N, Manojlović S, Čavka H. ANGIOMYOMA OF THE UPPER LIP - CASE REPORT AND REVIEW OF THE LITERATURE. Acta Clin Croat. 2019 Mar;58(1):183-186. doi: 10.20471/acc.2019.58.01.24. PMID: 31363342; PMCID: PMC6629197.
Bhandarkar GP, Shetty KV. Differential diagnoses of elevated lesions of the upper lip: An overview. J Cancer Res Ther. 2017 Apr-Jun;13(2):170-174. doi: 10.4103/0973-1482.204890. PMID: 28643729.
Q.
What Could Cause a Swollen Bump to Appear on My Lip Suddenly?
A.
A sudden swollen bump on your lip might be caused by a minor injury, an allergic reaction, or an infection. It’s important to watch it closely and seek advice if it doesn’t improve.
References:
Kannan N, Ramalingam K, Kizhakkoottu S, Ramani P. The Diagnostic Considerations and Clinical Management of Lower Lip Swellings in Adolescents: A Narrative Review. Cureus. 2024 Oct 17;16(10):e71707. doi: 10.7759/cureus.71707. PMID: 39553086; PMCID: PMC11568828.
Assa'ad A. Three cases with three different causes of lip and mouth swelling. World Allergy Organ J. 2015 Apr 8;8(Suppl 1):A222. doi: 10.1186/1939-4551-8-S1-A222. PMCID: PMC4407171.
Krishnan B, Basu D, Daniel JM. A discrete swelling of the upper lip: a diagnostic and clinical stepladder. J Maxillofac Oral Surg. 2014 Sep;13(3):300-4. doi: 10.1007/s12663-013-0531-6. Epub 2013 May 5. PMID: 25018604; PMCID: PMC4082540.
Q.
What Could Cause a Big White Bump on My Lip?
A.
A big white bump on your lip might be a mucocele. It’s important to watch for changes or discomfort and get evaluated by a healthcare professional if you’re concerned.
References:
InformedHealth.org](http://informedhealth.org/) [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Canker sores (mouth ulcers) [Updated 2022 Oct 17]. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK546250/
https://www.ncbi.nlm.nih.gov/books/NBK546250/
Updated 2023 Jan 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK560481/
https://www.ncbi.nlm.nih.gov/books/NBK560481/
Updated 2024 Jan 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK570596/
Q.
What Could Cause Tiny Bumps on My Lips If They're Not Cold Sores?
A.
Tiny bumps on your lips that are not cold sores can be due to small benign growths like lipomas or reactive tissue changes, and they are usually not harmful.
References:
Langton SG. Oral and maxillofacial pathology: A rationale for diagnosis and treatment. _Br J Oral Maxillofac Surg_. 2003;41(4):282.
Furlong MA, O'Connell JX, Somach SC, et al. Lipoma of the oral and maxillofacial region: Site and subclassification of 125 cases. _Oral Surg Oral Med Oral Pathol Oral Radiol Endod_. 2004;98(4):441-450. doi:10.1016/j.tripleo.2004.04.022
Angiero F, Berenzi A, Benetti A, Rossi E, Del Sordo R, Sidoni A, Stefani M, Dessy E. Expression of p16, p53 and Ki-67 proteins in the progression of epithelial dysplasia of the oral cavity. Anticancer Res. 2008 Sep-Oct;28(5A):2535-9. PMID: 19035275.
Q.
What Might a Hard White Bump on My Lip Indicate?
A.
A hard white bump on your lip might be a harmless condition called milia, which is a tiny cyst made of trapped keratin, but other causes are possible and a check-up with a doctor is a good idea.
References:
Yadav S, Dogra S, Sarangal R, Kanwar AJ. White growth on lip. J Cutan Aesthet Surg. 2012 Apr;5(2):154-5. doi: 10.4103/0974-2077.99466. PMID: 23060715; PMCID: PMC3461797.
Bansal S, Shaikh S, Desai RS, Ahmad I, Puri P, Prasad P, Shirsat P, Gundre D. Spectrum of Lip Lesions in a Tertiary Care Hospital: An Epidemiological Study of 3009 Indian Patients. Indian Dermatol Online J. 2017 Mar-Apr;8(2):115-119. doi: 10.4103/2229-5178.202280. PMID: 28405551; PMCID: PMC5372431.
Updated 2023 Jan 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK560481/
Q.
What Could a Red Bump on the Inside of My Lip Mean?
A.
A red bump inside your lip can be seen with common conditions like an aphthous ulcer (canker sore) or a pyogenic granuloma. These bumps are generally benign and may occur because of irritation, minor injury, or other factors.
References:
Altenburg A, El-Haj N, Micheli C, Puttkammer M, Abdel-Naser MB, Zouboulis CC. The treatment of chronic recurrent oral aphthous ulcers. Dtsch Arztebl Int. 2014 Oct 3;111(40):665-73. doi: 10.3238/arztebl.2014.0665. PMID: 25346356; PMCID: PMC4215084
Ting PT, Barankin B. Dermacase. Pyogenic granuloma. Can Fam Physician. 2006 Jan;52(1):35-6. PMID: 16477907; PMCID: PMC1479733.
McNamara KK, Kalmar JR. Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities. Head Neck Pathol. 2019 Mar;13(1):4-15. doi: 10.1007/s12105-019-01002-8. Epub 2019 Jan 29. PMID: 30693460; PMCID: PMC6405795.
Q.
What Might a Painless Bump on My Upper Lip Indicate?
A.
A painless bump on your upper lip could be a benign growth like a solitary fibrous tumor or fibroma, but it is important to watch for any changes.
References:
Langton SG. Oral and maxillofacial pathology: A rationale for diagnosis and treatment. _Br J Oral Maxillofac Surg_. 2003;41(4):282.
Scully C, Bagan J. Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications. Oral Dis. 2009 Sep;15(6):388-99. doi: 10.1111/j.1601-0825.2009.01563.x. Epub 2009 Apr 2. PMID: 19371401.
Shmuly T, Ben Zvi Y, Chaushu G, Kaplan I. Oral Solitary Fibrous Tumor: A Retrospective Clinico-Pathological Study and Long-Term Follow-Up. _Medicina_. 2021; 57(2):152. https://doi.org/10.3390/medicina57020152
Q.
What Could a Hard Bump on My Lip Line Indicate?
A.
A hard bump on your lip line can be caused by several different things, such as pimples, epidermoid cysts, or inflammatory conditions.
References:
Phukan JP, Sinha A, Pal S, Jalan S. Cytodiagnosis of epidermoid cyst of the upper lip: a common lesion in an uncommon site. J Lab Physicians. 2014 Jan;6(1):60-2. doi: 10.4103/0974-2727.129097. PMID: 24696565; PMCID: PMC3969648.
Litaiem N, Ben Slimane M, Bacha T, Rammeh S, Zeglaoui F. Cheilitis with hemorrhagic crusts of the vermilion lips. Int J Dermatol. 2020 Jul;59(7):e234-e236. doi: 10.1111/ijd.14814. Epub 2020 Feb 3. PMID: 32010965.
Girgis S, Cheng L. Rare occurrence of lip spindle cell lipoma. Case Rep Oncol Med. 2015;2015:382925. doi: 10.1155/2015/382925. Epub 2015 Feb 25. PMID: 25815220; PMCID: PMC4359822.
Q.
What Could a Bump on the Inside of My Lip Mean?
A.
A bump on the inside of your lip might be from a small injury that causes a mucus buildup, an infection, or rarely, a benign tumor.
References:
Glick M, Siegel MA. Viral and fungal infections of the oral cavity in immunocompetent patients. Infect Dis Clin North Am. 1999 Dec;13(4):817-31, vi. doi: 10.1016/s0891-5520(05)70110-0. PMID: 10579110.
Langton SG. Oral and maxillofacial pathology: A rationale for diagnosis and treatment. _Br J Oral Maxillofac Surg_. 2003;41(4):282.
Pires FR, Silva M, Costa M, et al. Clinical, histological, and immunohistochemical features of ectomesenchymal chondromyxoid tumor. _Oral Surg Oral Med Oral Pathol Oral Radiol Endod_. 2009;108(6):914-919. doi:10.1016/j.tripleo.2009.07.023
Q.
Should I Be Concerned about Tiny, Painless Bumps on My Lips?
A.
Tiny, painless bumps on your lips are usually not a major cause for concern. They are often benign but should be monitored for any changes over time.
References:
Glick M, Siegel MA. Viral and fungal infections of the oral cavity in immunocompetent patients. Infect Dis Clin North Am. 1999 Dec;13(4):817-31, vi. doi: 10.1016/s0891-5520(05)70110-0. PMID: 10579110.
Chocolatewala NM, Chaturvedi P. Role of human papilloma virus in the oral carcinogenesis: an Indian perspective. J Cancer Res Ther. 2009 Apr-Jun;5(2):71-7. doi: 10.4103/0973-1482.52788. PMID: 19542661.
Scully C, Bagan J. Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications. Oral Dis. 2009 Sep;15(6):388-99. doi: 10.1111/j.1601-0825.2009.01563.x. Epub 2009 Apr 2. PMID: 19371401.
Q.
Why Is There a Swollen Bump on My Lip?
A.
A swollen bump on your lip is often a fluid-filled cyst called a mucocele, which usually occurs on the lower lip after small injuries that cause saliva to collect under the skin. However, other causes like infections or allergies might also result in such bumps.
References:
Shirbhate U, Bajaj P, Patil M, Dare S. Mucous Extravasation Cyst Associated With the Lower Lip and Its Management: A Case Report. Cureus. 2023 Oct 5;15(10):e46557. doi: 10.7759/cureus.46557. PMID: 37933354; PMCID: PMC10625657.
Błochowiak KJ, Kamiński B, Witmanowski H, Sokalski J. Selected presentations of lip enlargement: clinical manifestation and differentiation. Postepy Dermatol Alergol. 2018 Feb;35(1):18-25. doi: 10.5114/ada.2018.73160. Epub 2018 Feb 20. PMID: 29599668; PMCID: PMC5872243.
Kannan N, Ramalingam K, Kizhakkoottu S, Ramani P. The Diagnostic Considerations and Clinical Management of Lower Lip Swellings in Adolescents: A Narrative Review. Cureus. 2024 Oct 17;16(10):e71707. doi: 10.7759/cureus.71707. PMID: 39553086; PMCID: PMC11568828.
Q.
What Are the Possible Causes of a Bump on My Lip?
A.
A bump on your lip can have many causes including infections, healing from an injury, benign growths like nerve cell tumors, or rarely, early signs of cancer.
References:
Glick M, Siegel MA. Viral and fungal infections of the oral cavity in immunocompetent patients. Infect Dis Clin North Am. 1999 Dec;13(4):817-31, vi. doi: 10.1016/s0891-5520(05)70110-0. PMID: 10579110.
Choi S, Myers JN. Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy. J Dent Res. 2008 Jan;87(1):14-32. doi: 10.1177/154405910808700104. Erratum in: J Dent Res. 2008 Feb;87(2):191. PMID: 18096889.
Alotaiby FM, Fitzpatrick S, Upadhyaya J, Islam MN, Cohen D, Bhattacharyya I. Demographic, Clinical and Histopathological Features of Oral Neural Neoplasms: A Retrospective Study. Head Neck Pathol. 2019 Jun;13(2):208-214. doi: 10.1007/s12105-018-0943-1. Epub 2018 Jun 21. PMID: 29931661; PMCID: PMC6513954.
Q.
What Might a Big Red Bump on My Lip Indicate?
A.
A big red bump on your lip might be a benign vascular lesion, such as a hemangioma or pyogenic granuloma, though other causes are also possible.
References:
Tobouti PL, Olegário I, de Sousa SC. Benign vascular lesions of the lips: Diagnostic approach. J Cutan Pathol. 2017 May;44(5):451-455. doi: 10.1111/cup.12911. Epub 2017 Feb 16. PMID: 28111788.
Biancardi MR, Silveira HAD, Fernandes D, Almeida LY, Ortega RM, León JE, Bufalino A. Ecstasy Abuse and Its Effects on the Oral Mucosa. J Craniofac Surg. 2019 May/Jun;30(3):e189-e191. doi: 10.1097/SCS.0000000000005033. PMID: 30882567.
Kittridge A, Routhouska SB, Korman NJ. Dermatologic manifestations of Sjögren syndrome. J Cutan Med Surg. 2011 Jan-Feb;15(1):8-14. doi: 10.2310/7750.2010.09033. PMID: 21291650.
Q.
What Could Cause My Lip to Swell Out of Nowhere?
A.
Your lip might swell suddenly because of an infection or an allergic reaction.
References:
Amin D, Satishchandran S, Drew S, Abramowicz S. Diagnosis and Treatment of Lip Infections. J Oral Maxillofac Surg. 2021 Jan;79(1):133-140. doi: 10.1016/j.joms.2020.06.025. Epub 2020 Jun 20. PMID: 32673574.
Alciato L, Bonfils P, Rubin F. Unilateral oral, pharyngeal and laryngeal vesicles. Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Apr;136(2):141-142. doi: 10.1016/j.anorl.2018.11.004. Epub 2018 Dec 13. PMID: 30553733.
Lakhani S, Barnett S, Tappuni AR, Rajakulasingam RK. Recurrent lip swelling: a diagnostic challenge. BMJ Case Rep. 2014 Aug 21;2014:bcr2013203018. doi: 10.1136/bcr-2013-203018. PMID: 25188924; PMCID: PMC4154022.
Q.
Are Tiny White Bumps on My Lips a Sign of HPV?
A.
Tiny white bumps on your lips are usually not a sign of HPV; they are more often benign features or other common oral findings.
References:
Scully C, Bagan J. Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications. Oral Dis. 2009 Sep;15(6):388-99. doi: 10.1111/j.1601-0825.2009.01563.x. Epub 2009 Apr 2. PMID: 19371401.
Markopoulos AK. Role of human papillomavirus in the pathogenesis of oral squamous cell carcinoma. World J Exp Med. 2012 Aug 20;2(4):65-9. doi: 10.5493/wjem.v2.i4.65. PMID: 24520535; PMCID: PMC3905593.
Bharti AH, Chotaliya K, Marfatia YS. An update on oral human papillomavirus infection. Indian J Sex Transm Dis AIDS. 2013 Jul;34(2):77-82. doi: 10.4103/0253-7184.120533. PMID: 24339456; PMCID: PMC3841675.
Q.
Why Did My Lips Get Swollen Out of Nowhere?
A.
Lip swelling may occur due to allergies, infections, or other less common causes. It is important to watch for other symptoms and seek help if the swelling worsens or you have trouble breathing.
References:
Mahmoud A, Bathobakae L, Giannetti R, Naaman G, Affortunato J. Acute Lower Lip Swelling: A Mere Anaphylactic Reaction or a Rare Abscess Location? Cureus. 2023 Nov 17;15(11):e48971. doi: 10.7759/cureus.48971. PMID: 38106723; PMCID: PMC10725739.
Lakhani S, Barnett S, Tappuni AR, Rajakulasingam RK. Recurrent lip swelling: a diagnostic challenge. BMJ Case Rep. 2014 Aug 21;2014:bcr2013203018. doi: 10.1136/bcr-2013-203018. PMID: 25188924; PMCID: PMC4154022.
Krishnan B, Basu D, Daniel JM. A discrete swelling of the upper lip: a diagnostic and clinical stepladder. J Maxillofac Oral Surg. 2014 Sep;13(3):300-4. doi: 10.1007/s12663-013-0531-6. Epub 2013 May 5. PMID: 25018604; PMCID: PMC4082540.
Q.
What Could a Bump on My Lip Line Indicate?
A.
A bump on your lip line could indicate several conditions, such as a mucocele, a cyst, a fungal infection, actinic cheilitis, or a cold sore.
References:
Nallasivam KU, Sudha BR. Oral mucocele: Review of literature and a case report. J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S731-3. doi: 10.4103/0975-7406.163516. PMID: 26538955; PMCID: PMC4606697.
Santos HB, Rolim LS, Barros CC, Cavalcante IL, Freitas RD, Souza LB. Dermoid and epidermoid cysts of the oral cavity: a 48-year retrospective study with focus on clinical and morphological features and review of main topics. Med Oral Patol Oral Cir Bucal. 2020 May 1;25(3):e364-e369. doi: 10.4317/medoral.23388. PMID: 32134895; PMCID: PMC7211364.
Rajendra Santosh AB, Muddana K, Bakki SR. Fungal Infections of Oral Cavity: Diagnosis, Management, and Association with COVID-19. SN Compr Clin Med. 2021;3(6):1373-1384. doi: 10.1007/s42399-021-00873-9. Epub 2021 Mar 27. PMID: 33817556; PMCID: PMC8003891.
Muse ME, Crane JS. Actinic Cheilitis. [Updated 2023 Jul 31]. In: StatPearls [Internet].
Q.
How Can I Get Rid of a Swollen Bump on My Lip?
A.
The best treatment for a bump on the lip depends on finding the right diagnosis.
References:
Gudi SS, Sikkerimath BC, Puranik RS, Kasbe SS. Swelling on lower lip…not always a mucocele !!! Ann Maxillofac Surg. 2013 Jan;3(1):98-9. doi: 10.4103/2231-0746.110080. PMID: 23662271; PMCID: PMC3645623.
Błochowiak KJ, Kamiński B, Witmanowski H, Sokalski J. Selected presentations of lip enlargement: clinical manifestation and differentiation. Postepy Dermatol Alergol. 2018 Feb;35(1):18-25. doi: 10.5114/ada.2018.73160. Epub 2018 Feb 20. PMID: 29599668; PMCID: PMC5872243.
Mohamad I, Muhamed NA, Abdul Hamid SS. Swelling on the inner aspect of the lower lip. Malays Fam Physician. 2014 Aug 31;9(2):64. PMID: 25893070; PMCID: PMC4399407.
Q.
What Could a Red Bump on My Lip Be If It's Not a Cold Sore?
A.
A red bump on your lip that isn’t a cold sore might be a harmless growth like a cherry angioma, a mucocele, an acne lesion, or even a Fordyce spot that has become slightly irritated.
References:
Winston MH, Shalita AR. Acne vulgaris. Pathogenesis and treatment. Pediatr Clin North Am. 1991 Aug;38(4):889-903. doi: 10.1016/s0031-3955(16)38158-5. PMID: 1831256.
Lee JH, Lee JH, Kwon NH, Yu DS, Kim GM, Park CJ, Lee JD, Kim SY. Clinicopathologic Manifestations of Patients with Fordyce's Spots. Ann Dermatol. 2012 Feb;24(1):103-6. doi: 10.5021/ad.2012.24.1.103. Epub 2012 Feb 2. PMID: 22363169; PMCID: PMC3283840.
More CB, Bhavsar K, Varma S, Tailor M. Oral mucocele: A clinical and histopathological study. J Oral Maxillofac Pathol. 2014 Sep;18(Suppl 1):S72-7. doi: 10.4103/0973-029X.141370. PMID: 25364184; PMCID: PMC4211243.
Fernandez-Flores A, Colmenero I. Campbell de Morgan Spots (Cherry Angiomas) Show Endothelial Proliferation. Am J Dermatopathol. 2018 Dec;40(12):894-898. doi: 10.1097/DAD.0000000000001216. PMID: 30024413.
Maymone MBC, Greer RO, Burdine LK, Dao-Cheng A, Venkatesh S, Sahitya PC, Maymone AC, Kesecker J, Vashi NA. Benign oral mucosal lesions: Clinical and pathological findings. J Am Acad Dermatol. 2019 Jul;81(1):43-56. doi: 10.1016/j.jaad.2018.09.061. Epub 2018 Nov 14. PMID: 30447312.
Q.
What Are the Treatment Options for a Small Red Bump on My Lip?
A.
Treatment of small red bumps on the lips depends on the cause.
References:
InformedHealth.org](http://informedhealth.org/) [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Cold sores. [Updated 2025 Jan 14]. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK525782/
https://www.ncbi.nlm.nih.gov/books/NBK525782/
Bhutta BS, Hafsi W. Cheilitis. [Updated 2023 Aug 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470592/
Georgakopoulou E, Loumou P, Grigoraki A, Panagiotopoulos A. Isolated lip dermatitis (atopic cheilitis), successfully treated with topical tacrolimus 0.03. Med Oral Patol Oral Cir Bucal. 2021 May 1;26(3):e357-e360. doi: 10.4317/medoral.24230. PMID: 33340078; PMCID: PMC8141307.
Q.
Why Do I Have a Red Spot on My Lip with No Pain?
A.
A red spot on your lip with no pain can be a benign change in your blood vessels, like a cherry hemangioma, or a small spot from a minor bleed called a petechial hemorrhage. Both are usually harmless.
References:
Jaffe FA. Petechial hemorrhages. A review of pathogenesis. Am J Forensic Med Pathol. 1994 Sep;15(3):203-7. doi: 10.1097/00000433-199409000-00004. PMID: 7825548.
Glick M, Siegel MA. Viral and fungal infections of the oral cavity in immunocompetent patients. Infect Dis Clin North Am. 1999 Dec;13(4):817-31, vi. doi: 10.1016/s0891-5520(05)70110-0. PMID: 10579110.
Lee JH, Lee JH, Kwon NH, Yu DS, Kim GM, Park CJ, Lee JD, Kim SY. Clinicopathologic Manifestations of Patients with Fordyce's Spots. Ann Dermatol. 2012 Feb;24(1):103-6. doi: 10.5021/ad.2012.24.1.103. Epub 2012 Feb 2. PMID: 22363169; PMCID: PMC3283840.
Qadeer HA, Singal A, Patel BC. Cherry Hemangioma. [Updated 2023 Apr 3]. In: StatPearls [Internet].
Q.
What Are the Possible Causes of a Small White Bump on My Lip?
A.
A small white bump on your lip can be caused by several things such as Fordyce spots, aphthous ulcers, or even minor infections. Most of these bumps are harmless, but it’s good to keep an eye on them.
References:
Woo SB, Sonis ST. Recurrent aphthous ulcers: a review of diagnosis and treatment. J Am Dent Assoc. 1996 Aug;127(8):1202-13. doi: 10.14219/jada.archive.1996.0412. PMID: 8803396.
Glick M, Siegel MA. Viral and fungal infections of the oral cavity in immunocompetent patients. Infect Dis Clin North Am. 1999 Dec;13(4):817-31, vi. doi: 10.1016/s0891-5520(05)70110-0. PMID: 10579110.
Lee JH, Lee JH, Kwon NH, Yu DS, Kim GM, Park CJ, Lee JD, Kim SY. Clinicopathologic Manifestations of Patients with Fordyce's Spots. Ann Dermatol. 2012 Feb;24(1):103-6. doi: 10.5021/ad.2012.24.1.103. Epub 2012 Feb 2. PMID: 22363169; PMCID: PMC3283840.
Stoopler ET, Sollecito TP. Oral mucosal diseases: evaluation and management. Med Clin North Am. 2014 Nov;98(6):1323-52. doi: 10.1016/j.mcna.2014.08.006. Epub 2014 Sep 22. PMID: 25443679.
Q.
What Might a Hard Bump on My Lip Indicate?
A.
A hard bump on your lip might be a benign (non-cancerous) growth called a fibroma from repeated irritation, or it could be a different type of lesion that sometimes needs checking by a doctor.
References:
Glick M, Stoopler ET, Lynch DP. Viral and fungal infections of the oral cavity in immunocompetent patients. _Infect Dis Clin North Am_. 1999;13(4):817-831.
Nallasivam KU, Sudha BR. Oral mucocele: Review of literature and a case report. J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S731-3. doi: 10.4103/0975-7406.163516. PMID: 26538955; PMCID: PMC4606697.
Beaty CS, Short AG, Mewar P. Oral Mucosal Lesions, Immunologic Diseases. [Updated 2023 Nov 14]. In: StatPearls [Internet].
Q.
Why Do I Have a Bump on the Inside of My Lip?
A.
A bump on the inside of your lip can be a harmless small cyst called a mucocele or an aphthous ulcer from irritation or trauma. Although many bumps are not serious, it’s important to watch for changes like growth, pain, or changes in color and have a doctor check it if you’re worried.
References:
Sciubba JJ. Oral cancer. The importance of early diagnosis and treatment. Am J Clin Dermatol. 2001;2(4):239-51. doi: 10.2165/00128071-200102040-00005. PMID: 11705251.
Rhee SH, Kim YB, Lee ES. Comparison of Behcet's disease and recurrent aphthous ulcer according to characteristics of gastrointestinal symptoms. J Korean Med Sci. 2005 Dec;20(6):971-6. doi: 10.3346/jkms.2005.20.6.971. PMID: 16361807; PMCID: PMC2779329.
Chaitanya P, Praveen D, Reddy M. Mucocele on Lower Lip: A Case Series. Indian Dermatol Online J. 2017 May-Jun;8(3):205-207. doi: 10.4103/idoj.IDOJ_151_16. PMID: 28584760; PMCID: PMC5447343.
Bansal S, Shaikh S, Desai RS, Ahmad I, Puri P, Prasad P, Shirsat P, Gundre D. Spectrum of Lip Lesions in a Tertiary Care Hospital: An Epidemiological Study of 3009 Indian Patients. Indian Dermatol Online J. 2017 Mar-Apr;8(2):115-119. doi: 10.4103/2229-5178.202280. PMID: 28405551; PMCID: PMC5372431.
Q.
What Could a Painless White Bump on My Lip Be?
A.
A painless white bump on your lip is often a benign finding, such as a milia, which is a tiny cyst filled with keratin. It’s usually not harmful, but a healthcare professional can examine it if you're worried.
References:
Mortazavi H, Safi Y, Baharvand M, Jafari S, Anbari F, Rahmani S. Oral White Lesions: An Updated Clinical Diagnostic Decision Tree. Dent J (Basel). 2019 Feb 7;7(1):15. doi: 10.3390/dj7010015. PMID: 30736423; PMCID: PMC6473409.
Gallardo Avila PP, Mendez MD. Milia. [Updated 2023 Jan 31]. In: StatPearls [Internet].
McKinney R, Olmo H, McGovern B. Benign Chronic White Lesions of the Oral Mucosa. [Updated 2024 Jan 11]. In: StatPearls [Internet].
Q.
What Might a Small Red Bump on My Lip Indicate?
A.
A small red bump on your lip is usually not serious. It could be acne, Fordyce spots, cheilitis, or another vascular or inflammatory condition.
References:
Winston MH, Shalita AR. Acne vulgaris. Pathogenesis and treatment. Pediatr Clin North Am. 1991 Aug;38(4):889-903. doi: 10.1016/s0031-3955(16)38158-5. PMID: 1831256.
Lee JH, Lee JH, Kwon NH, Yu DS, Kim GM, Park CJ, Lee JD, Kim SY. Clinicopathologic Manifestations of Patients with Fordyce's Spots. Ann Dermatol. 2012 Feb;24(1):103-6. doi: 10.5021/ad.2012.24.1.103. Epub 2012 Feb 2. PMID: 22363169; PMCID: PMC3283840.
Lugović-Mihić L, Pilipović K, Crnarić I, Šitum M, Duvančić T. Differential Diagnosis of Cheilitis - How to Classify Cheilitis? Acta Clin Croat. 2018 Jun;57(2):342-351. doi: 10.20471/acc.2018.57.02.16. PMID: 30431729; PMCID: PMC6531998.
McNamara KK, Kalmar JR. Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities. Head Neck Pathol. 2019 Mar;13(1):4-15. doi: 10.1007/s12105-019-01002-8. Epub 2019 Jan 29. PMID: 30693460; PMCID: PMC6405795.
Bhutta BS, Hafsi W. Cheilitis. [Updated 2023 Aug 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
Q.
What Could Cause Tiny Bumps on the Corners of My Lips?
A.
Tiny bumps near the corners of the lips could be caused by cold sores, Fordyce spots, or angular cheilitis. Each of these conditions has its own features and may need different care.
References:
InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Cold sores. [Updated 2025 Jan 14]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK525782/
Lee JH, Lee JH, Kwon NH, Yu DS, Kim GM, Park CJ, Lee JD, Kim SY. Clinicopathologic Manifestations of Patients with Fordyce's Spots. Ann Dermatol. 2012 Feb;24(1):103-6. doi: 10.5021/ad.2012.24.1.103. Epub 2012 Feb 2. PMID: 22363169; PMCID: PMC3283840.
Federico JR, Basehore BM, Zito PM. Angular Chelitis. [Updated 2023 Mar 7]. In: StatPearls [Internet].
Q.
What Could Cause a Bump on My Lip to Appear Out of Nowhere?
A.
A bump on your lip that appears suddenly could be acne, a mucocele, a hemangioma, actinic cheilitis, or another type of lip lesion.
References:
Gudi SS, Sikkerimath BC, Puranik RS, Kasbe SS. Swelling on lower lip…not always a mucocele !!! Ann Maxillofac Surg. 2013 Jan;3(1):98-9. doi: 10.4103/2231-0746.110080. PMID: 23662271; PMCID: PMC3645623.
Mangal S, Padhiar B, Karia U, Shah BJ. Senile hemangioma of the lips. Indian J Dermatol. 2014 Nov;59(6):633. doi: 10.4103/0019-5154.143580. PMID: 25484424; PMCID: PMC4248532.
Muse ME, Crane JS. Actinic Cheilitis. [Updated 2023 Jul 31]. In: StatPearls [Internet].
Marano AA, Therattil PJ, Viviano SL, Datiashvili RO. A growing lesion of the lip. Eplasty. 2015 Apr 18;15:ic24. PMID: 25987947; PMCID: PMC4406233.
Bansal S, Shaikh S, Desai RS, Ahmad I, Puri P, Prasad P, Shirsat P, Gundre D. Spectrum of Lip Lesions in a Tertiary Care Hospital: An Epidemiological Study of 3009 Indian Patients. Indian Dermatol Online J. 2017 Mar-Apr;8(2):115-119. doi: 10.4103/2229-5178.202280. PMID: 28405551; PMCID: PMC5372431.
Q.
Why Is There a Small Bump on My Lip?
A.
A small bump on your lip might be from a blocked salivary gland (called a mucocele), a cold sore, a form of acne, or even an allergic reaction.
References:
Whitley R, Kimberlin DW, Prober CG. Pathogenesis and disease. In: Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007. Chapter 32. Available from: https://www.ncbi.nlm.nih.gov/books/NBK47449/
Ata-Ali J, Carrillo C, Bonet C, Balaguer J, Peñarrocha M, Peñarrocha M. Oral mucocele: review of the literature. _J Clin Exp Dent_. 2010;2(1):e18-21. doi:10.4317/jced.2.e18.
Eichenfield DZ, Sprague J, Eichenfield LF. Management of Acne Vulgaris: A Review. JAMA. 2021 Nov 23;326(20):2055-2067. doi: 10.1001/jama.2021.17633. PMID: 34812859.
Litchman G, Nair PA, Atwater AR, et al. Contact Dermatitis. [Updated 2023 Sep 4]. In: StatPearls [Internet].
Q.
What Could a Small Bump on the Inside of My Lip Mean?
A.
A small bump on the inside of your lip could be a harmless build-up of saliva called a mucocele or a small blockage in a salivary gland, sometimes from a tiny stone. These bumps are usually not serious but should be looked at by a health professional if they persist or cause discomfort.
References:
Chaitanya P, Praveen D, Reddy M. Mucocele on Lower Lip: A Case Series. Indian Dermatol Online J. 2017 May-Jun;8(3):205-207. doi: 10.4103/idoj.IDOJ_151_16. PMID: 28584760; PMCID: PMC5447343.
Marano AA, Therattil PJ, Viviano SL, Datiashvili RO. A growing lesion of the lip. Eplasty. 2015 Apr 18;15:ic24. PMID: 25987947; PMCID: PMC4406233.
Suh DW, Lee EJ, Lew BL, Sim WY. Minor salivary gland sialolithiasis of the upper lip. Ann Dermatol. 2013 Nov;25(4):502-4. doi: 10.5021/ad.2013.25.4.502. Epub 2013 Nov 30. PMID: 24371404; PMCID: PMC3870225.
Q.
What Could Cause a Big Bump on My Lip to Appear Out of Nowhere?
A.
A bump on your lip that develops rapidly could be due to a cyst that has become infected but could also be an allergic response called angioedema.
References:
Alharbi FA, Alharthi AA, Alsaadi FN. Perindopril-induced angioedema of the lips and tongue: a case report. J Med Case Rep. 2018 Dec 5;12(1):359. doi: 10.1186/s13256-018-1910-x. PMID: 30514395; PMCID: PMC6280524.
Lesser H, Cohn JE. Hereditary angioedema. Int J Emerg Med. 2021 Jul 29;14(1):43. doi: 10.1186/s12245-021-00364-7. PMID: 34325646; PMCID: PMC8323326.
Bayat R, Borici-Mazi R. A case of anaphylaxis to peppermint. Allergy Asthma Clin Immunol. 2014 Jan 28;10(1):6. doi: 10.1186/1710-1492-10-6. PMID: 24472564; PMCID: PMC3912937.
Q.
What Could a Red, Painless Bump on My Lip Indicate?
A.
Painless swelling on the lips could be related to a mucocele (a clogged salivary gland) or an STD like syphilis.
References:
Lugović-Mihić L, Pilipović K, Crnarić I, Šitum M, Duvančić T. Differential Diagnosis of Cheilitis - How to Classify Cheilitis? Acta Clin Croat. 2018 Jun;57(2):342-351. doi: 10.20471/acc.2018.57.02.16. PMID: 30431729; PMCID: PMC6531998.
Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK482197/
https://www.ncbi.nlm.nih.gov/books/NBK482197/
Krishnan B, Basu D, Daniel JM. A discrete swelling of the upper lip: a diagnostic and clinical stepladder. J Maxillofac Oral Surg. 2014 Sep;13(3):300-4. doi: 10.1007/s12663-013-0531-6. Epub 2013 May 5. PMID: 25018604; PMCID: PMC4082540.
Q.
What Could a Swollen Bump on My Lip Be If It's Not a Cold Sore?
A.
A swollen bump on your lip that isn’t a cold sore might be an abscess (an infected, pus-filled bump) or a salivary duct cyst (a tiny bubble from blocked saliva). It could also be an allergic reaction.
References:
Mahmoud A, Bathobakae L, Giannetti R, Naaman G, Affortunato J. Acute Lower Lip Swelling: A Mere Anaphylactic Reaction or a Rare Abscess Location? Cureus. 2023 Nov 17;15(11):e48971. doi: 10.7759/cureus.48971. PMID: 38106723; PMCID: PMC10725739.
Tandon A, Sircar K, Chowdhry A, Bablani D. Salivary duct cyst on lower lip: A rare entity and literature review. J Oral Maxillofac Pathol. 2014 Sep;18(Suppl 1):S151-6. doi: 10.4103/0973-029X.141375. PMID: 25364168; PMCID: PMC4211227.
Tekcan Şanlı DE, Boyacı Z. Immunocompetent Young Patient Presenting with Unilateral Lip Abscess Due to Peeling Exfoliated Lip Skin. Turk Arch Otorhinolaryngol. 2021 Sep;59(3):239-241. doi: 10.4274/tao.2021.2021-4-9. Epub 2021 Oct 15. PMID: 34713011; PMCID: PMC8527541.
Q.
What Does a Red Bump on Your Lip Mean?
A.
A red bump on your lip can be from several causes like irritation, injury, or a viral infection. It’s important to watch it for changes and talk to a doctor if it doesn’t go away or gets worse.
References:
McNamara KK, Kalmar JR. Erythematous and Vascular Oral Mucosal Lesions: A Clinicopathologic Review of Red Entities. Head Neck Pathol. 2019 Mar;13(1):4-15. doi: 10.1007/s12105-019-01002-8. Epub 2019 Jan 29. PMID: 30693460; PMCID: PMC6405795.
Lugović-Mihić L, Pilipović K, Crnarić I, Šitum M, Duvančić T. Differential Diagnosis of Cheilitis - How to Classify Cheilitis? Acta Clin Croat. 2018 Jun;57(2):342-351. doi: 10.20471/acc.2018.57.02.16. PMID: 30431729; PMCID: PMC6531998.
InformedHealth.org](http://informedhealth.org/) [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Overview: Canker sores (mouth ulcers) [Updated 2022 Oct 17]. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK546250/
Q.
What Could a Small, Red, Painless Bump on My Lip Be?
A.
A small, red, painless bump on your lip might be a benign build-up of mucus called a mucocele (due to a clogged salivary gland). However, determining the cause depends on various factors, so having it looked at by a healthcare professional is a wise idea.
References:
Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: [https://www.ncbi.nlm.nih.gov/books/NBK560855/
https://www.ncbi.nlm.nih.gov/books/NBK560855/
Gudi SS, Sikkerimath BC, Puranik RS, Kasbe SS. Swelling on lower lip…not always a mucocele !!! Ann Maxillofac Surg. 2013 Jan;3(1):98-9. doi: 10.4103/2231-0746.110080. PMID: 23662271; PMCID: PMC3645623.
Venugopal DC, Warrier S A, S E, H T, Ramesh P. Superficial Mucocele: A Rare Presentation. Cureus. 2021 Sep 17;13(9):e18038. doi: 10.7759/cureus.18038. PMID: 34671526; PMCID: PMC8520584.
Q.
What Could Cause a Lump under the Skin Above My Lip?
A.
A lump above your lip may be caused by different conditions including benign (non-cancerous) growths like cysts, cancers, or infections.
References:
Gelidan AG, Arab K. Rare upper lip pleomorphic adenoma presents as cutaneous skin lesion: Case report. Int J Surg Case Rep. 2021 Aug;85:106142. doi: 10.1016/j.ijscr.2021.106142. Epub 2021 Jun 29. PMID: 34265588; PMCID: PMC8281655.
Stojanovic S, Jovanovic M, Vuckovic N. Unusual growth of upper lip squamous cell carcinoma: a case report. Iran Red Crescent Med J. 2015 Mar 31;17(3):e13478. doi: 10.5812/ircmj.13478. PMID: 26019891; PMCID: PMC4441773.
Lee YS, Sim HS, Lee SK. Actinomycosis of the upper lip. Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S131-4. doi: 10.5021/ad.2011.23.S1.S131. Epub 2011 Sep 30. PMID: 22028560; PMCID: PMC3199410.
Q.
What Might a Pea-Sized Lump in My Lip Indicate?
A.
A pea-sized lump in your lip may be a benign (non-cancerous) growth, such as a mucocele. It is important to have any lump evaluated by a doctor if it changes or causes concerns.
References:
Hassona Y, Sawair F, Scully C. Angioleiomyoma of the upper lip. BMJ Case Rep. 2017 May 12;2017:bcr2016219172. doi: 10.1136/bcr-2016-219172. PMID: 28500121; PMCID: PMC5612575.
Ahmad SA, Popli DB, Sircar K, Hasan S. Basal Cell Adenoma of the Upper Lip: Report of a Rare Case With Literature Review. Cureus. 2024 Jan 19;16(1):e52599. doi: 10.7759/cureus.52599. PMID: 38374835; PMCID: PMC10875275.
Mangal S, Padhiar B, Karia U, Shah BJ. Senile hemangioma of the lips. Indian J Dermatol. 2014 Nov;59(6):633. doi: 10.4103/0019-5154.143580. PMID: 25484424; PMCID: PMC4248532.
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